Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
New Business Sales Executive - Western Territory
$100K - $120K *
Drive revenue growth by cultivating relationships and managing the full-cycle sales process in the healthcare technology sector. Utilize AI-driven solutions to enhance client performance and deliver v...
1 week ago
$80K - $95K *
Join a team that's transforming client websites into growth engines through data-driven conversion rate optimization. Collaborate with cross-functional experts to analyze user behavior, run A/B tests...
1 week ago
$100K - $120K *
Optimize customer engagement by leveraging technical expertise to drive sales, enhance relationships, and expand market share for pneumatic and control systems. Collaborate with teams to deliver tailo...
1 week ago
Senior Manager / Associate Director, Medical Information
$165K - $210K *
Drive the Medical Information strategy for infigratinib, ensuring high-quality, compliant content delivery. Collaborate cross-functionally to support scientific exchange and operational excellence in...
1 week ago
$80K - $95K *
Transform customer relationships and drive revenue growth by managing account strategies, identifying upsell opportunities, and collaborating with cross-functional teams to enhance product adoption an...
Reposted 1 week ago
$120K - $175K *
Pioneer insights at the intersection of Sales, Marketing, and CS by owning and enhancing analytical infrastructure to generate decision-ready insights that drive growth in a dynamic, fast-paced enviro...
Reposted 1 week ago
Sr. Advisor, Molecular Pharmacology - Neuroscience
$129K - $231K *
Reimagine drug discovery as you lead molecular pharmacology efforts in neuroscience. Collaborate across teams to develop strategies, interpret data, and advance innovative therapies for sleep-wake dis...
Reposted 1 week ago
$80K - $105K *
Join a specialized team to evaluate biological research, ensuring safety against misuse. Utilize your expertise to distinguish legitimate science from potential threats, contributing to AI safety and...
1 week ago
Senior Staff Engineer, Design Systems
$135K - $160K *
Join a dynamic team to architect and implement a next-gen Design System, ensuring consistent, accessible experiences across products. Collaborate with cross-functional teams to drive technical alignme...
1 week ago
Director, Access Strategy & Marketing
$201K - $251K *
Elevate access strategies and marketing initiatives for oncology products, focusing on non-clinical value propositions. Collaborate cross-functionally to ensure successful product launches and effecti...
1 week ago
Executive Director Access Services - Immunology
$255K - $424K *
Lead the development and execution of Immunology access services strategy, ensuring seamless patient and provider experiences. Collaborate cross-functionally to enhance reimbursement initiatives and d...
1 week ago
$142K - $160K *
Champion privacy compliance in the Neurology therapeutic area, providing expert guidance on data protection, contract negotiation, and training. Collaborate with cross-functional teams to ensure adher...
1 week ago
Territory Sales Representative, Dental Implants
$70K - $150K *
Drive growth in oral surgery practices by building relationships, pursuing new sales opportunities, and achieving targets. Leverage your sales expertise to deliver exceptional customer service and sup...
1 week ago
Patient Access Liaison - Remote
$110K - $130K *
Join us to minimize access barriers for patients and providers, executing market access plans across multiple states. Collaborate with healthcare professionals to resolve reimbursement issues and enha...
1 week ago
$150K - $350K *
Join a team that's building scalable, high-performance backend systems using TypeScript. Collaborate across functions to optimize trading solutions and tackle complex challenges in the blockchain spac...
1 week ago
Oracle Utilities Field Service Solution Architect
$120K - $145K *
Empower your career by leading the design and implementation of Oracle Field Service solutions for utility organizations. Collaborate with stakeholders to enhance operational performance and customer...
1 week ago
Enterprise Customer Success Manager
$110K - $130K *
Unlock potential by overseeing a portfolio of enterprise accounts, fostering strategic partnerships, and driving user engagement to achieve measurable outcomes. Collaborate with internal teams to deli...
1 week ago
Sr. Director, Marketing Strategy, Analytics & Innovation
$227K - $335K *
Empower growth through strategic marketing leadership, leveraging data insights to drive customer engagement and revenue. Build and mentor a high-performing team to transform analytics into actionable...
1 week ago
Associate Director - Clinical Operations - Healthcare
$155K - $259K *
Transform healthcare performance by leading integrated optimization programs that enhance clinical, operational, and financial outcomes for hospitals and health systems. Drive measurable results throu...
1 week ago
$110K - $130K *
Shape the future of product design by transforming concepts into high-fidelity experiences. Collaborate with cross-functional teams to enhance user interactions through innovative prototyping and AI-a...
Reposted 1 week ago
Senior Director, Business Development
$150K - $180K *
Join a team that's driving growth in the biopharmaceutical sector by developing strategic business relationships, prospecting new clients, and leading sales initiatives to achieve organizational objec...
1 week ago
Oracle Principal Pre-Sales & Delivery Architect
$150K - $180K *
Unlock the potential of Oracle solutions by leading multi-engagement pre-sales and delivery efforts. Drive customer adoption and value through strategic solution design, ensuring seamless integration...
1 week ago
21GRAMS- Group Copy Supervisor
$135K - $145K *
Partner with us to elevate healthcare communications by crafting compelling copy for HCP campaigns. Lead creative initiatives, collaborate with cross-functional teams, and ensure brand consistency acr...
1 week ago
Infrastructure Lead, DoD / DoW
$163K - $203K *
Shape the future of defense infrastructure by leading technical engagements and ensuring successful project execution. Collaborate with stakeholders to deliver innovative solutions that meet mission-c...
1 week ago
Capital Projects Procurement Specialist I-Sr Staff
$95K - $115K *
Transform capital project procurement by leading commercial strategies and supplier management. Collaborate across business units to enhance safety, cost efficiency, and project delivery while ensurin...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.