Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
Senior Data Scientist, Safety Enforcement
$190K - $267K *
Transform safety enforcement through data science by developing models and systems that detect and mitigate abuse. Collaborate across teams to translate policies into actionable insights, ensuring eff...
1 week ago
$120K - $170K *
Transform enterprise software systems by leading design and development efforts, ensuring scalable, secure applications that meet federal mission needs while mentoring engineers and driving best pract...
1 week ago
$77K - $85K *
Join a team that's dedicated to delivering high-quality, patient-centered therapy. Collaborate with peers to develop individualized care plans while enjoying competitive compensation and robust profes...
1 week ago
Merchandising Sourcing & Production Manager
$80K - $95K *
Drive the branded merchandise function, overseeing vendor sourcing, production management, and budget accountability. Ensure timely delivery and quality control while collaborating cross-functionally...
1 week ago
Regional Business Manager - East Region
$110K - $130K *
Lead the charge in driving regional sales growth by developing strategic plans, managing budgets, and fostering strong customer relationships. Collaborate with cross-functional teams to optimize perfo...
1 week ago
$75K - $110K *
Optimize the claims resolution process for commercial property and casualty claims. Collaborate with internal teams and stakeholders to enhance claims handling efficiency and effective communication...
Reposted 1 week ago
Senior Software Engineer, Open Harness Engineering
$184K - $356K *
Elevate the future of autonomous software systems by building and optimizing AI agent evaluation frameworks, enhancing usability, reliability, and performance with a collaborative engineering team ded...
Reposted 1 week ago
$125K - $150K *
Drive client engagement and solution development in digital banking, leveraging expertise in banking technology and pre-sales. Collaborate with teams to deliver tailored solutions and impactful demons...
1 week ago
IT Business Operations Manager
$80K - $95K *
Optimize IT operations by managing vendor relationships, contracts, and financial processes. Ensure compliance and efficiency in technology investments while coordinating audits and risk assessments t...
1 week ago
$100K - $120K *
Champion innovation by leading software engineering teams to modernize and deliver technology solutions. Oversee development practices, manage resources, and ensure alignment with business objectives...
1 week ago
Oracle Managed Services Client Director
$150K - $180K *
Empower growth by leading Oracle Managed Services sales and strategy. Drive new business, build executive relationships, and enhance service offerings while collaborating with cross-functional teams t...
1 week ago
Oracle HCM Technical Architect
$120K - $145K *
Transform client experiences by leading the design and implementation of Oracle HCM Cloud solutions. Collaborate with teams to ensure scalable, reliable, and high-performance technical architectures t...
1 week ago
Oracle Program Manager - CX, ERP, HCM & Release Managementransitions
$120K - $145K *
Grow your career with a dynamic role leading Oracle Cloud transformation programs. Oversee multiple projects across CX, ERP, and HCM platforms, ensuring alignment with business objectives while managi...
1 week ago
Oracle HCM Principal Consultant- Core HR
$110K - $130K *
Drive successful Oracle Cloud HCM implementations by leading Core HR solutions, collaborating with stakeholders, and ensuring best practices for HR operations. Provide functional leadership and mentor...
1 week ago
$110K - $130K *
Empower a team of engineers to enhance distribution systems, oversee operations, and innovate solutions. Collaborate with contractors and manage resources effectively to ensure efficient service deliv...
1 week ago
Director, Technical Program Management, Ad Tech
$162K - $228K *
Transform the Ad Tech landscape by leading cross-functional teams to ensure seamless delivery and execution of complex technology portfolios, driving strategic initiatives and fostering collaboration...
1 week ago
Regional Sales Director - Austin
$180K - $215K *
Drive regional success by leading launch execution and building high-performing teams. Foster customer relationships and ensure alignment with corporate goals in a fast-paced, entrepreneurial environm...
1 week ago
Regional Sales Director - Milwaukee
$180K - $215K *
Transform your career by leading regional sales efforts for a groundbreaking product. Drive performance, build a high-performing team, and engage with key healthcare providers in a fast-paced, entrepr...
1 week ago
Regional Sales Director - Phoenix
$180K - $215K *
Transform regional sales performance by leading a high-impact team, executing strategic launches, and fostering key customer relationships in a dynamic, fast-paced environment. Drive accountability an...
1 week ago
Regional Sales Director - Washington D.C.
$180K - $215K *
Shape the future of healthcare by leading regional sales efforts, driving product launch success, and building high-performing teams. Collaborate cross-functionally to achieve sales goals and foster s...
1 week ago
$80K - $133K *
Champion innovative solutions by collaborating with cross-functional teams to develop scalable, cloud-native applications. Leverage your full-stack expertise to modernize systems and deliver high-valu...
1 week ago
Account Manager- Client Success
$80K - $85K *
Grow your career with a dynamic team focused on client success, managing relationships, and delivering tailored solutions. Drive satisfaction and retention while collaborating across departments to en...
1 week ago
Head of Fertility Sales & Business Development
$150K - $180K *
Lead national physician engagement and business development for a fertility pharmacy, managing a multi-layered team to drive growth and build executive relationships across clinics and provider networ...
1 week ago
Lease Connectivity Engineer, Data Center Infrastructure
$120K - $145K *
Join a dynamic team to lead connectivity projects for leased data centers, ensuring compliance with standards and managing cross-functional collaboration from site assessment to operational handoff. D...
1 week ago
Plasma Protein Sales Specialist (CA, AZ, NV, OR, WA, ID, MT)
$85K - $117K *
Join a team that's redefining clinical diagnostics by expanding our plasma protein portfolio. Drive new equipment placements and enhance assay utilization across a diverse territory while fostering st...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.