Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
Healthcare Customer Success Executive, Sr.
$110K - $130K *
Drive customer success by fostering executive relationships and ensuring retention and growth across a defined portfolio. Leverage strategic insights to translate customer outcomes into measurable bus...
1 week ago
Communications Specialist, Education Systems & Policy
$96K - $102K *
Join a dynamic team to develop and implement strategic communications initiatives that translate complex research into engaging content for diverse audiences, enhancing visibility and impact across ed...
1 week ago
Account Manager, Molecular Diagnostics, QIAstat (Midwest)
$100K - $120K *
Advance healthcare solutions by driving sales of innovative diagnostic instruments. Engage with key stakeholders to promote QIAstat-Dx systems, ensuring successful adoption and customer satisfaction t...
1 week ago
HCP Personal Marketing Lead - Epilepsy
$190K - $214K *
Lead HCP personal promotion strategy, developing and optimizing initiatives that engage healthcare professionals. Collaborate cross-functionally to ensure compliance and effectiveness in promotional t...
1 week ago
Sr. Staff Applied AI Engineer, GTM
$180K - $225K *
Lead the charge in transforming AI strategies into impactful solutions for revenue teams, collaborating closely with GTM leaders to drive innovation and measurable outcomes while enhancing engineering...
1 week ago
21GRAMS- Associate Creative Director, Art
$160K - $180K *
Elevate healthcare creativity by leading innovative campaigns that transform client brands. Collaborate with teams to deliver impactful experiences across digital channels, leveraging insights and eme...
1 week ago
Azure Application Engineering Lead
$125K - $150K *
Join a team that's redefining cloud solutions by architecting and delivering complex Azure engagements. Lead migrations, mentor engineers, and drive innovation while ensuring robust security and gover...
1 week ago
Manager, Customer Engagement (Remote)
$100K - $112K *
Join a team that's transforming customer engagement through innovative product launches. You'll lead cross-functional collaboration, develop training materials, and ensure readiness for market, all wh...
1 week ago
$120K - $145K *
Join the forefront of quality assurance in government logistics. Lead the development and enhancement of a robust Quality Management System across multiple sites, ensuring compliance and operational e...
1 week ago
$76K - $124K *
Engage in foundational sales support, collaborating with Client Account Executives to develop skills in territory strategy, deal mechanics, and enterprise sales, while preparing for a quota-carrying r...
1 week ago
$100K - $120K *
Shape the future of automotive sales by leading a dynamic team, developing strategic initiatives, and engaging directly with clients to enhance their repair processes while achieving ambitious sales t...
1 week ago
$150K - $200K *
Bring your expertise to lead sales strategies and customer development across NCC and VIS product lines, driving profitable growth and enhancing commercial processes while fostering collaboration with...
Reposted 1 week ago
$79K - $109K *
Transform financial operations by owning monthly close processes, ensuring accurate COGS and accruals. Collaborate with leadership to drive data-driven decisions in a dynamic, growth-stage tech enviro...
1 week ago
Account Executive, Enterprise Suite - Financial Services
$124K - $171K *
Accelerate sales growth by managing and qualifying strategic Enterprise Intelligence opportunities. Collaborate with cross-functional teams, ensuring comprehensive engagement and communication to opti...
Reposted 1 week ago
Senior Financial Analyst, Corporate FP&A
$115K - $151K *
Advance your career by leading financial reporting and forecasting efforts. Collaborate across departments to analyze data, streamline processes, and support strategic planning in a dynamic, high-grow...
1 week ago
$112K - $119K *
Unlock new demand by leading our growth marketing strategy through innovative content and partnerships. Collaborate with clinical experts to engage educators and drive product signups across multiple...
1 week ago
Senior Product Manager, Secret Detection and Vulnerability Research
$138K - $165K *
Drive GitLab's Secret Detection and Vulnerability Research efforts to shape security product outcomes. Own the detection lifecycle, ensure content quality, and leverage AI to enhance operational effic...
Reposted 1 week ago
$150K - $180K *
Drive innovation in power systems architecture by collaborating with hyperscalers and partners to develop cutting-edge connector and cable solutions. Lead technical programs, influence strategic objec...
1 week ago
Physician (Diagnostic Radiologist)
$210K - $250K *
Empower patient care through expert image interpretation and guidance in diagnostic radiology. Collaborate on quality assurance, oversee technical standards, and educate staff while ensuring optimal p...
1 week ago
Sales Enablement Program Manager
$110K - $150K *
Lead the charge in enhancing sales performance through targeted enablement initiatives. You'll work closely with diverse sales teams to coach, train, and build effective tools, ensuring impactful and...
Reposted 1 week ago
Specialty Representative/Sr Specialty Representative -Primary Care -Jackson S, MS
$89K - $171K *
Unlock potential by driving sales and building relationships with healthcare professionals. In this role, you'll leverage clinical knowledge to promote products, navigate payer complexities, and achie...
1 week ago
Territory Sales Representative, Implants MIS
$82K - $150K *
Accelerate growth by driving new customer acquisition and expanding market share in the dental implant sector. Leverage a hunter mentality to convert competitive accounts and position value-oriented s...
Reposted 1 week ago
$150K - $220K *
Oversee a specialized team to ensure AI safety in biological research, addressing dual-use risks and providing expert guidance on complex cases while mentoring junior specialists and advising clients...
1 week ago
$83K - $103K *
Redefine delivery performance as the key contact for shipment deviations, ensuring proactive communication and effective escalation. Drive continuous improvement initiatives while analyzing data to en...
1 week ago
$117K - $150K *
Champion your actuarial expertise to drive financial reporting and reserve setting for annuities. Collaborate on high-impact projects, adapt to evolving needs, and enhance reporting models in a dynami...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.