Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,580

Sort By: Relevance

$105K - $150K *

Lead product management for complex digital services, mentoring a team of Product Managers. Collaborate with stakeholders to define strategies, prioritize needs, and deliver impactful outcomes while f...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$92K - $120K *

Join a team that's dedicated to enhancing sales performance through innovative training. You'll design and deliver engaging learning experiences, collaborate with sales leaders, and leverage AI tools...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$216K - $361K *

Drive customer retention and growth by managing strategic accounts, collaborating cross-functionally to enhance customer experiences, and achieving revenue targets through effective account planning a...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Drive compliance and accuracy in financial reporting, overseeing SEC filings and governance. Collaborate with leadership to enhance transparency and support strategic initiatives while ensuring adhere...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Optimize production processes and drive innovation in biocarbon manufacturing. Collaborate with a core team to enhance safety, efficiency, and product quality while minimizing costs and energy use in...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$292K - $344K *

Champion the growth of agency sales by leading a dynamic team, driving revenue, and fostering strong client relationships. Collaborate with executives to shape strategies and ensure Fetch's value reso...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$138K - $230K *

Join a dynamic team to deliver professional services, guiding public sector clients in adopting GitLab through installations, migrations, and training. Balance technical expertise with project managem...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$83K - $113K *

Drive regional clinical study delivery by supporting management and execution of trials, ensuring quality standards and timelines are met. Collaborate with stakeholders and contribute to operational e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape client success by managing campaigns and relationships. Drive performance through strategic insights, optimize Meta advertising, and ensure client satisfaction while tackling challenges proactiv...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $100K *

Advance impactful medical communications by crafting precise, engaging content. Collaborate with cross-functional teams to ensure accuracy and alignment with client objectives while mentoring junior s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $158K *

Manage and prioritize the ERP product backlog, translating business needs into actionable requirements. Collaborate with stakeholders to enhance operational effectiveness and drive continuous improvem...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$140K - $170K *

Shape the future of healthcare market strategies by analyzing trends, defining growth initiatives, and collaborating cross-functionally to drive innovation in life science and medical services. Lead m...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Accelerate your career by driving revenue growth with enterprise clients. Leverage your sales expertise in the fashion industry to build relationships, identify needs, and deliver tailored solutions t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$170K - $220K *

Drive your career forward by leading cross-functional deployment strategies. This senior role requires exceptional judgment and communication skills to navigate complex, ambiguous situations and deliv...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$190K - $267K *

Lead data-driven strategies to enhance product development and user growth. Collaborate across teams to implement sophisticated analyses and metrics that drive business decisions and mentor junior tea...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Media

$135K - $182K *

Empower operational excellence by leading a dynamic team to enhance safety, quality, and performance. Drive continuous improvement initiatives while fostering a culture of leadership development and e...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$153K - $220K *

Shape the market presence of our innovative cybersecurity solutions through strategic messaging, product launches, and sales enablement. Collaborate with teams to drive demand and elevate the buyer's...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$93K - $140K *

Elevate cloud security by enhancing standards and implementing risk-based controls across Azure and AWS. Collaborate with teams to secure applications and support AI initiatives, ensuring robust gover...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$97K - $161K *

Drive the design and implementation of security systems, enhancing existing solutions while solving complex challenges. Collaborate with cross-functional teams to ensure robust cybersecurity measures...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Grow your career with a dynamic role managing end-to-end event strategies, logistics, and sales partnerships. Drive impactful industry conferences and user events that significantly contribute to pipe...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $125K *

Join a team that's dedicated to delivering expert tax solutions while ensuring compliance and fostering client relationships. Leverage your extensive experience in tax preparation and planning to driv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$180K - $210K *

Accelerate progress at the forefront of AI integration, designing secure enterprise architectures that enhance healthcare services for Veterans. Lead initiatives across cloud and on-premise platforms...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$158K - $197K *

Transform real-world health data into actionable insights by leveraging advanced bioinformatics and AI techniques. Lead innovative analyses in oncology and genomics, facilitating cross-functional coll...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Shape the future of medical communications by crafting high-quality, scientifically accurate content. Collaborate with diverse teams to deliver impactful resources that meet client needs while mentori...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$124K - $207K *

Transform global benefits strategies by leading a dynamic team, ensuring compliance, and enhancing employee wellbeing. Drive innovative solutions while managing vendor relationships and collaborating...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.