Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
$110K - $130K *
Join a team that's shaping intuitive AI experiences through user-centered design. Collaborate with cross-functional teams to translate complex AI capabilities into accessible solutions that drive busi...
1 week ago
Key Account Manager- Packaging & Labeling
$90K - $130K *
Shape the future of our sales strategy by developing plans that align with business objectives and drive measurable goals, ensuring effective implementation and collaboration across regional teams to...
Reposted 1 week ago
Senior Regulatory Affairs Specialist
$110K - $130K *
Shape the future of health technology by driving regulatory strategies for innovative lab testing, imaging, and AI products. Collaborate with cross-functional teams to ensure compliance and accelerate...
1 week ago
Senior Manager, PR & Communications
$151K - $177K *
Join a dynamic team to shape compelling narratives at the intersection of technology and consumer engagement. Drive impactful PR initiatives, build media relationships, and elevate brand visibility th...
1 week ago
$130K - $150K *
Shape the future of communication by leading consultative sales cycles across mid-market and enterprise segments. Drive full sales processes with a focus on value-based selling and collaboration with...
1 week ago
$100K - $120K *
Drive the development and support of healthcare interfaces and FHIR APIs, ensuring secure clinical data exchange. Collaborate with teams to implement solutions that enhance health information interope...
1 week ago
$95K - $115K *
Take ownership of developing and supporting healthcare interfaces and FHIR APIs for a statewide Health Information Exchange, ensuring secure and reliable clinical data exchange across multiple healthc...
1 week ago
$100K - $120K *
Empower your career by developing secure healthcare interfaces and FHIR APIs. Collaborate on a statewide Health Information Exchange, ensuring reliable clinical data exchange while supporting diverse...
1 week ago
Aeroderivative Senior Controls Technician (West Region)
$77K - $129K *
Join a team that's dedicated to maintaining and enhancing instrumentation and controls systems. Leverage your expertise to troubleshoot, repair, and upgrade equipment while ensuring safety and complia...
1 week ago
Senior Director, Liquid Processing & Capital Projects Engineering
$176K - $205K *
Lead the charge in executing complex capital projects and liquid processing strategies. Drive innovation and efficiency across manufacturing networks while mentoring engineering teams and ensuring pro...
1 week ago
$110K - $120K *
Elevate pricing strategies by analyzing data, guiding deals, and enhancing profitability. Collaborate across teams to drive smarter pricing decisions and improve seller experiences, ensuring competiti...
1 week ago
$250K - $500K+*
Drive innovation by collaborating with hardware teams to enhance tools, evolve compilers, and improve developer experiences, ensuring efficient and effective hardware design processes...
1 week ago
$66K - $102K *
Lead the charge in delivering innovative SAP MDG solutions, leveraging your expertise to design, implement, and optimize data governance processes. Collaborate with cross-functional teams to drive imp...
1 week ago
Risk Adjustment Operations Senior Project Analyst
$103K - $121K *
Champion project success by building pacing trackers and forecasting models, collaborating with Finance to enhance capacity planning and resource allocation, while providing leadership with real-time...
1 week ago
Product Management Lead, Communication Platform
$180K - $220K *
Lead the charge in shaping effective member communication strategies. Oversee product development to integrate robust data-driven solutions that enhance customer engagement and drive measurable busine...
Reposted 1 week ago
General Liability Claim Consultant/Specialist - Personal and Advertising Injury Liability
$84K - $161K *
Lead the management of complex Personal and Advertising Injury Liability claims, ensuring timely resolution and strategic oversight. Collaborate with legal counsel and stakeholders to achieve optimal...
1 week ago
Senior Manager, Events & Field Marketing
$110K - $130K *
Lead the charge in executing North America's largest trade shows and events. Collaborate with sales and marketing teams to drive strategy, manage budgets, and enhance brand presence, while ensuring al...
1 week ago
MTE - Sales Manager, LPG (East)
$90K - $110K *
Elevate your career by driving LPG tank sales across the Eastern US. Build lasting relationships with propane marketers and distributors while executing a results-driven commercial strategy to achieve...
1 week ago
Product Management Senior Advisor
$113K - $188K *
Champion the development of innovative tools for customer service teams, enhancing agent efficiency and service quality. Collaborate across departments to drive product strategy, leveraging data and u...
1 week ago
$120K - $145K *
Lead the charge in transforming data analytics for critical enterprise systems. Drive innovative solutions, manage complex data architectures, and collaborate with diverse teams to enhance data-driven...
1 week ago
Senior Channel Partnerships Manager
$110K - $130K *
Elevate partner success by managing strategic mid-market and enterprise relationships. Drive revenue growth through effective onboarding, enablement, and co-selling, while collaborating cross-function...
1 week ago
Forward Deployed Engineer I (Remote, US)
$160K - $180K *
Join a team that's dedicated to delivering seamless technical solutions for clients. You'll scope, implement, and maintain risk screening and data integration workflows, ensuring optimal performance a...
1 week ago
21GRAMS- Senior Project Manager
$110K - $115K *
Join a team that's redefining healthcare project management. Lead integrated initiatives, mentor talent, and drive excellence across diverse campaigns while fostering collaboration and innovation in a...
1 week ago
Senior Director, Real Estate & Workplace Strategy
$190K - $210K *
Advance our real estate strategy by leading portfolio planning, workplace design, and data analysis. Collaborate with internal teams and external partners to optimize office spaces, enhance employee e...
1 week ago
Senior Marketing Manager, Lifecycle & Growth
$90K - $120K *
Join a dynamic team to drive customer activation and retention strategies across the prescription lifecycle. Collaborate cross-functionally to optimize customer journeys and deliver measurable growth...
Reposted 1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.