Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
Senior Director, Patient Recruitment - Remote
$150K - $180K *
Inspire patient recruitment strategies by leading a dynamic team, collaborating with senior management, and leveraging innovative tools to enhance enrollment across clinical trials while ensuring dive...
1 week ago
Principal Product Builder, Data
$205K - $256K *
Transform your career by leading Apollo's data strategy, ensuring the highest quality B2B data for GTM success. Drive product vision, collaborate cross-functionally, and enhance customer experiences t...
1 week ago
$133K - $150K *
Champion innovative finance solutions by owning core accounting operations, driving automation, and enhancing financial reporting. Collaborate across teams to build a scalable finance function that su...
1 week ago
RVP, Sales - Splunk Federal Civilian
$404K - $500K+*
Transform the Federal Civilian landscape by leading sales teams to drive adoption of cybersecurity and data solutions. Cultivate executive relationships, establish GTM strategies, and achieve multi-mi...
1 week ago
$235K - $291K *
Champion strategic leadership across diverse digital and marketing initiatives, guiding cross-disciplinary teams and fostering client relationships to drive impactful solutions and business growth in...
1 week ago
$150K - $180K *
Drive enterprise sales strategy for innovative agentic products, building relationships with key decision-makers. Collaborate with product and engineering teams to translate customer needs into compel...
1 week ago
$110K - $145K *
Optimize compensation strategies by providing expert advisory support, leading complex analyses, and enhancing program effectiveness. Collaborate with leaders to ensure alignment with business needs a...
1 week ago
Electronic Security Systems Engineer
$88K - $154K *
Engineer innovative Electronic Security Systems solutions for diverse clients, guiding projects from concept to construction. Collaborate with teams to ensure compliance with specifications and delive...
1 week ago
Process Improvement Consultant-Financial Services Facility Construction Program
$100K - $120K *
Transform business operations by identifying improvement opportunities, optimizing processes, and driving sustainable outcomes. Collaborate with stakeholders to enhance performance and support organiz...
1 week ago
Labor & Employment Counsel-Remote
$110K - $130K *
Drive impactful employment law solutions as a Virtual Office Counsel, managing administrative charges and litigation while collaborating with a skilled legal team in a flexible, remote environment foc...
Reposted 1 week ago
$80K - $90K *
Transform your marketing career by driving product strategies and campaigns. Collaborate with cross-functional teams to create compelling messaging and targeted programs that enhance customer engageme...
1 week ago
Account Executive, Mid Market (TOLA)
$152K - $190K *
Engage with mid-sized customers to drive IoT solutions, managing complex sales cycles and building relationships with key stakeholders. Your efforts will directly impact industries that keep our world...
1 week ago
$85K - $100K *
Drive financial excellence by owning month-end close, reconciliations, and management reporting. Collaborate with leadership to enhance processes and ERP systems, ensuring accuracy and compliance as t...
1 week ago
Manager, Value & Access Analytics - GTN Forensics - U.S. Remote
$124K - $169K *
Optimize cross-portfolio analytics to enhance Gross-to-Net performance, identify anomalies, and drive process improvements. Collaborate with diverse teams to deliver actionable insights and scalable r...
1 week ago
Senior Group Funding Associate
$83K *
Engage with group leaders to enhance fundraising efforts, ensuring compliance and support. Manage administrative functions, track spending, and foster collaboration across departments while promoting...
1 week ago
Control Systems Integrator III - Food & Beverage
$95K - $115K *
Transform manufacturing processes by designing and implementing advanced PLC/HMI control systems for food and beverage plants, ensuring optimal performance and efficiency through innovative automation...
1 week ago
$100K - $300K *
Unlock potential by driving enterprise growth in non-commercial foodservice technology. Own the full sales lifecycle, engage stakeholders, and deliver tailored solutions that enhance operational effic...
1 week ago
Control Systems Integrator III
$95K - $115K *
Unlock your potential by developing innovative control systems for diverse industries. Collaborate with clients to solve complex manufacturing challenges through automation and controls, ensuring effi...
1 week ago
Sr. Clinical Account Executive - Oncology - Jackson, MS
$110K - $130K *
Join a dynamic team to drive the launch of a groundbreaking oncology drug. Leverage your pharmaceutical sales expertise to build relationships with healthcare professionals and key stakeholders, ensur...
1 week ago
Sr. Clinical Account Executive - Oncology - Jackson, MS
$110K - $130K *
Drive the launch and adoption of a groundbreaking oncology drug by building strategic relationships with healthcare professionals and key stakeholders. Leverage your pharmaceutical sales expertise to...
1 week ago
Associate Director, Regulatory Science
$177K - $221K *
Champion regulatory excellence by leading cross-functional teams, ensuring compliance, and driving successful oncology drug development through strategic planning and expert guidance...
1 week ago
Manager - Software Development Engineering S 4D
$80K - $100K *
Unlock potential by leading a dynamic team of developers to deliver high-quality software solutions, collaborating with stakeholders, and driving strategic project initiatives while fostering a cultur...
1 week ago
Principal Quality Assurance Specialist, External Manufacturing
$150K - $190K *
Champion quality assurance excellence in GMP for drug substance and products, overseeing compliance and methodologies. Collaborate to ensure regulatory adherence while maintaining operational efficien...
Reposted 1 week ago
$109K - $145K *
Contribute to the development of a cloud storage solution, designing and delivering features for a medical imaging platform. Collaborate within an Agile team, taking ownership of the development lifec...
1 week ago
$80K - $90K *
Join a dynamic team to drive product marketing and ABM strategies, enhancing customer engagement and market presence through compelling messaging and targeted campaigns that foster growth and awarenes...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.