Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
Principal Group Product Manager- AL Labs
$170K - $243K *
Transform product innovation by leading AI-driven strategies and experiments, collaborating across teams to enhance software solutions and improve employee experiences in a dynamic, fast-paced environ...
1 week ago
Senior Account Executive - Key Accounts
$100K - $200K *
Elevate your career by driving strategic account growth in complex technical sales. Collaborate with top-tier clients to solve manufacturing challenges and build lasting partnerships, all while naviga...
1 week ago
Senior Director, Growth & Demand Marketing
$277K - $350K *
Elevate your career by leading global demand generation strategies, driving enterprise pipeline growth, and optimizing high-impact ABM programs. Collaborate with cross-functional teams to innovate and...
1 week ago
Senior Backend Engineer | Token Spend Management
$135K - $160K *
Transform the future of finance by building backend systems that enhance AI spend visibility and management. Collaborate with cross-functional teams to deliver reliable data solutions and drive impact...
1 week ago
$110K - $130K *
Elevate global post-market surveillance by leading a team focused on safety, compliance, and performance of medical devices. Drive field actions, analyze data, and collaborate cross-functionally to en...
1 week ago
Sr. Director - Advanced Technical Solutions (ATS)
$184K - $276K *
Elevate the execution of large-scale technology initiatives, leading cross-functional teams to translate business goals into effective technical solutions. Drive delivery accountability while connecti...
Reposted 1 week ago
$110K - $130K *
Empower client relationships by managing outsourcing engagements, optimizing processes, and leading a team. Drive operational excellence and identify new opportunities for service expansion while ensu...
1 week ago
PHARMACIST - STAFF (Starkville, MS)
$95K - $115K *
Empower exceptional customer experiences by leading a pharmacy team to deliver outstanding service, ensuring compliance with regulations, and achieving sales goals while fostering a safe and welcoming...
1 week ago
Financial Services Product Manager
$80K - $95K *
Join a dynamic team to lead product strategy and enhance consumer lending operations. Collaborate across departments to define requirements, manage development, and ensure compliance while driving mod...
1 week ago
Medicare Risk Adjustment Compliance Auditor (CPC, CCS, or CCS-P Required) (Remote)
$64K - $96K *
Engage in comprehensive risk adjustment audits and compliance reviews, ensuring accurate data submission to CMS. Collaborate with coding teams and management to uphold regulatory standards and improve...
Reposted 1 week ago
$220K - $320K *
Champion new customer acquisition by leading the full enterprise sales cycle, building relationships with senior decision-makers, and delivering compelling business cases in highly regulated industrie...
1 week ago
Product Marketing Manager, Channel & Ecosystem
$95K - $115K *
Shape the future of partner marketing by developing go-to-market strategies and messaging for diverse channels. Collaborate with cross-functional teams to create impactful narratives and enable partne...
1 week ago
Coporate Commerical Marketing Manager
$110K - $130K *
Transform regional growth by leading strategic pricing initiatives, optimizing commercial strategies, and driving profitability through advanced data analysis and cross-functional collaboration within...
1 week ago
Senior Regulatory Affairs Specialist (Remote - United States)
$124K - $170K *
Champion regulatory strategies to accelerate product approvals and compliance. Lead a dynamic team in supporting innovative medical devices, ensuring alignment with global regulations while fostering...
1 week ago
Senior Liability Claims Adjuster - Municipal Claims (FL License)
$82K - $86K *
Lead the charge in managing complex liability claims, ensuring thorough investigations, evaluations, and negotiations. Collaborate with clients and legal teams to achieve optimal resolutions while adh...
1 week ago
Principal Product Manager, Platform and Shared Capabilities
$120K - $145K *
Transform product capabilities by leading strategy and execution for shared workflows, ensuring seamless integration and user experience across platforms. Drive measurable outcomes through customer in...
1 week ago
$110K - $130K *
Oversee the design and development of clinical databases while ensuring project timelines and quality standards are met. Collaborate across teams to provide technical support and mentor team members...
Reposted 1 week ago
Senior SAP ABAP/ Fiori Developer
$73K - $102K *
Unlock potential by leading SAP ABAP development initiatives, driving innovative solutions, and collaborating with teams to enhance client operations. Your expertise will shape the future of technolog...
1 week ago
Sr. Network Operations Analyst
$110K - $130K *
Elevate network operations by leading complex incident responses and mentoring teams. Collaborate with cross-functional partners to enhance network reliability and operational maturity across global e...
1 week ago
Head of NA Workshop Operations, PAC SER Roll Services
$110K - $130K *
Elevate workshop operations across North America by leading teams, driving safety, and ensuring financial performance. Foster a culture of continuous improvement while collaborating with stakeholders...
1 week ago
$125K - $150K *
Strategize with senior leadership to shape and execute People strategy, driving organizational design and employee relations. Lead initiatives that align talent with business goals during a critical g...
1 week ago
$70K - $100K *
Drive your career forward by managing key partnerships and delivering measurable results. This role blends strategic relationship management with consultative selling, ensuring partner success and gro...
1 week ago
Enterprise Solution Engineer - South East / Mid Atlantic
$110K - $130K *
Innovate at the forefront of data analytics by driving technical presales, engaging with customers, and delivering tailored solutions that enhance business agility and insights. Collaborate with cross...
1 week ago
$85K - $115K *
Engage clients by managing innovative programs that enhance energy solutions. Drive success through strong relationships, effective communication, and strategic problem-solving while collaborating wit...
1 week ago
Experienced Clinical Research Associate | Regionally Aligned Across US
$80K - $95K *
Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.