Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
$120K - $145K *
Shape the future of Salesforce solutions by designing and implementing innovative architectures that meet client needs. Collaborate with stakeholders to deliver high-value solutions in a dynamic, fast...
1 week ago
Salesforce Solution Consultant
$130K - $140K *
Optimize Salesforce capabilities in a federal environment by leading projects, managing requirements, and enhancing user experiences through effective configuration and migration strategies. Join us t...
1 week ago
U.S. Director of Medical Affairs (US DMA) - Ophthalmology
$190K - $300K *
Transform medical affairs by driving scientific excellence and strategic initiatives in ophthalmology. Collaborate with cross-functional teams to enhance field readiness and optimize engagement across...
1 week ago
Director, Global Regulatory Liaison - Immunology
$173K - $272K *
Unlock potential by leading global regulatory strategies for immunology projects, ensuring compliance and optimizing product approvals. Collaborate with cross-functional teams and regulatory agencies...
Reposted 1 week ago
Senior Analyst, Decision Science (Market Analyst)
$105K - $129K *
Drive impactful market analysis and reporting as a Senior Analyst, leveraging data to guide strategic investments and growth opportunities. Collaborate with teams to enhance decision-making and optimi...
1 week ago
$81K *
Manage and enhance public health technology platforms, ensuring secure, reliable operations for local, state, and federal agencies. Collaborate with cross-functional teams to optimize system performan...
1 week ago
Senior Cyber Security Engineer
$110K - $130K *
Lead the enhancement of security measures for cloud-based healthcare solutions, focusing on vulnerability management, incident response, and compliance. Collaborate with cross-functional teams to ensu...
1 week ago
$100K - $125K *
Join our dynamic finance team as you drive margin and profitability through detailed analysis and strategic insights. Collaborate with senior leadership to transform data into actionable initiatives t...
1 week ago
Enterprise Analytics Consultant - Remote
$122K - $179K *
Advance your career by leading enterprise analytics and data governance initiatives. Collaborate with executive leadership to create analytics solutions that drive strategic decision-making and enhanc...
Reposted 1 week ago
$160K - $180K *
Empower commercial operations by leading a dynamic Deal Desk team, driving strategy, optimizing processes, and executing complex transactions in a fast-paced SaaS environment. Collaborate cross-functi...
1 week ago
Senior Process Engineer - Minerals Processing Operation
$100K - $120K *
Deliver innovative mineral processing solutions to enhance plant operations, optimize costs, and improve product quality. Collaborate with cross-functional teams to drive project success and ensure co...
1 week ago
Licensed Professional Counselor (LPC)
$115K - $120K *
Reimagine behavioral health by delivering impactful counseling services remotely. Engage with clients facing various challenges, conduct evaluations, and maintain thorough documentation while adhering...
1 week ago
Licensed Professional Counselor (LPC)
$115K - $120K *
Provide remote counseling services to adults, addressing mental health concerns through telehealth. Engage in direct client work, evaluate needs, and maintain documentation while adhering to ethical s...
1 week ago
Senior Director Infrastructure Engineering
$175K - $210K *
Transform infrastructure engineering by leading a global team to develop and implement design standards for AI factories, ensuring consistency and efficiency across projects while driving innovation a...
1 week ago
$84K - $112K *
Lead the charge in optimizing network capacity and implementing innovative solutions. Collaborate across teams to ensure best-in-class service delivery while managing projects and driving strategic in...
1 week ago
Senior Business Development Leader - Wright Patterson AFB
$135K - $160K *
Champion growth strategies across defense IT and ISR systems, building senior relationships and managing opportunities at Wright-Patterson AFB. Drive innovation in C2 modernization and lead proposal d...
1 week ago
Director of Program Management
$135K - $160K *
Transform your career by leading cross-functional teams to drive drug development strategies. Collaborate with key stakeholders to ensure successful execution of integrated plans, manage risks, and de...
1 week ago
$94K - $136K *
Transform financial insights into strategic decisions by providing advanced analytical support across Finance, Operations, and Strategic Planning. Collaborate with leadership to drive impactful projec...
1 week ago
$69K - $100K *
Optimize coding operations by leading a team to ensure compliance, accuracy, and efficiency in billing processes. Collaborate with stakeholders to enhance documentation quality and coding integrity wh...
1 week ago
Senior Business Systems Analyst
$107K - $180K *
Lead the resolution of complex integration issues, collaborating with cross-functional teams to enhance reliability and support. Develop documentation and tools that empower partners and improve opera...
1 week ago
Business Analyst, New Construction Sales Analytics
$89K - $150K *
Optimize sales operations by managing forecasting and data analytics to enhance revenue delivery. Collaborate with cross-functional teams to ensure data accuracy and support sales processes, enabling...
1 week ago
Clinical Development Medical Director, Obesity/Cardiovascular
$274K - $371K *
Elevate patient care through innovative clinical strategies in obesity and cardiometabolic development. Collaborate across teams to design and implement late-phase studies, ensuring alignment with glo...
Reposted 1 week ago
HR Compliance and Risk Manager
$80K - $95K *
Shape the future of HR compliance and risk management by leading initiatives that ensure adherence to laws and regulations, partnering with key stakeholders to mitigate risks and enhance operational e...
1 week ago
$100K - $110K *
Transform business opportunities within the public transit sector by leading complex sales cycles and fostering relationships with government agencies to drive growth and implement tailored software s...
Reposted 1 week ago
Technical Account Manager, Public Cloud
$71K - $108K *
Drive customer success by managing technical relationships and advocating for best practices in public cloud environments. Leverage your expertise to enhance customer experiences and ensure alignment...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.