Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,063

Sort By: Relevance

$193K - $309K *

Lead the development of innovative drive-thru solutions, architecting scalable Android applications and backend integrations while mentoring engineers and driving engineering excellence across the org...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $193K *

Accelerate progress at the intersection of security and technology by leading integration product management for enterprise security capabilities across multiple business units, ensuring streamlined a...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$73K - $102K *

Shape the future of technology by leading automation efforts, enhancing software quality, and collaborating across teams to deliver innovative solutions. Drive the development and implementation of ro...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$150K - $200K *

Lead the charge in optimizing clinical documentation processes, enhancing provider education, and fostering collaboration with service line leaders to improve documentation integrity and reduce admini...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$157K - $196K *

Drive safety evaluation and risk management for assigned programs, collaborating with cross-functional teams to ensure compliance and effective governance in pharmacovigilance activities, while suppor...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $165K *

Advance your career by leading Yardi software implementations for public housing clients. Collaborate with stakeholders to optimize workflows, enhance system configurations, and drive operational exce...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$125K - $165K *

Join a team that's dedicated to enhancing public housing through Yardi software implementation. Leverage your expertise to optimize client workflows, troubleshoot issues, and drive value in affordable...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$125K - $165K *

Elevate public housing solutions by leading Yardi software implementations, optimizing workflows, and enhancing client relationships. Drive operational excellence through expert guidance in affordable...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Shape the future of finance by leading a dynamic team in delivering exceptional outsourced accounting solutions, driving business development, and mentoring talent while ensuring client satisfaction a...

Today

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Champion the development of a robust outsourced finance practice, delivering exceptional client service while mentoring team members and managing financial performance across diverse client portfolios...

Today

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Lead the charge in building a robust outsourced finance and accounting practice, delivering exceptional client service, mentoring team members, and driving business development while managing financia...

Today

  •   8 - 10 years exp.  •   Legal & Accounting

$100K - $120K *

Elevate your career by leading a dynamic team in outsourced finance and accounting. Drive client success through exceptional service, innovative solutions, and strategic business development while men...

Today

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Reimagine client finance solutions by leading a dynamic team, enhancing service delivery, and driving business growth through innovative strategies and technology integration. Foster relationships and...

Today

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $95K *

Contribute to dental practice success by delivering impactful, in-person training on digital workflows and intraoral scanning. Collaborate with clinicians and staff to enhance clinical performance and...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$125K - $225K *

Join a team that's driving innovation in AI by developing scalable backend systems in Go, Python, and Java. Tackle complex challenges while enhancing distributed architectures to empower high-performa...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$120K - $151K *

Shape the product roadmap and drive delivery from discovery to launch, collaborating with cross-functional teams to ensure customer-centric solutions and measurable business outcomes in a dynamic B2B...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$71K - $113K *

Contribute to project success by managing cost and schedule for plant outages. Collaborate with project teams to analyze budgets, track progress, and ensure timely reporting, all while adhering to pro...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$93K - $104K *

Join a nationwide team as a Physical Therapist Assistant, delivering essential rehab services across various settings while enhancing patient independence under expert supervision. Enjoy the flexibili...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$85K - $135K *

Collaborate to drive technical issue resolution and enhance support systems while serving enterprise clients across our AI platform, ensuring seamless communication and operational excellence in a fas...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$144K - $211K *

Lead the charge in managing complex Industrial Controls workstreams, ensuring seamless execution of NPI programs. Collaborate across teams to deliver innovative automation solutions on time and within...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Transform complex systems through expert programming in Natural and ADABAS. Lead large-scale projects on IBM Mainframe/Linux, enhancing automated eligibility systems while providing strategic recommen...

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$142K - $235K *

Deliver strategic leadership in driving sales growth across non-commercial channels. Manage a team to implement innovative strategies, enhance customer partnerships, and achieve financial goals while...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$116K - $194K *

Elevate your career by joining a dynamic engineering team focused on ATM and TCR technologies. As a key technical specialist, you'll enhance customer-facing banking services through innovative solutio...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $167K *

Join a team that's driving impactful earned media strategies in a dynamic, fast-paced environment. Lead media relations, secure placements, and maintain brand consistency while leveraging AI tools for...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$224K - $431K *

Join a team that's redefining AI networking by driving innovation in performance and scalability of distributed systems, optimizing data processing for large language models and generative AI workload...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.