Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
$143K - $208K *
Join a dynamic team as you lead enterprise-wide manufacturing strategy, ensuring performance and scalability across multiple facilities while driving cross-functional collaboration and continuous impr...
1 week ago
$68K - $97K *
Unlock potential by delivering innovative designs that elevate brand identity. Collaborate on strategic campaigns, mentor junior designers, and lead complex projects from concept to execution, all whi...
1 week ago
Director NovaOS Product Owner - 1 of 4
$194K - $361K *
Lead the development of innovative NovaOS capabilities, ensuring alignment with business goals and driving continuous improvement through collaboration across cross-functional teams. Deliver measurabl...
Reposted 1 week ago
$100K - $120K *
Elevate your career by resolving complex commercial property losses, managing national accounts, and providing expert insights. Collaborate with diverse stakeholders while ensuring compliance and main...
1 week ago
$133K - $184K *
Join a team that's enhancing threat detection and response capabilities. As a hands-on technical leader, you'll drive security initiatives across cloud, infrastructure, and identity platforms, while m...
1 week ago
Regional Account Manager, SLED
$80K - $95K *
Elevate your career by driving sales in the SLED sector. Collaborate with partners, manage accounts, and execute strategies to exceed quotas while building lasting relationships with state agencies. Y...
1 week ago
Senior Domain Architect (Data Management)
$129K - $210K *
Empower organizations by designing scalable data management solutions, collaborating with customers and partners to drive adoption and success. Act as a key technical advisor, bridging teams to ensure...
1 week ago
Senior Software Engineer, AI Developer Experience
$135K - $160K *
Lead the charge in building AI-powered engineering systems that enhance developer workflows, ensuring reliability and ease of adoption for engineers. Collaborate with teams to create innovative soluti...
1 week ago
Test Manager, Professional Services
$132K - $198K *
Elevate quality assurance practices by leading test strategy and execution for customer implementations. Collaborate with teams to enhance product quality, mitigate risks, and establish scalable testi...
Reposted 1 week ago
Medical Science Liaison /Senior Medical Science Liaison - Specialty - Northeast Region
$162K - $203K *
Transform your career by engaging with key opinion leaders in Urology and Women's Health. Leverage your scientific expertise to drive medical strategies and foster relationships that enhance product u...
1 week ago
Medical Science Liaison - Ophthalmology/Endocrinology - AL, LA, AR, MS
$156K - $212K *
Engage with the medical community as a scientific liaison, fostering relationships with key experts and clinicians. Communicate vital scientific information and collaborate across teams to address unm...
1 week ago
Lead Consultant CDH Implementation
$105K - $149K *
Transform complex Consumer-Directed Health implementations for major employers. Lead strategy, execution, and client engagement while serving as a subject-matter expert to ensure operational excellenc...
1 week ago
Strategic Business Developer 5
$120K - $145K *
Shape the future of avionics sales by leading business development efforts, engaging military and commercial aerospace customers, and driving strategic growth in the Americas through innovative test s...
1 week ago
Nurse Practitioner - Greenwood/Cleveland Neurology Clinic
$90K - $110K *
Lead the charge in delivering comprehensive patient care as a Nurse Practitioner, collaborating with healthcare teams to ensure effective diagnosis, treatment, and education while maintaining high sta...
1 week ago
Nurse Practitioner - Greenwood/Cleveland Neurology Clinic
$90K - $110K *
Join a dynamic healthcare team to provide comprehensive patient care, ensuring effective diagnosis, treatment, and education. Collaborate with multidisciplinary teams to enhance patient outcomes while...
1 week ago
Nurse Practitioner - Greenwood/Cleveland Neurology Clinic
$90K - $110K *
Advance patient care by examining and treating individuals independently while collaborating with healthcare teams. Utilize your expertise to ensure effective diagnosis, treatment, and education, all...
1 week ago
Director, Technical Product Management
$150K - $180K *
Pioneer the strategy and execution of data platforms and AI products, leading cross-functional teams to enhance commercial life sciences solutions while driving revenue growth and product adoption in...
Reposted 1 week ago
Product Client Success Manager (First Party Casualty)
$78K - $120K *
Transform claims operations as you empower clients by driving adoption of innovative solutions, optimizing processes, and enhancing business outcomes in the First Party Casualty landscape across vario...
Reposted 1 week ago
Dentist - Beachview Family Dental
$125K - $150K *
Lead the charge in delivering exceptional dental care while utilizing cutting-edge technology. Join a dedicated team focused on patient satisfaction and professional growth in a supportive environment...
1 week ago
$81K - $110K *
Lead the transformation of patient care by enhancing utilization review processes, ensuring quality documentation, and collaborating with healthcare teams to optimize clinical outcomes and financial p...
1 week ago
Business Process Improvement & Internal Controls Specialist Department of War (DOW)
$61K - $101K *
Unlock potential by joining a dynamic team focused on financial management, internal controls, and fraud risk. Collaborate with federal clients to enhance processes and drive measurable outcomes in au...
1 week ago
$240K - $300K *
Pioneer a luxury automotive experience as you lead operations, drive sales, and cultivate client relationships in a unique, single-point Porsche dealership. Own the financials and team dynamics while...
1 week ago
Vacation Rental Advisor (Inside Sales)
$55K - $118K *
Champion a consultative sales approach to engage homeowners, guiding them through the partnership process. Leverage inbound leads to drive conversions and manage a dynamic sales pipeline, contributing...
Reposted 1 week ago
Senior Manager, Virtual Fundraising (Remote)
$80K - $95K *
Join a team that's redefining virtual fundraising by leading innovative campaigns that engage diverse audiences, cultivate partnerships, and drive sustainable revenue growth, all while supporting a me...
1 week ago
Enterprise Architect - Data & Employee Systems (Databricks)
$150K - $170K *
Unlock the potential of enterprise data architecture by designing secure, scalable solutions for employee data using Databricks. Collaborate with cross-functional teams to implement governance, compli...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.