Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
Senior Partner marketing Manager, MSP/MSSPs
$145K - $185K *
Champion partner growth by developing and executing multi-tiered GTM strategies, driving revenue expansion across the MSSP and MSP ecosystem while collaborating with sales to enhance market awareness...
4 days ago
$132K - $155K *
Unlock potential by providing advanced technical support and solutions, ensuring exceptional customer experiences. Collaborate with teams to resolve issues, mentor peers, and drive product improvement...
4 days ago
Sr. Project Control Engineer (remote)
$74K - $130K *
Drive financial excellence by managing program life cycles, collaborating across departments, and ensuring accurate projections and reporting to meet business objectives and mitigate risks...
4 days ago
Behavioral Health Medical Director
$215K - $408K *
Drive medical leadership in quality improvement and utilization management, ensuring effective care delivery and cost containment. Collaborate with clinical teams to enhance patient outcomes and suppo...
4 days ago
Associate Director, Advisor Relations
$145K - $175K *
Champion EPAM's growth by leading Advisor Relations strategy across North America. Build trusted relationships with sourcing advisors to drive commercial opportunities and enhance market perception, a...
4 days ago
Associate Director, Medical Strategic Operations (Field)
$175K - $219K *
Help us elevate Field Medical operations by optimizing processes, enhancing communication, and driving strategic initiatives to ensure effective engagement and alignment across teams in a dynamic heal...
4 days ago
Graduate Engineer - Grid Modernization
$81K - $91K *
Champion innovative grid modernization solutions by leveraging advanced engineering techniques and collaborating with clients to enhance medium voltage distribution systems. Drive project design, plan...
4 days ago
$123K - $160K *
Join a team that's redefining education by driving state-level approvals for innovative credentials. Collaborate with partners to enhance client confidence and influence revenue growth in high school...
4 days ago
Senior Engineering Technician (Columbia, MD)
$80K - $95K *
Support the design and maintenance of Electrical SCADA Systems, ensuring efficient monitoring and control of electrical power across various sites. Collaborate with engineers and stakeholders to enhan...
4 days ago
Senior Director, Chapter Impact
$106K - $146K *
Elevate community impact by coaching and mentoring Chapter Executive Directors, enhancing their leadership skills and strategic influence while overseeing a portfolio of five to six Chapters to ensure...
4 days ago
Sr. Professional Development Specialist
$80K - $90K *
Lead the charge in enhancing professional development for infant and early childhood mental health. Collaborate nationally to deliver high-quality training, support certification, and implement innova...
4 days ago
$80K - $95K *
Shape the future of financial content by crafting engaging, SEO-driven copy that informs and converts. Collaborate with SEO experts and compliance teams to produce clear, compliant content that resona...
4 days ago
$150K - $160K *
Lead the charge in driving strategic sales growth within higher education, transforming complex challenges into solutions. Collaborate cross-functionally to enhance market share and establish lasting...
4 days ago
$149K - $198K *
Champion the investigation and diagnosis of complex AV behaviors, driving solutions autonomously across simulation and on-road environments. Utilize Python and custom tools to enhance diagnostic capab...
4 days ago
$100K - $104K *
Manage daily property operations, lead a dedicated team, and drive leasing success while ensuring resident satisfaction and financial performance in a dynamic environment...
4 days ago
Lead Application Modernization Consultant
$125K - $168K *
Pioneer application modernization efforts by leading agile teams, driving technical outcomes, and enhancing developer experiences. Collaborate with clients to deliver measurable business results while...
4 days ago
Senior Director, Business Development and Partnerships
$160K - $200K *
Drive growth by leading strategic partnerships in healthcare tech. Collaborate with executives to shape joint strategies, negotiate impactful deals, and operationalize go-to-market initiatives that en...
4 days ago
Principal Product Manager, AI Workflows
$150K - $180K *
Elevate AI experiences from concept to value by collaborating with engineering and design teams. Drive strategy, build prototypes, and make data-driven decisions to enhance user engagement and product...
4 days ago
$160K - $200K *
Transform client relationships by driving business growth, securing profitable projects, and leveraging market access expertise. Lead teams to exceed expectations while identifying industry trends and...
4 days ago
Staff Systems Engineer - Architecture & Interfaces
$165K - $220K *
Join a team that's redefining avionics systems engineering by translating customer needs into innovative architectures and requirements. Collaborate across domains to deliver high-quality solutions in...
4 days ago
Senior Business Development Director - RWD Licensing
$150K - $180K *
Drive your career with a strategic sales leadership role focused on enterprise growth in healthcare. Lead complex business development efforts, build executive relationships, and shape solutions that...
4 days ago
$130K - $155K *
Lead the AI/ML product strategy across multiple business units, driving integration and data-centric solutions that enhance customer value and revenue growth through innovative workflows and collabora...
4 days ago
Executive Director, Manufacturing
$175K - $210K *
Lead operational excellence in biopharmaceutical manufacturing, overseeing GMP processes, technology transfers, and clinical supply. Drive strategic initiatives, manage CDMO relationships, and build a...
4 days ago
RevOps Strategic Initiatives Manager
$106K - $146K *
Shape the future of our operations by leading a dynamic team to optimize Quote-to-Cash strategies, enhance analytics, and design streamlined workflows, all while collaborating across functions to driv...
Reposted 4 days ago
$280K - $350K *
Unlock potential by leading a high-performing Enterprise sales team to drive revenue growth, mentor talent, and align strategies across departments, ensuring success in complex B2B SaaS solutions for...
4 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.