Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
$85K - $110K *
Lead and oversee a dynamic Biomedical team, managing projects, costs, and quality across facilities. Drive performance, compliance, and professional development while ensuring optimal staffing and ope...
1 week ago
Epic Systems Analyst - Ambulatory
$68K - $105K *
Transform your career by configuring and supporting Epic applications. Engage in systems analysis, design, and problem resolution while collaborating with end-users to enhance their experience and str...
1 week ago
Senior Regulatory Affairs Consultant - Regulatory Project Manager
$120K - $145K *
Join a team that shapes global regulatory strategy in a fast-paced environment. You will lead comprehensive regulatory plans, ensuring alignment and execution from development to post-marketing, impac...
Reposted 1 week ago
$95K - $115K *
Manage daily pharmacy operations, ensuring optimal patient care and compliance. Lead staff training, develop policies, and enhance service quality while monitoring performance and resource allocation...
1 week ago
Partner Growth Manager - West Coast
$100K - $120K *
Join a team that's focused on driving partner growth in the travel industry. Leverage your expertise to build relationships, implement strategic plans, and engage clients, all while thriving in a coll...
1 week ago
Maintenance Journeyman 1/Electrical
$84K *
Join a team that's dedicated to maintaining and optimizing electrical and instrumentation systems. This role involves hands-on troubleshooting, repair, and preventive maintenance in an industrial envi...
1 week ago
Professional Services Operations Lead
$88K - $105K *
Drive operational excellence by owning the Professional Services intake and workflow governance processes, ensuring efficient request management and seamless team collaboration to enhance service deli...
1 week ago
Talent Acquisition Partner - US
$90K - $110K *
Shape the future of talent acquisition by managing end-to-end recruitment processes, collaborating with cross-functional teams, and optimizing hiring strategies to attract top talent in a fast-paced e...
1 week ago
Account Executive - Mountain States
$100K - $120K *
Engage with government agencies to drive revenue through strategic partnerships. Cultivate relationships, identify opportunities, and execute sales strategies to meet growth objectives in the Intellig...
1 week ago
Business Development Manager - Cruise Missiles (Navy and USMC)
$131K - $237K *
Unlock potential by driving business growth in the cruise missile sector, engaging with U.S. Navy and Marine Corps stakeholders to identify and capture new opportunities while collaborating with cross...
1 week ago
Director, Intelligence Planning & Execution
$185K - $344K *
Join a dynamic team driving strategic planning and performance management across analytics capabilities. Lead portfolio governance and execution initiatives to align resources and priorities, ensuring...
1 week ago
Senior Manager/Associate Director, Funding the Next Generation (FNG)
$90K - $113K *
Lead strategic initiatives to enhance advocacy for California's children and youth. Collaborate with stakeholders, manage programs, and drive fundraising efforts to ensure impactful policy changes and...
1 week ago
$90K - $110K *
Drive end-to-end payroll processes across multiple entities, ensuring accuracy and compliance. Manage domestic and international payroll, tax setups, and employee inquiries while building scalable sys...
1 week ago
Proposal Manager, Radar & Surveillance
$81K - $136K *
Join a team that's pioneering innovative radar and surveillance solutions. Lead proposal management and program execution, ensuring high-quality submissions while collaborating across functions to dri...
1 week ago
Engineering Manager, Tenant Scale: Gitaly
$150K - $180K *
Lead the charge in managing a technical team focused on Gitaly, driving performance, scalability, and maintainability while fostering a culture of accountability and ownership across distributed teams...
1 week ago
Salesforce Senior/ Director Technical Architect, FINS/LSC
$148K - $313K *
Unlock potential by serving as a strategic advisor to enterprise clients, guiding them in architecting AI-first solutions within the Life Sciences sector, while driving internal initiatives and enhanc...
Reposted 1 week ago
$110K - $130K *
Join a team that's redefining application security by guiding customers through complex evaluations. Leverage your expertise in offensive security to build relationships, deliver impactful demos, and...
1 week ago
Account executive-North Central US
$110K - $130K *
Drive growth by building and expanding enterprise pipelines through strategic outbound efforts and executive networking. Collaborate cross-functionally to secure high-value deals and establish long-te...
1 week ago
$90K - $110K *
Lead the charge in providing comprehensive psychiatric care to individuals and families. Utilize your expertise to assess, diagnose, and treat mental health conditions while collaborating with medical...
1 week ago
$125K - $150K *
Unlock potential by architecting innovative IT solutions that align with client goals. Collaborate with sales teams and engage directly with customers to deliver tailored strategies, ensuring successf...
1 week ago
Environmental Chemist/Data Validator
$73K - $132K *
Join a dynamic team as a Senior Environmental Chemist, providing expert oversight in environmental data management and validation. Lead projects ensuring compliance and quality in remediation efforts...
Reposted 1 week ago
Technical Sales Lead - USA GOV
$144K - $230K *
Engage with our sales team as a Technical Sales Lead, driving technology evaluations and managing customer relationships. Leverage your expertise in telecommunications to ensure satisfaction throughou...
1 week ago
Clinical Documentation Integrity Supervisor
$110K - $159K *
Empower the Clinical Documentation Integrity team by ensuring staff competency through quality assurance, training, and performance management. Collaborate on action plans and foster associate develop...
1 week ago
ED, Advance Analytics and Precision Health
$225K - $418K *
Champion advanced analytics to enhance patient outcomes through data-driven insights. Lead a team in analyzing healthcare data, fostering strategic partnerships, and communicating complex findings to...
1 week ago
Associate Director, Analytics Governance & Operations
$152K - $283K *
Accelerate analytics governance and operations by leading initiatives that enhance decision-making processes, streamline reporting, and modernize workflows across teams, ensuring effective collaborati...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.