Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,974

Sort By: Relevance

$80K - $95K *

Join a dynamic team to manage outsourced finance and accounting engagements, ensuring client satisfaction and financial performance. Leverage your expertise in government accounting and technology to...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$172K - $215K *

Drive the execution of solar construction projects by leading a skilled team, ensuring compliance with safety standards, and optimizing drilling operations for stable foundations. Collaborate with sta...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $100K *

Partner with us to enhance client relationships and optimize account management. Drive operational strategies, support sales pursuits, and collaborate with leaders to improve performance and transpare...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$78K - $131K *

Inspire growth by partnering with leaders to design impactful learning experiences that enhance performance across teams. Drive initiatives that empower employees to achieve their goals and improve pr...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Join a team that's dedicated to enhancing technical enablement for sales and engineering roles. You'll develop scalable training programs, manage onboarding, and create hands-on resources to ensure fl...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Drive the design, build, testing, and support of applications, ensuring optimal functionality and user satisfaction while collaborating with interdisciplinary teams to enhance workflows and resolve co...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$119K - $190K *

Champion ABB's growth in the Pharmaceutical & Biotechnology sector by developing strategies, building executive relationships, and identifying market opportunities to drive sales and enhance customer...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$82K - $182K *

Lead strategic initiatives by connecting technology investments to business goals, ensuring effective governance and measurable outcomes. Collaborate cross-functionally to enhance operational efficien...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by leading product strategy for patient recruitment, enhancing engagement and operational efficiency. Collaborate with cross-functional teams to drive measurable outcomes and improve...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$102K - $149K *

Drive growth by identifying new business opportunities in the Water industries. Collaborate with cross-functional teams to implement strategies that enhance customer relationships and support sustaina...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$95K - $115K *

Lead and develop a high-performing team to expand behavioral healthcare access. Drive regional referral growth through strategic partnerships, data-driven decision-making, and effective outreach while...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Drive operational excellence by leading the S&OP strategy, aligning resources with business goals, and optimizing capacity planning across the network to enhance efficiency and service delivery...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $300K *

Partner with us to accelerate sales by expertly closing high-ticket B2B deals. Utilize a structured two-call system to connect with Amazon brand owners and drive significant revenue growth in a fast-p...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $220K *

Shape your career in a supportive endodontic practice, providing specialized care across multiple locations. Collaborate with experienced colleagues and build lasting relationships while focusing on p...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Drive supply chain excellence by leading procurement, co-manufacturing, and inventory management. Ensure product availability and cost efficiency while fostering cross-functional collaboration in a fa...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$71K - $113K *

Engineer innovative ERP solutions by customizing modules, integrating features, and enhancing system performance. Collaborate with stakeholders to align business objectives with technical capabilities...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$83K - $124K *

Unlock potential by leading the design and implementation of CI/CD pipelines, enhancing software delivery and operational stability for enterprise applications while collaborating with cross-functiona...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$116K - $125K *

Elevate cybersecurity measures by designing and implementing robust controls for enterprise applications and infrastructure. Collaborate with cross-functional teams to ensure compliance with federal s...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$105K - $157K *

Drive the vision and strategy for Sales and Service GTM systems, leading cross-functional initiatives and optimizing Salesforce technologies to enhance operational efficiency and modernize legacy syst...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$130K *

Take ownership of driving growth within our SMB customer base by leading a high-performing sales team. Focus on expanding wallet share and deepening relationships through strategic selling of our solu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$87K - $157K *

Join a dynamic team to develop and enhance clinical systems, ensuring compliance with NIH standards. Collaborate with cross-functional teams to troubleshoot and implement solutions that improve health...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$83K - $155K *

Contribute to the success of hygienic sensors by owning product strategy, collaborating with engineering, and driving market insights into actionable requirements. Lead product launches and manage lif...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$240K - $275K *

Drive premium growth by leading broker distribution strategies, building partnerships, and enhancing AI-driven capabilities. Oversee team development and market representation to scale operations and...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$150K - $170K *

Support our Legal team by managing the contract lifecycle, drafting agreements, and ensuring compliance. Collaborate with the Supply team to enhance contracting processes and infrastructure in a fast...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $187K *

Transform client relationships and drive business development in data analytics. Collaborate with internal teams to ensure service alignment, manage account planning, and track performance metrics to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.