Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,967

Sort By: Relevance

$95K - $115K *

Lead strategic sourcing initiatives and optimize supplier performance within nuclear procurement. Drive category management processes to enhance safety, cost efficiency, and risk mitigation while coll...

1 week ago

  •   11 - 15 years exp.  •   Energy & Utilities

$97K - $133K *

Join a dynamic team to drive sales growth and enhance customer relationships. Manage key accounts, collaborate with cross-functional teams, and ensure exceptional service while achieving ambitious sal...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a dynamic team to drive new business acquisition in a high-growth market. Leverage your expertise in full-cycle sales to build strategic partnerships and achieve uncapped earning potential while...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$68K - $95K *

Shape engaging learning experiences by leveraging your instructional design expertise. Collaborate with teams to develop high-quality, accessible content across various modalities, ensuring compliance...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Partner with us to lead the deployment and integration of Palo Alto PA-450 firewalls within a Cisco SD-WAN environment, ensuring secure, efficient, and scalable multi-site rollouts while collaborating...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $145K *

Elevate revenue and risk strategies by leveraging data insights to drive impactful business decisions. Collaborate across teams to optimize processes, influence product development, and enhance client...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $165K *

Join a dynamic team as a Managing Consultant, driving innovative solutions in Revenue Integrity. Oversee engagements, enhance client relationships, and lead project teams to optimize financial perform...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$74K - $89K *

Elevate healthcare quality by reviewing medical records, ensuring accurate coding, and maintaining compliance with guidelines. Collaborate with teams to enhance coding practices and uphold high standa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$92K - $120K *

Lead a dynamic team of Client Contract Managers to optimize renewal strategies, drive retention, and enhance operational excellence through effective leadership and cross-functional collaboration. Ele...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$86K - $138K *

Unlock innovative healthcare solutions by leading product strategy and lifecycle management for clinical programs. Collaborate across teams to enhance member experiences and drive business value while...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to driving client success through effective implementation of our high-performance product suite. Manage projects, coordinate with clients, and ensure seamless onboarding...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Elevate your career by partnering with clients to enhance FP&A processes, build financial models, and drive operational improvements in a dynamic Private Equity environment. Collaborate with teams to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$89K - $155K *

Lead the design and implementation of a UiPath automation program, establishing governance and operational standards while collaborating with a diverse team to build a Center of Excellence from the gr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Drive the technical relationship with healthcare accounts, ensuring platform adoption, risk mitigation, and customer growth through proactive advisory and strategic planning. Collaborate with IT teams...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$215K - $315K *

Lead the charge in building secure, compliant infrastructure for our DaaS platform. Drive engineering excellence while collaborating with cross-functional teams to meet the needs of regulated customer...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $170K *

Lead the development of scalable systems, balancing individual contributions with technical guidance. Collaborate across teams to tackle complex engineering challenges in security and AI, while evolvi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Join a team that's driving financial strategy and analysis for the Fraud & Security Solutions unit. Collaborate with senior leaders to deliver insightful reporting, manage budgets, and support key bus...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$120K - $145K *

Elevate user experiences by leading UX design initiatives, ensuring coherent and accessible product interactions across diverse workflows. Collaborate cross-functionally to deliver impactful design so...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Lead the transformation of innovative technologies into market-ready products, collaborating with cross-functional teams to identify customer needs, prototype solutions, and drive commercialization fr...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$115K - $161K *

Champion complex partnership tax strategies, providing technical guidance and solutions. Collaborate with national teams to analyze federal tax issues, develop training, and enhance consulting practic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$80K - $95K *

Champion the management of ship testing applications, ensuring compliance and operational efficiency. Lead data evaluation and oversee trial preparations while training personnel to maintain high stan...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$118K - $174K *

Accelerate progress at the forefront of ERP solutions, driving architecture, performance, and custom solutions while collaborating with diverse teams to meet business objectives and enhance system eff...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Grow Product Marketing into a strategic capability, driving go-to-market strategies and product launches. Collaborate across teams to assess needs, create impactful processes, and mentor talent, ensur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Transform data into actionable insights by building models that optimize carrier selection for auto insurance shoppers. Own media buying models to enhance ROAS, ensuring effective deployment and monit...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$80K - $110K *

Unlock potential by leading K-12 district implementations, ensuring successful platform adoption through strategic planning, relationship building, and project management. Collaborate with stakeholder...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.