Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,063

Sort By: Relevance

$156K - $220K *

Unlock your potential by leading the paid media strategy in a transformative role involving creative innovation and team development, driving growth through data-driven decisions across multiple chann...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Media

$65K - $116K *

Drive exceptional client experiences by leading delivery operations, managing relationships, and leveraging analytics to identify service gaps. Collaborate cross-functionally to ensure seamless execut...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$86K - $106K *

Drive advertiser growth by optimizing campaign performance and building strong client relationships. Collaborate with internal teams to enhance product offerings and ensure a seamless advertiser exper...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Consumer Technology

$180K - $220K *

Shape the future of healthcare delivery by leading operations in denials resolution and payment compliance. Drive performance, quality, and financial outcomes while building a high-performing team and...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$159K - $168K *

Discover impactful opportunities by leading state and local government affairs in the Midwest, advocating for public policies that enhance community engagement and support the growth of a leading e-co...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

$210K - $250K *

Join a team that's driving strategic growth and profitability in healthcare solutions. Lead cross-functional initiatives, own P&L, and ensure client success while shaping market strategy and solution...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Healthcare

$91K - $118K *

Accelerate your career by driving technical solutions and proposals for engineered equipment. Collaborate with sales and engineering teams to ensure customer satisfaction and secure new business oppor...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Transform the Industrial Segment by leading growth strategies across the Americas. Drive sales accountability, foster key relationships, and collaborate cross-functionally to enhance customer satisfac...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$134K - $170K *

Elevate partner success by managing key retail relationships, driving insights, and executing growth strategies. Collaborate cross-functionally to implement operational innovations and support the evo...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

$193K - $309K *

Join a dynamic team to enhance cloud security capabilities, leading hands-on initiatives and shaping strategic direction. Collaborate across engineering teams to secure AWS environments and mentor pee...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Join a team that's transforming legacy systems into modern applications using Java and cloud technologies. Collaborate in an Agile environment to enhance performance, security, and reliability while e...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$193K - $309K *

Empower the development of innovative features on a high-traffic Orders platform, collaborating across teams to enhance architecture and tooling, ensuring efficient processing for over 1 billion order...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$75K - $90K *

Join a team that's transforming supply chain planning through data-driven insights and cross-functional collaboration. Your expertise will enhance demand forecasting, inventory management, and strateg...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$75K - $93K *

Join us to develop and deliver impactful training programs that enhance customer engagement and retention. Collaborate with leaders to identify performance gaps and create solutions that drive measura...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Lead data-driven strategies to enhance revenue growth across customer acquisition, retention, and expansion. Collaborate with cross-functional teams to establish integrated metrics and actionable insi...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$225K - $265K *

Shape the future of oncology by leading clinical studies in early-phase development. Collaborate with multidisciplinary teams to drive innovative therapies and ensure high-quality execution of clinica...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in optimizing fleet maintenance operations through strategic planning, data governance, and innovative automation. Drive results by enhancing system integration and building strong par...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$137K - $221K *

Empower innovation by designing and implementing core platform services for agent execution. Collaborate with cross-functional teams to build reliable APIs and workflows, ensuring robust performance a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$210K - $250K *

Lead the transformation of data and AI into business value, driving strategy, governance, and adoption across the organization. Collaborate with stakeholders to enhance analytics maturity and build a...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Finance & Insurance

$100K - $120K *

Transform payment strategies by analyzing interchange and routing data to optimize costs and enhance performance. Leverage advanced analytics and automation to deliver actionable insights for stakehol...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$79K - $116K *

Optimize project delivery by supporting large-scale warehouse automation deployments. Engage with cross-functional teams to track deliverables, manage risks, and maintain schedules, ensuring successfu...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Empower facility operations by providing expert maintenance support across multiple centers. Lead training, audits, and contractor management to ensure compliance and enhance operational efficiency in...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$124K - $186K *

Champion the design and integration of advanced instrumentation and control systems, ensuring safe and reliable operations at a dynamic test facility. Collaborate with cross-functional teams to drive...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$145K - $169K *

Transform the South Zone's beverage landscape by driving strategic growth, aligning stakeholders, and executing innovative plans that enhance market performance and profitability across a diverse Coca...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$232K - $320K *

Unlock potential by leading a dynamic Solutions Consulting team to deliver innovative cybersecurity solutions. Collaborate with sales and customers to ensure value realization and drive success in pre...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.