Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
$160K - $170K *
Elevate data engineering excellence by designing and implementing complex data solutions, mentoring engineers, and collaborating across teams to drive impactful data initiatives and architectural inno...
Reposted 1 week ago
$80K - $95K *
Advance compliance operations by conducting transaction monitoring, investigating suspicious activities, and collaborating cross-functionally to ensure regulatory adherence in a dynamic digital asset...
1 week ago
$160K - $200K *
Lead the charge in defining GTM Engineering at Omnissa, shaping the vision, roadmap, and systems to enhance efficiency across Sales, Marketing, and Customer Success. Drive innovation and ownership in...
1 week ago
Senior Forward Deployed Engineer (Full-Stack)
$250K - $400K *
Shape the future of AI by partnering with customers to design and deliver innovative data solutions. Collaborate with a senior team to tackle complex challenges and transform vague requests into actio...
1 week ago
$120K - $145K *
Unlock potential by driving commercial growth strategies for a product family. Collaborate across teams to translate market insights into actionable plans that enhance revenue, profitability, and cust...
1 week ago
Senior Director, Early Oncology
$230K - $345K *
Transform clinical trial management by leading early-phase oncology programs. Drive strategic vision, operational excellence, and cross-functional collaboration to ensure timely, budget-compliant exec...
1 week ago
$80K - $100K *
Unlock your potential by contributing to enterprise EDI and integration projects. Collaborate with experienced engineers to design, implement, and optimize solutions, enhancing customer satisfaction a...
1 week ago
Professional Infrastructure Operations Network Specialist
$83K - $103K *
Elevate your career by providing critical network support across multiple sites, ensuring seamless infrastructure operations and collaboration with global teams to enhance business solutions and user...
1 week ago
Strategic Account Executive, Named Accounts (Remote, US)
$110K - $130K *
Drive your career forward by managing strategic enterprise accounts, fostering relationships, and identifying growth opportunities. Leverage your sales expertise to navigate complex cycles and collabo...
1 week ago
$130K - $155K *
Join a dynamic team to architect and deliver a cloud-native maintenance planning tool, driving modernization efforts and collaborating with diverse stakeholders to ensure seamless project execution an...
1 week ago
$110K - $130K *
Lead cross-functional project execution in Medication Contracting, translating strategic priorities into actionable plans. Drive improvements, manage risks, and enhance collaboration across teams to e...
1 week ago
$180K - $200K *
Join a dynamic team to drive AI solutions in wealth management. Collaborate with executives to design tailored solutions, ensuring seamless integration and customer satisfaction while fostering innova...
1 week ago
Senior Strategic Program Manager
$90K - $108K *
Champion high-impact strategic initiatives, collaborating with executives to drive alignment and measurable results across the organization while navigating complexity and change...
1 week ago
Senior Dynamics Systems Analyst
$100K - $120K *
Join a dynamic team to lead a global transition to D365 F&O, enhancing finance operations through process improvements and automation. Collaborate across departments to streamline complex business pro...
Reposted 1 week ago
$160K - $225K *
Join us to build and lead our accounting function from the ground up, overseeing outsourced operations, establishing internal controls, and preparing for our first audit while driving system implement...
1 week ago
Medical Science Liaison, CNS - AR, LA, OK
$150K - $224K *
Advance patient outcomes by leveraging your expertise in CNS as a Medical Science Liaison. Collaborate with healthcare providers and stakeholders to deliver evidence-based insights and drive strategic...
1 week ago
$90K - $110K *
Lead the charge in delivering innovative managed services solutions by partnering with sales teams to assess client needs, design scalable architectures, and ensure seamless transitions, driving long...
1 week ago
Bilingual Hybrid Development Representative - Mandarin
$75K - $120K *
Optimize customer connections by driving high-volume outreach and qualifying leads as a Bilingual Hybrid Development Representative. This role serves as a launchpad for aspiring Account Executives, fo...
Reposted 1 week ago
Senior Partner Marketing Manager, Nationals
$145K - $185K *
Join a team that's redefining partner marketing strategy, driving pipeline growth, and fostering relationships with national partners. Leverage your expertise to execute impactful campaigns and collab...
1 week ago
Director, User Experience Design
$148K - $245K *
Transform user experience across global retail and e-commerce platforms by leading a multidisciplinary team, driving design excellence, and integrating AI into innovative solutions that enhance custom...
1 week ago
Commercial Solution Sales Executive, Cybersecurity
$110K - $140K *
Accelerate progress at driving sales execution and client relationships across commercial accounts. Lead solution-specific cycles, collaborate with experts, and achieve growth objectives while deliver...
1 week ago
$110K - $130K *
Join a team that's dedicated to enhancing client delivery and operational efficiency. As a Program Manager, you'll lead complex projects, manage cross-functional teams, and drive successful software i...
1 week ago
$130K - $150K *
Help us transform care delivery by advising providers on outcomes-based models, implementing frameworks, and leveraging data insights to enhance clinical practices and payer relationships in a collabo...
1 week ago
$125K - $150K *
Unlock potential by leading Health and VA claims operations, driving strategic initiatives, enhancing recovery outcomes, and ensuring operational excellence across multiple teams and client portfolios...
1 week ago
Sourcing Specialist (EPC/Utilities)
$80K - $95K *
Join us to drive strategic sourcing for T&D EPC projects, transforming challenges into opportunities. Collaborate with teams to secure essential materials and build supplier partnerships that power in...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.