Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
$183K - $301K *
Accelerate growth by leading strategic partnerships and go-to-market initiatives in the healthcare ecosystem. Drive revenue through collaboration, executive influence, and innovative business models w...
5 days ago
Manager, Palliative Care (IKC)
$78K - $119K *
Lead the charge in enhancing palliative care operations, ensuring high-quality support for patients with advanced chronic illnesses. Collaborate with diverse teams to improve care coordination and pat...
5 days ago
Manager, Project Management (IC)
$54K - $159K *
Pioneer the implementation of customer benefit plans for self-funded clients, ensuring alignment with organizational goals. Lead project execution, manage risks, and coach teams to exceed client expec...
5 days ago
Clinical Documentation Integrity Supervisor
$110K - $159K *
Inspire excellence in clinical documentation by leading a team of specialists, ensuring quality assurance, and fostering professional development. Collaborate with stakeholders to enhance operational...
Reposted 5 days ago
Regional Sales Manager (RSM) - PNW (Remote)
$280K - $360K *
Accelerate progress at building and expanding a territory across the Pacific Northwest and Mountain Range States, driving enterprise software sales and fostering relationships with key stakeholders in...
5 days ago
$175K - $200K *
Join a team that's dedicated to overseeing compliance and security initiatives, including FedRAMP and SOC audits. Collaborate across departments to enhance data protection and drive organizational suc...
5 days ago
$113K - $254K *
Drive innovation by developing scalable Python services and AI-driven solutions. Collaborate with data science teams to enhance pricing automation and improve operational efficiency in a fully remote...
5 days ago
Senior Account Executive, High Tech End User
$132K - $170K *
Transform client relationships and drive growth by consulting with C-level executives to implement strategic solutions that enhance value and satisfaction across major accounts, ensuring retention and...
5 days ago
Sr Director, Analyst - Data Management and AI Readiness
$172K - $202K *
Lead the charge in delivering innovative insights and strategies for clients, leveraging in-depth market analysis and research expertise to address complex challenges and drive actionable results for...
Reposted 5 days ago
$120K - $145K *
Accelerate commercial growth by defining strategies for product families, collaborating across teams to translate market insights into actionable plans that drive revenue, profitability, and customer...
5 days ago
$180K - $220K *
Lead the sales strategy for a healthcare Payer business unit, driving market penetration, revenue growth, and client satisfaction. Collaborate with leadership to shape go-to-market strategies and buil...
5 days ago
Principal Product Marketing Manager
$187K - $220K *
Transform product marketing by shaping positioning, launching AI features, and driving go-to-market strategies. Collaborate with cross-functional teams to influence product direction and execute impac...
5 days ago
$110K - $145K *
Shape the future of energy efficiency by leading complex client programs and strategic initiatives. Drive portfolio success through operational excellence, financial performance, and strong client rel...
5 days ago
$80K - $120K *
Join a mission-driven team as an Account Executive, where you'll engage with K-12 district leaders, build partnerships, and drive sales to improve outcomes for English learners across a diverse territ...
5 days ago
$145K - $165K *
Drive impactful clinical research strategies by collaborating with cross-functional teams, analyzing data, and disseminating findings through publications and presentations. Elevate your career while...
5 days ago
$130K - $150K *
Drive the pre-execution contract lifecycle for pharmacy and medical benefits, ensuring clear agreements and timely completion. Collaborate with cross-functional teams to enhance contracting processes...
5 days ago
Principal Implementation Consultant
$128K - $160K *
Lead the charge in implementing software solutions, guiding clients through complex configurations and best practices. Manage multiple large-scale projects while mentoring teams and ensuring client sa...
5 days ago
Corporate Account Executive - SMB- East
$170K - $200K *
Accelerate sales growth by managing key partnerships and driving cloud solutions. Collaborate with teams to achieve targets, nurture relationships, and deliver exceptional customer experiences while s...
5 days ago
Manager, Accounting and Financial Advisory Services
$124K - $236K *
Reimagine your career by leading a dynamic team in financial advisory. Drive impactful projects with finance executives, enhance reporting processes, and foster client relationships while developing j...
Reposted 5 days ago
Senior Lead Marketing Data Platform Architect
$145K - $193K *
Transform the marketing data landscape by leading the architecture and evolution of a scalable data platform. Drive innovation in analytics, AI, and operational frameworks to enhance marketing strateg...
5 days ago
Director of Peripheral and Closure Marketing (REMOTE)
$158K - $190K *
Shape the future of medical device marketing by leading strategic initiatives for the Americas peripheral and closure portfolios. Drive growth, oversee major product launches, and collaborate with cro...
5 days ago
Regional IVIG & Infusion Sales Specialist
$110K - $130K *
Unlock potential by driving growth in IVIG and specialty infusion services. Build strong provider relationships, educate on treatment options, and collaborate with healthcare teams to enhance patient...
Reposted 5 days ago
$95K - $115K *
Join a team that advances occupational safety management across projects by implementing and overseeing comprehensive safety policies. Collaborate with cross-functional teams to ensure compliance with...
Reposted 5 days ago
Senior SAP ABAP/ Fiori Developer
$73K - $102K *
Join a team that's shaping innovative SAP solutions. Leverage your expertise in ABAP and Fiori to drive impactful projects, enhance client experiences, and contribute to a dynamic consulting environme...
5 days ago
$110K - $130K *
Transform the future of marketing by designing and deploying AI-driven growth systems. This hands-on role merges engineering and marketing to enhance customer engagement and streamline operations thro...
5 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.