Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,063

Sort By: Relevance

$90K - $100K *

Lead the charge in shaping innovative creator ad campaigns, managing end-to-end processes while leveraging AI to enhance performance. Collaborate cross-functionally to deliver impactful content and ma...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$106K - $177K *

Unlock potential by leading cross-functional teams to shape product strategy, drive growth, and enhance customer value through data-driven insights and innovative solutions across the full product lif...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $170K *

Drive financial evaluations and execution of acquisitions in medical aesthetics, analyzing opportunities and supporting leadership in negotiations. This hands-on role requires expertise in financial a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $250K *

Pioneer your career by leading a dynamic sales team focused on Labor and Public Sector markets. Drive growth, mentor talent, and execute strategic initiatives to exceed revenue goals while building im...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Build lasting relationships and drive customer success by leveraging insights and data to enhance client engagement and retention. Collaborate cross-functionally to inform product improvements and sup...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $120K *

Elevate mental health support by providing remote counseling services to clients. Utilize your expertise to assess, plan, and deliver effective therapy, ensuring a positive impact on individuals' emot...

Pascagoula, MSRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Join us to provide impactful remote counseling services, helping clients navigate emotional and mental health challenges. Enjoy a structured weekday schedule while making a meaningful difference throu...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$155K - $175K *

Empower engineering teams by leading the evolution of cloud, security, and AI operations. Drive platform reliability and DevSecOps practices while mentoring others to foster a collaborative, innovativ...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$142K - $178K *

Shape the future of technology storytelling by crafting compelling narratives that highlight innovation and AI. Collaborate with leaders to elevate Mercury's brand through integrated communications, e...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$200K - $240K *

Innovate with us to lead a dynamic marketing organization, driving brand preference and demand generation. Collaborate across teams to align strategies with commercial goals, ensuring impactful campai...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$66K - $117K *

Oversee and enhance facilities operations, construction, and maintenance projects. Lead a team to ensure timely, safe, and budget-compliant execution of facility improvements and maintenance activitie...

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$165K - $205K *

Lead the charge in cybersecurity governance and risk management consulting. Drive client engagements, develop security frameworks, and mentor teams while ensuring alignment with industry standards and...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$100K - $120K *

Join a dynamic team to lead customer success for SMBs, driving retention and growth. You'll coach a team, streamline onboarding, and leverage data and AI to enhance customer engagement and satisfactio...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$208K - $234K *

Drive the growth of Honeycomb Private Cloud by leading a senior engineering team, enhancing customer relationships, and ensuring operational excellence across multiple engineering domains. Collaborate...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$109K - $136K *

Drive accurate, evidence-based clinical claims while collaborating with Marketing, Legal, and Clinical teams. Build and manage the claims framework and evidence library to support bold, compliant mark...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $214K *

Lead the charge in designing and implementing enterprise Finance solutions, optimizing processes, and driving global transformation initiatives through innovative technology and collaboration with sta...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$140K - $165K *

Empower teams by leading complex, cross-functional programs that enhance cloud infrastructure. Drive execution through ambiguity, ensuring high-impact delivery while collaborating with engineering and...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$161K - $195K *

Drive Oracle Fusion Financials transformation by owning product vision, delivery, and finance domain initiatives. Collaborate with leadership to ensure effective system design, governance, and automat...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform your career by leading Microsoft Cloud security projects, deploying SIEM and XDR solutions, and enhancing customer environments. Collaborate with a dynamic team to drive innovation in Manage...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $170K *

Lead innovative risk analysis and premium production, driving collaboration across teams to enhance management and professional liability insurance products that resonate with brokers and clients alik...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$173K - $290K *

Join a team that's redefining strategic research by tackling complex, ambiguous challenges. Collaborate with product, design, and engineering leaders to shape impactful insights that drive business de...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$190K - $217K *

Take ownership of a dynamic business unit, driving revenue growth and strategic direction. Lead a cross-functional team to navigate the political landscape, build partnerships, and shape the future of...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $90K *

Elevate community engagement by building trusted relationships with senior living staff and residents. Act as a vital connector, ensuring seamless access to on-site care services while fostering colla...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Take ownership of automating workflows across teams by building AI agents using Claude and Microsoft Copilot. Collaborate with various departments to identify automation opportunities, ensuring securi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Join a dynamic team to support high-net-worth clients by preparing complex tax returns, coordinating engagements, and mentoring Associates while enhancing your technical and leadership skills in a col...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.