Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,580

Sort By: Relevance

$93K - $117K *

Join a team that's shaping data-driven decisions by building robust analytics models, collaborating with stakeholders, and ensuring data integrity. Leverage your expertise in SQL and BI tools to empow...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$190K - $200K *

Lead the charge in executing capital markets strategies for debt financings, managing end-to-end deal processes, and collaborating across teams to ensure compliance and reporting for a growing portfol...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$78K - $103K *

Champion accurate coding by interpreting diagnoses and resolving claim errors in this remote role. Leverage your expertise to ensure compliance with CPT, ICD-10, and HCPCS standards while collaboratin...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Drive the resolution of complex surety disputes by conducting technical analyses, collaborating with consultants, and advising on construction and claims management, while leading teams to assess risk...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Grow your leadership skills by managing engineering and test operations, overseeing propulsion programs, and ensuring facility safety and efficiency. Collaborate with diverse teams to drive innovation...

1 week ago

  •   8 - 10 years exp.  •   Transportation

$103K - $181K *

Unlock your potential by leading innovative rail transit projects, managing complex CBTC systems, and ensuring compliance with industry standards while fostering a culture of continuous improvement an...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$92K - $110K *

Champion the future of healthcare by delivering comprehensive, evidence-based care to patients with diverse health needs. Collaborate with interdisciplinary teams to enhance patient outcomes and lead...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Unlock potential by managing client relationships and Meta campaigns, ensuring performance and retention. Lead strategy discussions, optimize advertising efforts, and translate data into actionable in...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$59K - $130K *

Unlock your potential as a hands-on HR Business Partner, supporting a dynamic team. Engage with employees, coach leaders, and foster a positive workplace culture while managing HR operations and drivi...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$170K - $200K *

Lead the charge in managing complex Life Sciences programs, ensuring alignment with customer commitments. Drive delivery across teams, proactively addressing risks and building a PMO as the business s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Explore the complexities of Russian and Eurasian crypto threats, owning end-to-end attribution and analysis. Collaborate with a global team to produce actionable intelligence and represent expertise i...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$142K - $192K *

Drive the growth of an insurance tax team by managing client relationships, guiding professionals, and leveraging your expertise to enhance compliance strategies and revenue generation. Stay ahead of...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Elevate your career by leading the design and delivery of secure, reliable applications and cloud services. Collaborate with engineers, enhance operational excellence, and drive continuous improvement...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$97K - $151K *

Unlock your potential as you drive agency growth and enhance profitability through strategic relationship management and innovative sales practices in the Midwest territory. Lead initiatives that empo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$166K - $230K *

Innovate the borrower experience by leading complex software projects, shaping architecture, and mentoring engineers. Collaborate across teams to deliver high-quality, scalable solutions that enhance...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Drive integrated marketing strategies that enhance brand visibility and demand generation across diverse industries. Collaborate with sales and stakeholders to execute impactful campaigns and events...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Join a dynamic team to design and develop innovative software applications, enhancing internal processes and client interactions. Leverage your technical expertise in Salesforce, SQL, and Agile method...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$145K - $175K *

Transform healthcare technology by leading digital innovation, data management, and AI initiatives. Collaborate across teams to enhance patient experience and operational performance while driving the...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$153K - $220K *

Transform demand generation strategies into actionable plans that drive revenue growth. Collaborate with marketing leaders to optimize the lead lifecycle and enhance funnel performance, ensuring align...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$185K - $235K *

Transform engineering practices by leading AI Enablement initiatives, enhancing workflows, and driving adoption of AI standards across teams. Collaborate with stakeholders to measure progress and deli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$255K - $383K *

Transform enterprise relationships by leading strategic sales initiatives, managing complex cycles, and nurturing partnerships to drive significant revenue growth in a high-impact territory...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $110K *

Transform financial operations by providing analytical support, enhancing reporting processes, and collaborating with cross-functional teams to drive profitability and efficiency in budgeting and fore...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Accelerate progress at customer success by managing a diverse portfolio, ensuring product adoption, and driving retention through proactive engagement and collaboration with cross-functional teams...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $155K *

Unlock potential by rapidly transforming customer insights into innovative prototypes. Collaborate with a dynamic team to build scalable products from scratch, leveraging AI tools and existing platfor...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$284K - $385K *

Shape the future of technology by tackling complex challenges and driving AI adoption. Collaborate across teams to define long-term strategies, enhance customer experiences, and influence product dire...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.