Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
Associate Manager AGI Research
$105K - $124K *
Lead and optimize research intern activities, ensuring alignment with project goals and technical standards. Manage workflows, provide coaching, and conduct hands-on research while supporting the Dire...
4 days ago
Senior Program Manager, Maternal Health
$100K - $120K *
Unlock potential by leading innovative strategies for AI-enabled maternal care. Drive program implementation, manage complex projects, and engage stakeholders to enhance health outcomes in low- and mi...
4 days ago
Director, Organizational Development (Southwest)
$125K *
Join a team that's redefining nonprofit leadership. Leverage your expertise to empower organizations, enhance governance, and drive sustainable growth across diverse communities while navigating compl...
Reposted 4 days ago
$110K - $130K *
Transform your career by leading a dynamic sourcing team, driving strategic initiatives, and shaping sourcing solutions for critical energy infrastructure projects. Your expertise will influence decis...
4 days ago
Principal Solutions Engineer, Strategic (East & Central)
$193K - $252K *
Join a team that's passionate about solving complex business challenges. As a Principal Solutions Engineer, you'll engage with enterprise clients, drive strategic relationships, and showcase the value...
4 days ago
$101K - $125K *
Drive the execution of immersive projects by providing technical oversight and support, ensuring seamless integration and coordination with partners globally while maintaining high standards of qualit...
4 days ago
$80K - $95K *
Accelerate progress at the forefront of cybersecurity by analyzing threats, developing countermeasures, and collaborating with teams to protect critical information systems from malicious activities a...
4 days ago
$85K - $95K *
Engage in the development and execution of automated testing strategies, ensuring software quality through comprehensive test plans and scripts. Collaborate with teams to maintain CI/CD pipelines and...
4 days ago
$115K - $125K *
Elevate your career by leading engineering teams in a dynamic environment, driving modernization and integration efforts while ensuring compliance with federal DevSecOps frameworks and delivering inno...
4 days ago
DevSecOps Engineer / Security Specialist
$95K - $125K *
Join a dynamic team to enhance security in CI/CD pipelines, integrating advanced scanning tools and hardening infrastructure across cloud platforms. Drive vulnerability management and ensure complianc...
4 days ago
$95K - $105K *
Join a dynamic team to provision and manage cloud environments, automate deployments, and ensure robust cloud security. Leverage your expertise in AWS or Azure and OpenShift to drive cloud migrations...
4 days ago
$95K - $115K *
Redefine pharmaceutical care by providing tailored drug management and clinical services. Collaborate with healthcare teams to enhance patient safety, participate in goal-oriented initiatives, and ens...
Reposted 4 days ago
$160K - $190K *
Join a team that's dedicated to delivering exceptional anesthesia care. Provide critical support during surgical and diagnostic procedures while enhancing patient safety and comfort through your exper...
Reposted 4 days ago
Manager of Utilization Management
$108K - $147K *
Lead a dynamic team in enhancing member-centered care through effective utilization management. Drive quality improvement, ensure compliance, and foster strategic partnerships to optimize healthcare d...
4 days ago
Strategic Sourcing Manager - Marketing (Content Production & Media)
$98K - $132K *
Deliver strategic sourcing solutions for Marketing Services, focusing on Content Production and Media. Collaborate cross-functionally to optimize supplier performance, drive innovation, and ensure com...
4 days ago
Global Category Lead, Full-Service CRO - Associate Director, Global Procurement R&D
$147K - $200K *
Drive strategic category management initiatives for Full-Service CRO, collaborating across teams to optimize procurement processes, reduce costs, and enhance supplier performance while ensuring compli...
4 days ago
Senior Program Manager, Contingent Workforce
$107K - $180K *
Drive the strategy and operations of a dynamic contingent workforce program, enhancing governance and service delivery. Collaborate cross-functionally to implement scalable processes and support inter...
4 days ago
Channel Systems (Sales) Engineer
$225K - $280K *
Engage as a key technical resource for channel sales, driving success with global partners. Leverage your expertise in networking solutions to enhance relationships, deliver impactful demos, and suppo...
4 days ago
Spotfire Sales Executive - Energy
$110K - $130K *
Drive growth by managing end-to-end sales cycles in the Energy sector, enhancing customer relationships, and executing strategies to exceed targets while collaborating with cross-functional teams for...
4 days ago
$68K - $105K *
Help us lead enterprise-wide incident responses and internal investigations into misconduct, ensuring compliance and effective fraud detection while collaborating across departments to uphold organiza...
Reposted 4 days ago
Lead Technical Implementation Analyst
$120K - $150K *
Transform the delivery landscape by leading cross-functional initiatives, mentoring analysts, and driving strategic solutions across business units and external partners. Engage deeply in project exec...
4 days ago
$83K - $104K *
Lead the charge in managing complex client programs, driving operational excellence and strategic direction while fostering strong stakeholder relationships and ensuring exceptional service delivery...
4 days ago
Staff Software Engineer, AI Systems
$188K - $265K *
Accelerate progress at the forefront of AI infrastructure by leading technical direction, ensuring platform architecture meets company ambitions, and fostering collaboration across engineering teams f...
Reposted 4 days ago
VP, Product Marketing - Identity Security Portfolio
$180K - $220K *
Lead the charge in transforming identity security marketing strategies, driving growth and market leadership. Oversee a dynamic team to enhance product positioning, execute go-to-market plans, and sha...
4 days ago
Project Safety Manager - Data Center
$95K - $125K *
Transform safety culture by leading project teams in compliance and incident prevention. Develop safety plans, conduct audits, and facilitate training to ensure a safe work environment on large constr...
4 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.