Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
$100K - $130K *
Transform healthcare by leading a dynamic PMO, ensuring program transparency and compliance across multiple customer accounts while fostering collaboration and continuous improvement...
1 week ago
$75K - $90K *
Unlock new business opportunities by developing strategic marketing and sales plans. Collaborate with executives to secure and grow employer accounts, driving revenue growth and expanding market share...
1 week ago
Market Development Director (Health Systems - Southeast)
$125K - $150K *
Join a team that's transforming healthcare by driving enterprise sales and partnerships with leading health systems. Leverage your expertise to educate executives on innovative solutions that enhance...
1 week ago
Key Account Manager (US) (m/f/d)
$80K - $100K *
Develop strategic customer relationships and expand international presence by acquiring new enterprise clients and nurturing existing accounts in the pharmaceutical and life sciences sectors...
1 week ago
Sr. Marketing Operations Technologist
$88K - $120K *
Explore innovative marketing automation solutions by collaborating with teams to implement Salesforce Marketing Cloud technologies, ensuring high-quality execution and strategic alignment for client c...
1 week ago
$165K - $185K *
Unlock your potential by leading the design and implementation of innovative digital solutions for Veteran healthcare services. Collaborate with cross-functional teams to enhance enterprise applicatio...
1 week ago
$166K - $200K *
Engage with strategic accounts to drive sales growth and build influential relationships. Leverage deep industry knowledge to create tailored solutions, manage complex negotiations, and achieve perfor...
1 week ago
Clinical Project Research Manager - EDS/RWE/NIS
$100K - $120K *
Elevate project outcomes by leading cross-functional teams to deliver clinical research projects on time and within budget, ensuring compliance with regulatory standards and client expectations while...
Reposted 1 week ago
Solutions Support Engineer - US East
$126K - $172K *
Transform customer experiences by providing expert technical support, troubleshooting issues, and implementing scalable solutions. Collaborate with global teams to enhance service delivery and ensure...
1 week ago
$160K - $190K *
Shape the future of our legal operations by leading in-house legal efforts, managing contracts, advising on compliance, and collaborating with leadership to drive strategic initiatives across commerci...
1 week ago
Senior Product Manager, AI Evaluation & Quality| Level 18| US: Remote
$150K - $159K *
Analyze and build evaluation frameworks for AI agents, ensuring quality and performance meet client and business standards. Collaborate with cross-functional teams to establish testing methodologies a...
1 week ago
$75K - $90K *
Unlock potential by exploring various technology disciplines at the Designer I level. Collaborate with mentors, gain hands-on experience, and apply fundamental skills across ICT, Security, AV, and mor...
Reposted 1 week ago
$69K - $101K *
Grow your career with a dynamic team providing holistic clinical care management services. Collaborate with diverse populations to enhance health outcomes through assessment, care planning, and coordi...
1 week ago
Senior Production Underwriting Specialist - Excess/Umbrella
$126K - $170K *
Elevate your career by driving risk selection and profitability in a dynamic Excess Liability Division. Collaborate with clients and internal teams to deliver tailored insurance solutions while mainta...
1 week ago
Senior Product Manager - Inference Platform
$228K - $285K *
Pioneer advancements in AI inference platforms, driving strategy and execution across cross-functional teams to enhance scalability and reliability for enterprise customers. Lead product initiatives f...
1 week ago
$144K - $200K *
Shape the future of enterprise technology by leading transformative consulting engagements. Collaborate with C-level executives to drive strategic initiatives in AI, cloud, and analytics, ensuring imp...
1 week ago
$80K - $95K *
Drive growth by acquiring new customers for our innovative SaaS solutions. Leverage your sales expertise to engage decision-makers, understand their needs, and promote our Amplify Platform, focusing o...
1 week ago
Account Executive, Midwest ECM
$80K - $95K *
Unlock potential by driving growth in our Enterprise Content Management business. Engage with diverse stakeholders, navigate complex sales cycles, and expand client relationships across the Midwest wh...
1 week ago
$115K - $130K *
Drive financial success by overseeing BIM project operations, managing budgets, and collaborating with stakeholders to ensure alignment with organizational objectives while delivering comprehensive fi...
1 week ago
Sr. Sales Account Executive - West
$135K - $245K *
Unlock your potential as a Senior Sales Account Executive, driving strategic sales initiatives across diverse industries. Engage with C-level executives, manage complex sales cycles, and leverage inno...
1 week ago
Treasury Manager, Capital Markets
$110K - $130K *
Manage key capital markets activities, overseeing debt operations, cash flow forecasting, and financial risk management. Collaborate with stakeholders to prepare executive materials and support pensio...
1 week ago
Manager, Digital Marketing Operations
$86K - $110K *
Take ownership of digital marketing operations, managing CRM campaigns and creative processes. Collaborate across teams to enhance performance, streamline workflows, and leverage AI for improved resul...
1 week ago
$175K - $200K *
Transform compliance within a dynamic enterprise by designing and overseeing an effective Ethics and Compliance Program that aligns with regulations and promotes enterprise growth. Drive culture and a...
Reposted 1 week ago
$140K - $160K *
Unlock potential by driving the evolution of AWS environments and CI/CD pipelines, enhancing observability and security, while collaborating with engineers to optimize platform reliability and perform...
1 week ago
Senior Manager - Regulatory Affairs
$85K - $120K *
Lead the charge in regulatory affairs by providing strategic guidance, ensuring compliance, and fostering collaboration across institutions. Drive initiatives from research to implementation while men...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.