Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,063

Sort By: Relevance

$90K - $120K *

Help us accelerate progress by supporting project managers in delivering financial analyses and technical reports, while collaborating with a dynamic team to drive impactful solutions in utility finan...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$180K - $200K *

Lead strategic initiatives within the Financial Management Group, focusing on client growth, project delivery, and team development while mentoring staff and enhancing service offerings in utility fin...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Business Services

$130K - $175K *

Empower financial analysis and project management in the utility sector. Lead cost-of-service studies, develop client relationships, and mentor junior staff while ensuring quality and timely delivery...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$107K - $178K *

Join a dynamic Cybersecurity team as an IAM Engineer, driving identity strategy and managing IAM infrastructure. Collaborate across functions to enhance security, streamline processes, and ensure comp...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$95K - $158K *

Engage with high voltage operations, ensuring safe, reliable maintenance and training for renewable energy projects. Lead technical support and oversee compliance for BOP and substation systems across...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $200K *

Lead the charge in modernizing backend capabilities and AWS infrastructure, ensuring secure, reliable software development at scale. Collaborate with teams to enhance platform usability and drive prod...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Staffing

$105K - $124K *

Lead and optimize research intern activities, ensuring alignment with project goals and technical standards. Manage workflows, provide coaching, and conduct hands-on research while supporting the Dire...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by leading innovative strategies for AI-enabled maternal care. Drive program implementation, manage complex projects, and engage stakeholders to enhance health outcomes in low- and mi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$125K *

Join a team that's redefining nonprofit leadership. Leverage your expertise to empower organizations, enhance governance, and drive sustainable growth across diverse communities while navigating compl...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Transform your career by leading a dynamic sourcing team, driving strategic initiatives, and shaping sourcing solutions for critical energy infrastructure projects. Your expertise will influence decis...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Energy & Utilities

$193K - $252K *

Join a team that's passionate about solving complex business challenges. As a Principal Solutions Engineer, you'll engage with enterprise clients, drive strategic relationships, and showcase the value...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$101K - $125K *

Drive the execution of immersive projects by providing technical oversight and support, ensuring seamless integration and coordination with partners globally while maintaining high standards of qualit...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitality & Recreation

$80K - $95K *

Accelerate progress at the forefront of cybersecurity by analyzing threats, developing countermeasures, and collaborating with teams to protect critical information systems from malicious activities a...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$85K - $95K *

Engage in the development and execution of automated testing strategies, ensuring software quality through comprehensive test plans and scripts. Collaborate with teams to maintain CI/CD pipelines and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$115K - $125K *

Elevate your career by leading engineering teams in a dynamic environment, driving modernization and integration efforts while ensuring compliance with federal DevSecOps frameworks and delivering inno...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$95K - $125K *

Join a dynamic team to enhance security in CI/CD pipelines, integrating advanced scanning tools and hardening infrastructure across cloud platforms. Drive vulnerability management and ensure complianc...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$95K - $105K *

Join a dynamic team to provision and manage cloud environments, automate deployments, and ensure robust cloud security. Leverage your expertise in AWS or Azure and OpenShift to drive cloud migrations...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Redefine pharmaceutical care by providing tailored drug management and clinical services. Collaborate with healthcare teams to enhance patient safety, participate in goal-oriented initiatives, and ens...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $190K *

Join a team that's dedicated to delivering exceptional anesthesia care. Provide critical support during surgical and diagnostic procedures while enhancing patient safety and comfort through your exper...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $147K *

Lead a dynamic team in enhancing member-centered care through effective utilization management. Drive quality improvement, ensure compliance, and foster strategic partnerships to optimize healthcare d...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$98K - $132K *

Deliver strategic sourcing solutions for Marketing Services, focusing on Content Production and Media. Collaborate cross-functionally to optimize supplier performance, drive innovation, and ensure com...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$147K - $200K *

Drive strategic category management initiatives for Full-Service CRO, collaborating across teams to optimize procurement processes, reduce costs, and enhance supplier performance while ensuring compli...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$107K - $180K *

Drive the strategy and operations of a dynamic contingent workforce program, enhancing governance and service delivery. Collaborate cross-functionally to implement scalable processes and support inter...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$74K - $118K *

Empower cross-functional teams by managing account workflows, resolving issues, and enhancing service quality. Utilize data-driven insights to streamline processes and mentor team members, ensuring a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$225K - $280K *

Engage as a key technical resource for channel sales, driving success with global partners. Leverage your expertise in networking solutions to enhance relationships, deliver impactful demos, and suppo...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.