Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
Sr. Associate Actuary - Healthcare
$120K - $140K *
Elevate healthcare consulting by leading complex actuarial projects, developing financial models, and advising clients on policy impacts. Collaborate with teams to analyze data, mentor analysts, and e...
1 week ago
Project Leadership (Clinical Trials) - Homebased
$110K - $130K *
Champion global clinical trials by leading project teams to deliver excellence on time and within budget, ensuring high-quality outcomes that exceed client expectations in the biotech and pharma secto...
1 week ago
Associate Account Director - Healthcare & Pharmaceutical Exhibit Activations - Remote
$80K - $95K *
Join a dynamic team as you drive account retention and growth, collaborating with creative and operations departments to deliver exceptional client service and innovative solutions while managing proj...
1 week ago
Senior Backend Engineer (Integrations & Platform)
$150K - $185K *
Unlock potential by designing and maintaining scalable backend systems for complex data integrations. Collaborate with partners to enhance operational efficiency and reliability, ensuring seamless dat...
1 week ago
$105K - $125K *
Take ownership of safety initiatives across multiple construction sites, ensuring compliance and fostering a culture of safety. Collaborate with teams to educate and implement best practices while con...
1 week ago
$110K - $130K *
Drive medication therapy management services by conducting comprehensive reviews and consultations. Collaborate with the MTM product team to ensure accurate data entry and enhance patient care through...
1 week ago
$125K - $150K *
Join a team that's redefining enterprise sales by engaging C-suite stakeholders in Tier 1 banks and credit unions. Drive complex sales cycles, build strategic relationships, and deliver tailored solut...
1 week ago
RCM Implementation Consultant - EHR/SaaS/Healthcare IT/PT
$80K - $95K *
Manage the implementation process for clients in Revenue Cycle Management, ensuring efficient setup and optimization of billing workflows. Serve as the primary expert, guiding healthcare organizations...
1 week ago
$80K - $95K *
Engineer innovative civil designs for utility-scale solar and battery projects. Collaborate with multidisciplinary teams to create site layouts, grading, and drainage plans, ensuring compliance and ef...
1 week ago
Manager, Product Trainer Neuro - Immunology- Multiple Positions
$126K - $234K *
Unlock potential by designing and delivering innovative training solutions for customer-facing teams, enhancing product knowledge and engagement skills across diverse therapeutic areas and roles...
1 week ago
$115K - $140K *
Join us to drive revenue growth by engaging senior finance leaders, executing full-cycle sales, and delivering tailored software solutions that address financial challenges and enhance operational eff...
1 week ago
Forward Deployed Engineer (TypeScript + AI) - Remote - USA
$120K - $140K *
Unlock your potential as a Forward Deployed Engineer, bridging AI solutions with enterprise needs. Collaborate closely with clients to architect and implement robust systems, ensuring real-world appli...
1 week ago
$100K - $150K *
Transform the mobile landscape by architecting a scalable React Native application. Lead engineering standards, mentor developers, and integrate enterprise systems to enhance user experience across iO...
Reposted 1 week ago
Senior Product Designer, Logistics
$110K - $130K *
Grow your career with a dynamic design role focused on transforming complex supply chain systems into intuitive user experiences. Collaborate with teams to enhance operational efficiency and drive imp...
1 week ago
Field Marketing Manager- Public Sector (US)
$110K - $130K *
Join the charge in shaping CoreView's Federal market presence by leading strategic field marketing initiatives, enhancing brand awareness, and driving lead generation campaigns to establish a robust p...
1 week ago
$180K - $200K *
Elevate healthcare technology by owning mobile and web apps that enhance clinician workflows. Drive product direction, prioritize initiatives, and ensure patient safety while leveraging AI to improve...
1 week ago
Senior Machine learning Engineer
$162K - $258K *
Drive the design and implementation of cutting-edge GenAI solutions, leading the development of LLM capabilities and ML pipelines to enhance insurance workflows and deliver impactful outcomes for cust...
1 week ago
$150K - $180K *
Transform the infrastructure landscape by leading Site Reliability Engineering and platform architecture for global expansion, ensuring reliability, cost efficiency, and compliance across multiple ser...
1 week ago
Senior Backend Engineer/Staff Engineer
$165K - $210K *
Drive the technical vision for complex systems, leading cross-team initiatives and enhancing engineering standards. Own reliability and scalability of core infrastructure while mentoring engineers and...
1 week ago
Consultant, Technical FedRAMP Assessment
$80K - $134K *
Elevate compliance standards by conducting detailed FedRAMP assessments, analyzing technical artifacts, and collaborating with clients to ensure security controls are effectively implemented and docum...
1 week ago
$106K - $114K *
Lead the charge in driving strategic partnerships, managing budgets, and optimizing performance. Collaborate cross-functionally to enhance partner success and deliver impactful training programs, ensu...
1 week ago
Engineering Manager, Core Engineering
$171K - $248K *
Lead a dynamic engineering team to enhance infrastructure and networking, driving user-focused product development while fostering collaboration and operational excellence across the organization...
1 week ago
$150K - $200K *
Develop and maintain robust data pipelines and models, collaborating with cross-functional teams to enhance data practices and ensure quality. Drive modernization efforts in data engineering, optimizi...
1 week ago
Director of Client Success - Revenue Cycle Management - (MIDWEST)
$110K - $130K *
Drive client success by managing relationships, enhancing satisfaction, and identifying growth opportunities. Collaborate with internal teams to deliver exceptional service and exceed client expectati...
1 week ago
$80K - $95K *
Empower healthcare technology by enhancing clinical systems and integrations. Collaborate with IT and business stakeholders to optimize workflows, manage projects, and ensure system performance across...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.