Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,063
Solutions Engineer - Cloud & DevOps
$90K - $145K *
Unlock your potential by designing CI/CD pipelines and automating processes. Collaborate with teams to enhance development efficiency while ensuring system compliance and security across AWS and Azure...
2 weeks ago
Sr. Strategic Alliance Manager
$150K - $225K *
Engage with us to drive strategic alliances, enhance partnerships, and execute joint initiatives that foster revenue growth and market presence. Collaborate across teams to position solutions effectiv...
2 weeks ago
$110K - $130K *
Lead client relationships and drive strategic growth while ensuring high-quality delivery. Collaborate across teams to align marketing efforts with client objectives and mentor account strategists for...
Reposted 2 weeks ago
Mechanical Design Engineer Level 3/ 4
$89K - $167K *
Advance your career by designing innovative launcher hardware for Navy platforms. Collaborate with engineers to develop concepts, generate models, and support fabrication in a dynamic environment focu...
2 weeks ago
1739 - Senior Director, Strategic Sourcing Facilities- Retail
$160K - $210K *
Join us to drive strategic sourcing initiatives in Facilities, managing project delivery and resource allocation while aligning account objectives with measurable outcomes across diverse client accoun...
2 weeks ago
Business Development and Capture Manager
$110K - $130K *
Join a team that's driving strategic growth across federal agencies by leading capture efforts, developing competitive proposals, and enhancing market intelligence to ensure success in securing contra...
2 weeks ago
$150K - $180K *
Drive mobile engineering excellence across diverse product teams, ensuring strategic direction, fostering collaboration, and enhancing delivery. Lead managers, shape architecture, and cultivate a prod...
2 weeks ago
$150K - $200K *
Innovate robust ML infrastructure to enhance AI capabilities, ensuring seamless model deployment and performance. Collaborate with teams to streamline processes and drive impactful ML systems from res...
2 weeks ago
$163K - $218K *
Shape the future of information security by maintaining and advancing our ISMS while ensuring ISO 27001 and SOC 2 Type 2 compliance. Drive collaborations across teams to build effective processes and...
Reposted 2 weeks ago
Executive Underwriter, Central
$150K - $190K *
Lead the charge in underwriting and managing complex enterprise accounts, driving profitable business through strategic broker partnerships while mentoring junior underwriters and shaping portfolio st...
2 weeks ago
$110K - $140K *
Transform your career by managing employee benefits for diverse clients. Collaborate with Producers and Executives to deliver exceptional service, analyze plans, and drive compliance while fostering s...
2 weeks ago
Separations Field Application Specialist (RTP)
$90K - $110K *
Advance customer success by providing expert application support for separation technologies, driving product trials, and collaborating with sales teams to optimize solutions in the biotechnology sect...
2 weeks ago
$239K - $299K *
Drive the development and scaling of a comprehensive supply chain strategy, ensuring efficient management and delivery of products. Collaborate across teams to optimize performance and support rapid g...
2 weeks ago
Sr. Manager, Sales Strategy and Operations - Omni + OBT
$142K - $197K *
Drive strategic improvements and operational efficiency in Partnerships by establishing frameworks, integrating AI solutions, and optimizing team performance, all while collaborating with cross-functi...
Reposted 2 weeks ago
Project Control Specialist - Remote, US
$103K - $181K *
Optimize project performance by managing cost, schedule, and risk metrics. Collaborate with teams to ensure accurate forecasting and reporting, driving efficiency across large capital construction pro...
2 weeks ago
$148K - $266K *
Lead pricing strategies for a global business unit, managing proposals and compliance while collaborating with cross-functional teams to deliver accurate cost proposals and mitigate risks effectively...
2 weeks ago
$90K - $110K *
Deliver impactful data insights by transforming complex datasets into actionable analytics. Collaborate with stakeholders to enhance decision-making and support advanced analytics initiatives within a...
2 weeks ago
$170K - $190K *
Join us to support strategic customer accounts by providing technical and operational expertise. Collaborate with teams to enhance security operations, optimize workflows, and ensure customer trust in...
2 weeks ago
Director, Market Growth Strategy, Molecule to Market (CMC)
$185K - $256K *
Join a team that's redefining CMC strategies in life sciences. You'll engage with industry leaders, drive software adoption, and shape market narratives to enhance product lifecycle management and ope...
2 weeks ago
Sr Manager - Consumer Lending Client Success
$112K - $176K *
Unlock client success by managing post-sale relationships, driving product adoption, and identifying growth opportunities in the consumer lending sector. Collaborate with internal teams to enhance cli...
2 weeks ago
Microsoft Technical Solutions Architect III -- Copilot Strategy, Customization & Automation
$150K - $170K *
Join a dynamic team driving AI innovation by guiding organizations in adopting Microsoft Copilot and Power Platform. Leverage your technical expertise and strategic insights to enhance productivity an...
2 weeks ago
$142K - $168K *
Elevate our sales engineering efforts by driving business opportunities across LATAM and the Eastern US. Collaborate with sales partners to maximize customer value and deliver compelling product demon...
2 weeks ago
Operations Director, Biomarker Programs
$175K - $200K *
Lead the charge in optimizing biomarker program operations, ensuring seamless sample processing from collection to storage. Collaborate across teams to uphold quality and compliance while driving grow...
2 weeks ago
Transmission & Structural Project Manager
$125K - $150K *
Drive impactful projects in electric utility by managing engineering design, client coordination, and business development. Leverage your expertise to enhance project scope, budget, and schedule while...
2 weeks ago
Field Reimbursement Specialist
$94K - $148K *
Optimize patient access by educating healthcare providers on reimbursement processes. As a Field Reimbursement Specialist, you'll navigate complex insurance challenges, ensuring patients receive speci...
2 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.