Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
$80K - $95K *
Grow your career with a dynamic role managing end-to-end event strategies, logistics, and sales partnerships. Drive impactful industry conferences and user events that significantly contribute to pipe...
1 week ago
$100K - $125K *
Join a team that's dedicated to delivering expert tax solutions while ensuring compliance and fostering client relationships. Leverage your extensive experience in tax preparation and planning to driv...
1 week ago
$180K - $210K *
Accelerate progress at the forefront of AI integration, designing secure enterprise architectures that enhance healthcare services for Veterans. Lead initiatives across cloud and on-premise platforms...
1 week ago
Staff Scientist, Bioinformatics/RWD
$158K - $197K *
Transform real-world health data into actionable insights by leveraging advanced bioinformatics and AI techniques. Lead innovative analyses in oncology and genomics, facilitating cross-functional coll...
Reposted 1 week ago
Senior Copywriter, Promotional Medical Writing
$80K - $100K *
Shape the future of medical communications by crafting high-quality, scientifically accurate content. Collaborate with diverse teams to deliver impactful resources that meet client needs while mentori...
1 week ago
$124K - $207K *
Transform global benefits strategies by leading a dynamic team, ensuring compliance, and enhancing employee wellbeing. Drive innovative solutions while managing vendor relationships and collaborating...
1 week ago
Director, Audience Intelligence Products| US: Remote
$150K - $159K *
Lead the charge in transforming audience intelligence through innovative product strategies, enhancing consumer insights and data-driven solutions for brands and partners while ensuring privacy and co...
1 week ago
Sr. Product Manager, Product Operations & Insights| US: Remote
$150K - $159K *
Drive product health standards by defining metrics and telemetry for all products. Collaborate with cross-functional teams to ensure consistent data definitions and empower teams with self-serve dashb...
1 week ago
$100K - $120K *
Advance payer integrations by managing complex processes and relationships. Drive outreach and research to establish direct connectivity with 3,000+ payers, ensuring accurate data and efficient handof...
1 week ago
Manager, Network Management (National Health Systems)
$54K - $159K *
Champion contract negotiations by driving initiatives, cultivating relationships, and ensuring compliance with performance goals. Leverage expertise to support cost-saving strategies and enhance cross...
Reposted 1 week ago
$120K - $160K *
Manage labor and employment legal matters, ensuring compliance and providing strategic counsel. Collaborate with HR and stakeholders to develop solutions, supervise outside counsel, and educate on pol...
1 week ago
$120K - $145K *
Drive mobile engineering excellence by leading app development, mentoring engineers, and integrating AI solutions to enhance user experiences across iOS and Android platforms while collaborating with...
1 week ago
Human Resources Business Partner (HRBP) - Carmel, IN or Remote Indiana
$80K - $95K *
Join a dynamic team as a strategic HR partner, driving organizational success through effective talent management, employee engagement, and operational support. Collaborate with leaders to align HR in...
1 week ago
Senior Enterprise Account Executive, General Manufacturing
$100K - $150K *
Accelerate progress at a dynamic SaaS company by driving revenue growth through strategic sales cycles. Leverage your expertise in complex enterprise solutions to build relationships and exceed target...
1 week ago
Nurse Practitioner-Pediatric Critical Care Unit-PICU-Full Time and Part Time
$95K - $115K *
Empower patient health by managing care in a dynamic pediatric critical care unit. Collaborate with physicians to assess, diagnose, and implement comprehensive care plans while mentoring nursing staff...
1 week ago
AVP & Actuary - Stop Loss Captives - Remote
$155K - $259K *
Shape the future of our captive and reinsurance business by leading actuarial strategies, optimizing structures, and delivering insights that drive profitable growth through collaboration and analytic...
1 week ago
Territory Growth Manager - Integrated Solutions, Motion Control
$110K - $130K *
Drive growth and expand market presence by managing territory sales, developing customer relationships, and collaborating cross-functionally to achieve strategic objectives in the Motion Control secto...
1 week ago
Senior Software Engineer, Certificates Management
$186K - $218K *
Champion the development of critical cryptographic infrastructure, leading high-availability services and innovative solutions while collaborating with cross-functional teams to ensure secure executio...
1 week ago
$110K - $130K *
Transform asset management processes by developing and enhancing Oracle EBS modules, ensuring seamless integration and automation for improved efficiency and compliance in financial operations...
1 week ago
$90K - $110K *
Join a team that's driving sales growth in the home improvement sector. This role focuses on developing dealer partnerships, expanding market presence, and achieving sales objectives through strategic...
1 week ago
Senior Accountant, Financial Reporting
$78K - $130K *
Drive financial accuracy and transparency by managing external reporting, technical accounting, and equity accounting. Collaborate with cross-functional teams to ensure compliance with U.S. GAAP and S...
1 week ago
Senior Tax Associate - UHNW (Northeast)
$99K - $110K *
Lead the preparation and delivery of tax returns for ultra-high-net-worth clients. Enjoy a supportive environment with no billable hours, focusing on client service and tax compliance while benefiting...
1 week ago
$240K - $330K *
Transform security operations by leading a dynamic Product Security team. Drive risk-based strategies, empower engineering teams, and enhance security posture through automation and collaboration. Sha...
Reposted 1 week ago
$110K - $130K *
Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...
1 week ago
Senior AI Software Engineer (RD271)
$130K - $155K *
Drive innovation by developing AI-driven software solutions that enhance secure application delivery. Collaborate with cross-functional teams to tackle complex challenges and shape the future of softw...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.