Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,902

Sort By: Relevance

$96K - $118K *

Advance your career by engaging members and coordinating care to enhance health outcomes. Collaborate with diverse teams to drive performance improvements and achieve top NCQA and CMS STARs ratings in...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$64K - $108K *

Join a team that's dedicated to providing exceptional patient care in hemodialysis. As an entry-level RN, you'll assess, plan, and evaluate treatment while collaborating with healthcare professionals...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $140K *

Lead and execute model risk audits, enhancing quantitative capabilities and ensuring compliance with regulatory standards. Collaborate across teams to assess model effectiveness and communicate findin...

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$132K - $251K *

Unlock potential by leading the technical execution of radar system design, development, and sustainment for multiple contracts, ensuring effective team collaboration and project management in a dynam...

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$132K - $251K *

Join a team that's driving innovation in military airborne communication systems. Leverage your expertise to capture new business opportunities while collaborating with cross-functional teams and enga...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $95K *

Lead the charge in overseeing a national Audit & Compliance team, ensuring regulatory adherence, risk management, and operational excellence while driving process improvements and fostering cross-func...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $100K *

Join a team that's redefining the Fine & Decorative Arts landscape. Drive strategic growth by transforming buyer demand into actionable supply opportunities, enhancing seller partnerships, and optimiz...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $185K *

Transform healthcare delivery by overseeing pharmacy operations, driving sales, ensuring compliance, and providing exceptional patient care while developing team members and fostering cross-functional...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$148K - $214K *

Shape the future of vaccine development by designing advanced ML models to predict protein properties, collaborating with cross-functional teams to enhance vaccine candidates and drive innovation in i...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $199K *

Lead the charge in managing municipal infrastructure projects, ensuring timely delivery and adherence to budgets while fostering collaboration among team members and clients to enhance community servi...

Reposted yesterday

  •   11 - 15 years exp.  •   Technical Services

$90K - $130K *

Shape a proactive safety culture by developing and implementing tailored safety programs, ensuring compliance with regulations, and leading risk assessments to create a safe workplace for all employee...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead project delivery by developing strategies, budgets, and schedules. Serve as the primary client contact, guiding stakeholders through design and construction phases while ensuring timely completio...

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$63K - $180K *

Drive AI transformation by building production systems, leveraging LLM APIs, and collaborating on architecture. Engage in hands-on development, testing, and delivery while enhancing client relationshi...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$120K - $145K *

Drive project success by leading end-to-end construction management, ensuring alignment with client objectives, budgets, and schedules while fostering collaboration among stakeholders throughout all p...

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $145K *

Drive project success by leading end-to-end construction management, ensuring alignment with client objectives, and maintaining schedules and budgets across multiple projects while fostering collabora...

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$72K - $110K *

Lead the charge in managing a diverse portfolio of network organizations, fostering relationships, and implementing strategic capacity-building initiatives to enhance organizational performance and su...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$113K - $117K *

Lead the charge in optimizing facility operations, ensuring quality service delivery, and managing client relationships. Drive cost-saving initiatives and compliance while fostering vendor partnership...

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Transform patient care as a Lead Nurse, guiding a dedicated team in reproductive medicine. Drive efficiency, ensure compliance, and enhance patient satisfaction while fostering a collaborative environ...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$141K - $212K *

Advance progress at the intersection of manufacturing and IT by leading the design and integration of Operational Technology systems for new product introductions, ensuring secure and scalable solutio...

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$79K - $130K *

Manage daily lab operations, oversee research personnel, and enhance lab efficiency through innovative practices while ensuring compliance with safety guidelines and quality standards...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Champion the delivery of civil works and architectural projects, overseeing contractors and ensuring high-quality execution from site prep to completion. Leverage your expertise to manage complex site...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$127K - $159K *

Transform corporate communications by crafting compelling content that enhances reputation, engages employees, and supports strategic initiatives. Collaborate across teams to manage projects and ampli...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $128K *

Analyze and monitor security alerts, investigate threats, and enhance SOC processes. Collaborate with teams to ensure cybersecurity measures are effective, while documenting incidents and providing te...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$75K - $142K *

Lead a team of specialists in managing absence and claim cases, ensuring operational excellence and high-quality service delivery while fostering a supportive and growth-oriented environment for team...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $187K *

Lead the charge in implementing and governing collectively bargained agreements, ensuring compliance and operational efficiency across multiple teams. Collaborate with stakeholders to translate contra...

Yesterday

  •   5 - 7 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.