Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,063

Sort By: Relevance

$101K - $125K *

Drive the execution of immersive projects by providing technical oversight and support, ensuring seamless integration and coordination with partners globally while maintaining high standards of qualit...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitality & Recreation

$80K - $95K *

Accelerate progress at the forefront of cybersecurity by analyzing threats, developing countermeasures, and collaborating with teams to protect critical information systems from malicious activities a...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$85K - $95K *

Engage in the development and execution of automated testing strategies, ensuring software quality through comprehensive test plans and scripts. Collaborate with teams to maintain CI/CD pipelines and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$115K - $125K *

Elevate your career by leading engineering teams in a dynamic environment, driving modernization and integration efforts while ensuring compliance with federal DevSecOps frameworks and delivering inno...

United StatesRemote

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  •   11 - 15 years exp.  •   Information Technology

$95K - $125K *

Join a dynamic team to enhance security in CI/CD pipelines, integrating advanced scanning tools and hardening infrastructure across cloud platforms. Drive vulnerability management and ensure complianc...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$95K - $105K *

Join a dynamic team to provision and manage cloud environments, automate deployments, and ensure robust cloud security. Leverage your expertise in AWS or Azure and OpenShift to drive cloud migrations...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Redefine pharmaceutical care by providing tailored drug management and clinical services. Collaborate with healthcare teams to enhance patient safety, participate in goal-oriented initiatives, and ens...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $190K *

Join a team that's dedicated to delivering exceptional anesthesia care. Provide critical support during surgical and diagnostic procedures while enhancing patient safety and comfort through your exper...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $147K *

Lead a dynamic team in enhancing member-centered care through effective utilization management. Drive quality improvement, ensure compliance, and foster strategic partnerships to optimize healthcare d...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$98K - $132K *

Deliver strategic sourcing solutions for Marketing Services, focusing on Content Production and Media. Collaborate cross-functionally to optimize supplier performance, drive innovation, and ensure com...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$147K - $200K *

Drive strategic category management initiatives for Full-Service CRO, collaborating across teams to optimize procurement processes, reduce costs, and enhance supplier performance while ensuring compli...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$107K - $180K *

Drive the strategy and operations of a dynamic contingent workforce program, enhancing governance and service delivery. Collaborate cross-functionally to implement scalable processes and support inter...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$74K - $118K *

Empower cross-functional teams by managing account workflows, resolving issues, and enhancing service quality. Utilize data-driven insights to streamline processes and mentor team members, ensuring a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$225K - $280K *

Engage as a key technical resource for channel sales, driving success with global partners. Leverage your expertise in networking solutions to enhance relationships, deliver impactful demos, and suppo...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Drive growth by managing end-to-end sales cycles in the Energy sector, enhancing customer relationships, and executing strategies to exceed targets while collaborating with cross-functional teams for...

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  •   Less than 5 years exp.  •   Enterprise Technology

$68K - $105K *

Help us lead enterprise-wide incident responses and internal investigations into misconduct, ensuring compliance and effective fraud detection while collaborating across departments to uphold organiza...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$75K - $108K *

Unlock potential by managing diverse research projects, coordinating operations, and supporting data analysis. Collaborate with interdisciplinary teams to drive impactful educational initiatives and e...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Transform the delivery landscape by leading cross-functional initiatives, mentoring analysts, and driving strategic solutions across business units and external partners. Engage deeply in project exec...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$240K - $379K *

Champion innovative government programs by leading multidisciplinary teams to deploy cutting-edge NVIDIA solutions. Collaborate with diverse stakeholders to ensure successful execution and drive impac...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$83K - $104K *

Lead the charge in managing complex client programs, driving operational excellence and strategic direction while fostering strong stakeholder relationships and ensuring exceptional service delivery...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$188K - $265K *

Accelerate progress at the forefront of AI infrastructure by leading technical direction, ensuring platform architecture meets company ambitions, and fostering collaboration across engineering teams f...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$113K - $155K *

Champion quality excellence by executing business programs across manufacturing sites, collaborating with cross-functional teams to enhance product standards, manage consumer insights, and drive conti...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Food & Beverages

$214K - $309K *

Unlock potential by leading the design and implementation of advanced identity solutions for AI agents. Collaborate across teams to build scalable frameworks and drive technical excellence in a dynami...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$200K *

Drive technical excellence by translating creative visions into actionable plans. Oversee pre-production, CAD drafting, and on-site execution, ensuring projects are delivered safely, on time, and with...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$180K - $220K *

Lead the charge in transforming identity security marketing strategies, driving growth and market leadership. Oversee a dynamic team to enhance product positioning, execute go-to-market plans, and sha...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.