Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,580

Sort By: Relevance

$135K - $220K *

Lead the charge in enhancing security tooling for compliance and cybersecurity. Collaborate with engineering teams to automate security checks, ensuring a robust pipeline that balances speed and secur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$92K - $156K *

Lead the charge in financial reporting and compliance, managing complex accounting processes and driving efficiency. Collaborate with teams to enhance accuracy and support strategic decision-making in...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Drive the success of home inspections at military installations by leading onsite operations, managing field staff, and ensuring seamless communication with military leadership. This role requires ext...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $120K *

Lead the charge in managing on-site construction activities, ensuring compliance with safety, schedule, and quality standards while mentoring teams and driving project success in renewable energy proj...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$235K - $270K *

Join a dynamic team to lead transformative improvements in global supply chain operations, focusing on logistics excellence and strategic initiatives that enhance service, cost efficiency, and operati...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$70K - $150K *

Develop strategic business relationships to drive revenue growth and enhance customer satisfaction. Utilize market insights to create tailored business plans and ensure profitable account management w...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$190K - $240K *

Lead the end-to-end revenue cycle operations, driving improvements in eligibility, coding, and claims management. Collaborate with teams to enhance workflows and ensure accountability, while evaluatin...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $255K *

Grow your career by leading the evolution of a dynamic training program for early-career Solutions Engineers, ensuring high-quality learning experiences and effective deployment into the field while f...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$81K - $111K *

Take ownership of warehouse operations by managing daily activities, optimizing processes, and ensuring compliance with safety standards. Lead a team to enhance efficiency, accuracy, and service quali...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Join a team that's dedicated to advancing Distribution Protection through leadership and innovation. Lead engineers, oversee critical projects, and ensure seamless operations in Power Delivery with a...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$101K - $112K *

Lead the charge in managing complex projects within the Education portfolio, ensuring effective coordination across teams and stakeholders while driving impactful outcomes in higher education and appl...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $95K *

Transform business development strategies by collaborating with sales teams to drive growth in the national market. Leverage your expertise to identify opportunities and support proposal development w...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$88K - $105K *

Drive continuous improvement by leading a team focused on process optimization, quality management, and cost reduction initiatives. Collaborate cross-functionally to enhance operational stability and...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$290K - $340K *

Lead and inspire engineering teams to develop cutting-edge web and AI security solutions. Drive strategy, execution, and organizational health while fostering a culture of innovation and accountabilit...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Elevate security practices by building and managing a comprehensive security program. Collaborate with engineers to identify vulnerabilities, implement automated checks, and ensure robust protection a...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $120K *

Unlock potential by serving as a technical partner to sales, providing expertise in automation solutions. Manage application opportunities, engage with customers, and recommend improvements to align t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$130K - $160K *

Join a team that's dedicated to delivering data-driven solutions for life sciences clients. Leverage your expertise to drive insights, optimize user experiences, and collaborate with cross-functional...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Drive capital project execution and engineering improvements in a manufacturing facility. Lead projects from concept to completion, ensuring adherence to safety, quality, budget, and schedule while en...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$109K - $160K *

Transform your career by managing web production and enhancing user experiences. Collaborate with cross-functional teams to prioritize projects, execute testing roadmaps, and optimize web performance...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$115K - $150K *

Join a team that's dedicated to advancing clean energy by developing and owning plant process simulation models. Collaborate across disciplines to enhance design, operations, and plant dynamics for in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$177K - $221K *

Manage the strategy and execution of access marketing for oncology products, focusing on value propositions for payers and healthcare providers. Collaborate with cross-functional teams to ensure effec...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$211K - $235K *

Drive patient access initiatives by leveraging oncology expertise to navigate reimbursement landscapes, educate stakeholders, and resolve complex access issues, ensuring timely therapy access for pati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$82K - $150K *

Elevate your career by driving growth in the dental implant market. This role focuses on acquiring new customers, expanding market share, and positioning value-driven solutions, requiring a proactive...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $120K *

Drive sales success by building relationships with dental professionals, promoting innovative products, and achieving targets. Leverage your expertise to deliver exceptional customer service and suppo...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Take ownership of the comprehensive tooling process, focusing on design, sourcing, and enhancement to ensure optimal performance and quality in production while leading continuous improvement initiati...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.