Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,974

Sort By: Relevance

$88K - $120K *

Unlock potential by leading sales teams to drive revenue growth and enhance client relationships. Collaborate across departments to implement strategic plans, ensuring customer success and market expa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$134K - $231K *

Shape the future of global supply chain operations by providing strategic legal support, drafting contracts, and ensuring compliance with environmental and safety regulations. Collaborate across funct...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$84K - $135K *

Accelerate your career as you build key relationships and drive sales success in the construction supplies sector, achieving ambitious targets while supporting distributor partners in a dynamic field...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$109K - $143K *

Drive procurement excellence by developing strategies that enhance cost efficiency and quality. Lead cross-functional teams to implement innovative solutions, ensuring alignment with project objective...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$104K - $259K *

Engage in cutting-edge adversary research to lead a team in identifying and analyzing sophisticated cyber threats. Drive strategic initiatives, enhance security outcomes, and communicate findings to d...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$120K - $145K *

Drive the transformation of AI solutions by developing, deploying, and optimizing machine learning models. Collaborate with stakeholders to create innovative applications that enhance patient care whi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$109K - $173K *

Elevate your career by partnering with us to enhance financial forecasting and reporting processes. Leverage your analytical skills to improve business intelligence systems and drive key performance i...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $136K *

Transform fleet maintenance operations by leading strategic initiatives, optimizing performance, and ensuring compliance across multiple locations. Drive efficiency and reliability while fostering a c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Transportation

$85K - $92K *

Join our team to enhance healthcare quality through precise coding audits, mentoring coders, and driving process improvements. Your expertise will help shape compliance and accuracy in outpatient serv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$135K - $160K *

Champion cloud security excellence by engineering robust solutions across AWS and GCP. Drive vulnerability remediation, system hardening, and compliance for federal clients while mentoring junior engi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Advance your career by leading HR strategies that enhance employee engagement, drive talent acquisition, and ensure compliance. Collaborate with leadership to optimize workforce planning and foster a...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$170K - $222K *

Drive strategic transformation initiatives across Product, GTM, and Operations. Lead cross-functional teams, manage complex portfolios, and deliver measurable results while fostering clarity and accou...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$168K - $219K *

Join a dynamic team as a Sr. Solutions Engineer, leveraging your expertise to solve complex business challenges for mid-market customers, driving impactful solutions and fostering collaboration to enh...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Shape the future of enrichment programs by driving strategy, execution, and operational excellence across multiple sites, ensuring impactful experiences for families and children while achieving finan...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$116K - $155K *

Shape the future of HR technology by leading strategy, governance, and optimization of HRIS. Drive operational excellence, enhance user experience, and ensure compliance while managing a high-performi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$115K - $125K *

Drive the development and enhancement of enterprise planning solutions globally, focusing on Anaplan and supporting FP&A, Sales, and Production Planning initiatives. Collaborate with teams to analyze...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Drive your career forward by leveraging advanced AI to enhance pricing programs. Join a new, dynamic team focused on building evaluations that ensure AI delivers value and accuracy, shaping the future...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $128K *

Elevate cybersecurity operations by monitoring threats, analyzing network traffic, and coordinating incident responses. Collaborate with teams to enhance security measures and mentor junior analysts w...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$66K - $106K *

Join a dynamic team to design and implement secure identity solutions using Okta, ensuring compliance with DoD standards while enhancing authentication processes across high-visibility systems in a fu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$79K - $91K *

Transform healthcare delivery by leading the RN UM Team, ensuring timely care decisions and maintaining documentation quality while fostering a culture of clinical excellence and accountability...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $135K *

Join our team as a Telehealth Pharmacist, where you'll enhance member health through Medication Therapy Management and clinical outreach programs, ensuring high-quality care and compliance with indust...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $179K *

Lead quality initiatives by optimizing test strategies and automation processes. Collaborate with cross-functional teams to ensure high-quality software delivery while mentoring engineers and driving...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$94K - $179K *

Lead the charge in managing complex projects from inception to completion, ensuring timely delivery and stakeholder satisfaction while guiding cross-functional teams through the project lifecycle...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$101K - $204K *

Help us shape compensation strategies that attract and retain top talent. As a Senior Compensation Partner, you'll collaborate with leaders to navigate complex compensation challenges and enhance our...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$92K - $158K *

Lead the charge in cybersecurity compliance for an AWS-hosted Army application, managing vulnerability findings and security scanning while collaborating with technical teams to ensure robust security...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.