Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
Director, Strategic Partnerships
$200K - $260K *
Lead strategic partnerships to elevate and scale multi-year AI and LLM relationships. Collaborate cross-functionally to deepen alliances, drive integration optimizations, and advance collaborative opp...
Reposted 5 days ago
Sr Client Manager, Commercial Risk [Financial Institutions] - Innovation Practice
$95K - $115K *
Shape the future of client management by leading service teams on large accounts, enhancing carrier relationships, and developing strategic placement and renewal plans to drive success and improve pro...
5 days ago
Senior Field Marketing Manager - Public Sector, Federal & Defense
$124K - $165K *
Innovate the Federal and Defense marketing strategy by executing integrated, multi-channel programs that drive pipeline growth. Collaborate closely with sales leadership to engage diverse federal audi...
5 days ago
Senior Director, Entertainment & Sports
$135K - $180K *
Lead strategic partnerships in healthcare, connecting brands with entertainment and sports. Collaborate with teams to develop, negotiate, and execute impactful initiatives that drive brand engagement...
5 days ago
Senior Information System Security Engineer
$117K - $195K *
Advance your career as a Senior Information System Security Engineer, collaborating on critical national security projects. Drive cybersecurity initiatives, develop policies, and enhance cloud securit...
5 days ago
Senior Director, Research and Analysis
$170K - $210K *
Champion strategic growth by translating executive priorities into actionable plans. Collaborate across functions to drive performance, assess market opportunities, and ensure alignment on corporate o...
5 days ago
$121K - $182K *
Partner with us to lead complex cloud migrations, ensuring technical readiness and seamless execution across Azure and AWS environments while driving innovative solutions and high-quality outcomes in...
5 days ago
$154K - $232K *
Transform enterprise cloud strategies by leading large-scale migrations to Azure and AWS. Collaborate with global teams to establish architecture standards, ensure security, and drive innovative solut...
5 days ago
Senior Application Migration Business Analyst
$140K - $211K *
Lead the charge in transforming enterprise applications through cloud migration. Drive global initiatives, mentor teams, and solve complex challenges while ensuring seamless transitions to Azure and A...
5 days ago
Corporate Project Manager, Quality and Professional Governance
$88K - $105K *
Join a dynamic team to ensure compliance with healthcare quality standards, manage credentialing databases, and support operational objectives. Collaborate across departments to enhance quality govern...
5 days ago
Enterprise Account Executive, Michigan
$300K - $350K *
Empower your career by driving sales growth in the cybersecurity sector. Build strong customer relationships, acquire new accounts, and exceed sales quotas while managing Channel Partner relationships...
5 days ago
Enterprise Account Executive, Tennessee
$300K - $350K *
Accelerate progress at driving sales growth in the cybersecurity sector by acquiring new accounts, building relationships, and ensuring customer satisfaction. Leverage your expertise to exceed quotas...
5 days ago
Global Marketing Director, Oncology
$195K - $265K *
Transform global marketing strategies in oncology by leading cross-functional teams, driving insights, and optimizing brand value for pipeline assets. Collaborate with stakeholders to enhance commerci...
5 days ago
Manager, BD Electronic Warfare
$110K - $130K *
Unlock potential by driving business development in Electronic Warfare, managing relationships with US DoD customers, and expanding market presence through strategic sales initiatives and customer eng...
5 days ago
Mitigation and Response - Technical
$106K - $214K *
Join a team that's dedicated to enhancing cybersecurity through proactive incident response, threat analysis, and collaboration across various DHS components, ensuring the safety and integrity of nati...
5 days ago
Director, Southeast State Management
$150K - $180K *
Lead the charge in shaping pricing strategy for a key region, overseeing a talented team to drive profitable growth while navigating complex regulatory environments and leveraging data for strategic d...
Reposted 5 days ago
VP, Business Development and Earned Revenue
$172K - $211K *
Drive the development of innovative earned-revenue strategies that enhance mission impact and financial sustainability. Collaborate with cross-functional teams to identify, test, and scale viable busi...
5 days ago
Senior Project Manager, eDiscovery Staffing
$110K - $130K *
Join a team that's dedicated to delivering innovative eDiscovery solutions. Collaborate with cross-functional teams to manage client relationships, oversee project execution, and provide expert guidan...
5 days ago
$80K - $95K *
Champion operational excellence by overseeing regional profitability, managing staffing efficiencies, and driving performance improvements. Collaborate with management to achieve financial goals and e...
5 days ago
Director of Nursing Services Exempt
$80K - $95K *
Transform healthcare by leading nursing teams, managing budgets, and enhancing resident care. Collaborate with stakeholders to implement best practices and foster professional growth in a supportive e...
5 days ago
Director-Business Operations - Student Union
$80K - $95K *
Join a dynamic team to oversee business operations, financial planning, and resource management. Lead and coordinate departmental activities while ensuring compliance and enhancing productivity throug...
5 days ago
$110K - $124K *
Transform the future of AI education by mentoring fellows through their journey, guiding them in technical and organizational challenges while fostering their professional growth across diverse host o...
5 days ago
$130K - $145K *
Champion data privacy across jurisdictions by providing expert advice, managing compliance, and supporting initiatives within a global team. Collaborate with colleagues to ensure lawful handling of pe...
5 days ago
Senior Technical Program Manager
$125K - $150K *
Transform complex customer implementations into seamless successes by owning the delivery lifecycle, driving technical discussions, and ensuring stakeholder satisfaction from kickoff to go-live. Your...
5 days ago
Client Success Manager III - Energy Efficiency
$105K - $120K *
Drive client success by managing utility and energy efficiency programs, ensuring satisfaction, fostering relationships, and identifying growth opportunities while delivering on contractual obligation...
Reposted 5 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.