Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
$120K - $150K *
Lead the charge in building long-term customer relationships while optimizing operations. As a Business Manager, you'll drive strategic growth, manage key accounts, and collaborate across teams to enh...
1 week ago
Head of Strategic Partnerships
$160K - $200K *
Lead transformative partnerships in the travel industry, driving strategic growth and revenue. Engage with C-suite executives to secure high-impact deals and elevate market positioning through collabo...
1 week ago
Nurse Practitioner or Physician Assistant - Immediate Care-Petal
$90K - $110K *
Empower individuals by providing comprehensive health care services in diverse settings. Utilize your expertise to diagnose, manage illnesses, and promote wellness through education and counseling, en...
1 week ago
Senior Product Operations Manager
$110K - $130K *
Transform product operations by enhancing collaboration across teams and streamlining the launch processes. Utilize data-driven insights and AI to identify bottlenecks and drive efficiency, ensuring s...
Reposted 1 week ago
Director, Patient Financial Services (PFS) - Healthcare CBO
$106K - $176K *
Join a team that's transforming healthcare finance by leading patient financial services operations. Drive revenue cycle improvements, manage billing processes, and enhance compliance while fostering...
1 week ago
$110K - $125K *
Engage with a dynamic team to oversee copy responsibilities, crafting compelling content across various mediums. Collaborate creatively to drive engagement for diverse audiences, including healthcare...
1 week ago
Fast Track to Sales Manager - Insurance
$90K - $110K *
Take ownership of driving sales success while mentoring and training new agents. You'll master our sales system and lead a team to achieve high performance, ensuring both personal sales and team growt...
1 week ago
$75K - $100K *
Champion growth by engaging clients and driving sales in life insurance. Take ownership of your career with unlimited income potential and comprehensive training. Join a dynamic team focused on result...
1 week ago
$110K - $130K *
Empower your career by joining a dynamic team as a Field Support Engineer, where you'll tackle complex technical challenges in mission-critical environments, leveraging your expertise in Red Hat OpenS...
1 week ago
$95K - $115K *
Elevate your career by contributing to critical security initiatives, leveraging your expertise in incident response, cryptographic modernization, and technical policy formulation to enhance enterpris...
1 week ago
Regional Vice President of Sales (Lower Midwest)
$175K *
Engage with high-net-worth clients, converting prospects to loyal partners. Leverage provided leads and support to educate about wealth management solutions while developing your sales expertise in a...
Reposted 1 week ago
$83K - $104K *
Join a team that's driving strategic marketing initiatives and influencing success. Collaborate with leaders to develop compelling narratives and innovative strategies that elevate project pursuits an...
1 week ago
$100K - $110K *
Drive valuable insights by enhancing Anaplan models and dashboards, collaborating with teams to implement solutions and improve functionality, while supporting users throughout the development lifecyc...
Reposted 1 week ago
Field Sales Executive, Cloud Software Solution Sales *Remote*
$71K - $124K *
Champion sales growth by managing CPA firm accounts, implementing strategies, and driving product engagement. Collaborate with teams to enhance client relationships and contribute to product developme...
1 week ago
Senior Mechanical Commissioning Engineer/Specialist
$120K - $160K *
Join a team to lead commissioning projects, providing technical expertise and project management for critical facilities. Collaborate across teams, mentor others, and ensure successful testing and val...
Reposted 1 week ago
Regional Sales Director - Federal
$385K - $400K *
Transform regional sales performance by leading a high-impact team, driving strategic growth, and utilizing best practices to meet ambitious quotas within a dynamic environment. Foster relationships a...
Reposted 1 week ago
Regional Director - Hematology - Ohio Valley
$212K - $287K *
Transform the Hematology landscape by leading a high-performing sales team, driving strategic initiatives, and ensuring compliance while exceeding sales objectives in the Great Plains region...
1 week ago
Senior Solutions Architect, Telco
$184K - $356K *
Drive technical engagement with telecom accounts, connecting customer workloads to NVIDIA's ecosystem. Serve as a trusted advisor, co-design scalable architectures, and lead technical enablement to en...
1 week ago
$145K - $170K *
Join us to drive strategic sales initiatives, leveraging a robust resource model and tech stack to achieve performance goals and maximize customer value in a dynamic, collaborative environment...
1 week ago
Global Property Claims Adjuster
$80K - $90K *
Transform the claims landscape by managing commercial property claims, collaborating with diverse teams, and enhancing your expertise in global and excess lines. Join a dynamic environment focused on...
1 week ago
$80K - $95K *
Empower the CDL program by leading training initiatives, ensuring compliance, and optimizing fleet management. Collaborate with regional leaders to enhance operational efficiency and drive revenue gro...
1 week ago
CMC Program Lead TLX597 & TLX66
$135K - $160K *
Lead the charge in developing and executing CMC strategies for antibody-based radiopharmaceuticals, ensuring alignment with Stage-Gate requirements while managing cross-functional teams and external p...
1 week ago
Training Manager, Field Access & Reimbursement
$124K - $135K *
Shape impactful training programs for Field Access teams, enhancing access and reimbursement capabilities across therapeutic areas. Collaborate with stakeholders to ensure compliance and relevance, fo...
1 week ago
Staff Pharmacist - Accredo - Remote (AZ, FL, IN, OH, PA)
$112K - $189K *
Lead the charge in delivering exceptional pharmaceutical care by interpreting prescriptions, consulting with patients, and ensuring quality assurance. Collaborate with healthcare professionals to opti...
1 week ago
$80K - $95K *
Empower developers by diagnosing and resolving complex technical issues related to APIs. Collaborate across teams, advocate for improvements, and enhance developer experiences in a fast-paced, innovat...
Reposted 1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.