Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,961

Sort By: Relevance

$80K - $95K *

Join a team that's dedicated to enhancing customer education and satisfaction through expert training on ultrasound products. This hybrid role involves travel and collaboration with healthcare profess...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$168K - $224K *

Lead the strategic direction for People Systems and Workforce Insights, ensuring technology and analytics support equitable decision-making and enhance employee experience across the organization. Dri...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$177K - $236K *

Empower a team of Actuarial Analysts and Consultants, leading pricing projects and analyses. Foster relationships with clients and stakeholders while ensuring high-quality deliverables and timely proj...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $120K *

Contribute to power system studies for high-voltage substations, ensuring reliability and compliance. Collaborate with engineers, support project documentation, and drive continuous improvement initia...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$144K - $212K *

Drive strategic retention initiatives and lead a high-performing team to enhance partner success. Collaborate cross-functionally to optimize engagement and execute competitive strategies, ensuring val...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$77K - $118K *

Join our structural design team to lead innovative projects, utilizing 3D modeling software to create structural layouts and solve complex design challenges. Collaborate with multi-disciplinary teams...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Transform your career by leading global sanctions initiatives, ensuring compliance and risk management as the business scales. Collaborate with experts to navigate complex regulations and make a signi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$107K - $152K *

Transform the future of AI at scale by designing and deploying LLM-powered systems to enhance content quality and safety. Collaborate with a dynamic ML team to tackle complex challenges and make a mea...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Champion innovative sales strategies to secure $10M+ in federal revenue. Build relationships with DHS and federal agencies, develop operational use cases, and convert pilots into sustainable programs...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$132K - $182K *

Lead the charge in crafting compelling MSSP messaging and content, aligning with corporate narratives while enhancing partner enablement. Collaborate cross-functionally to drive sales and operational...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Oversee global EPC proposal processes for Battery Energy Storage Systems, collaborating with cross-functional teams to deliver innovative, customer-centric solutions while driving continuous improveme...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$170K - $200K *

Transform client relationships by leading data-driven solutions for major tech firms. Engage with executives to uncover insights, drive impactful decisions, and ensure seamless delivery across teams i...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$138K - $182K *

Join a dynamic team as you leverage your pre-sales expertise to empower SMB/Commercial customers in cloud security. Deliver impactful demonstrations and training while collaborating with account execu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $185K *

Transform the future of healthcare sourcing by leading strategic initiatives, managing a dedicated team, and driving cost-saving projects across Facilities categories to ensure high-quality service de...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$130K - $160K *

Elevate digital experiences by guiding site operations and enhancing user engagement. Collaborate with cross-functional teams to implement innovative features and optimize performance metrics, driving...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$190K - $225K *

Elevate your career by engaging with key opinion leaders and healthcare professionals. This role focuses on scientific collaboration and strategic partnerships, driving impactful medical insights with...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$155K - $175K *

Lead the charge in client partnerships while driving strategic growth and team development. Utilize your expertise to deliver impactful insights and solutions in a fast-paced, evolving environment, en...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$76K - $90K *

Join a team that's dedicated to delivering exceptional investment management services. This role involves collaborating with Wealth Advisors to strategize and implement portfolio solutions, ensuring a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $116K *

Engage with customers to implement and optimize downstream processing technologies, providing technical expertise and support. Collaborate with stakeholders to enhance workflows and ensure successful...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join us to provide expert application support for cutting-edge separation technologies. Engage with customers throughout their journey, ensuring successful implementation and adoption while collaborat...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $175K *

Join a team that's redefining cloud solutions by architecting innovative CaaS and cloud-native technologies. Collaborate with customers to tackle complex challenges and drive successful cloud transfor...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $260K *

Unlock potential by driving sales growth in the Minnesota East territory, fostering relationships with physicians, and ensuring high adoption of innovative medical technologies while meeting sales quo...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Champion pipeline growth by designing high-impact demand gen strategies across events, webinars, and campaigns, shaping the future of demand generation in a fast-paced environment focused on accountab...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$83K *

Transform the candidate experience by coordinating interviews and managing communications. Collaborate with recruiters and hiring managers to streamline processes, ensuring efficiency and excellence i...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$101K - $145K *

Lead the charge in leveraging advanced data science techniques to solve complex business challenges, mentor junior team members, and drive effective risk management through innovative algorithms and d...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.