Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,902

Sort By: Relevance

$129K - $177K *

Drive the future of AI integration by designing and delivering agentic workflows that enhance user experiences. Lead a team while actively contributing to production code, ensuring reliable AI systems...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$104K - $143K *

Shape the future of enterprise data capabilities by leading product strategy and agile teams to enhance personalized decision-making across channels. Collaborate with stakeholders to translate busines...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Shape the future of healthcare by leading the Organic Risk Adjustment program. Drive strategic initiatives, foster collaboration across teams, and implement innovative solutions to enhance performance...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$129K - $177K *

Champion the development of intelligent decision systems using machine learning and reinforcement learning to enhance personalized healthcare recommendations, driving impactful outcomes for millions o...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Shape the future of Medicaid wellness by leading innovative strategies and solutions that enhance health outcomes for underserved populations. Collaborate with diverse teams to develop impactful progr...

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  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Join us to shape the future of member experiences in healthcare by leading innovative design projects, collaborating with cross-functional teams, and enhancing service delivery through user-centered d...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$126K - $173K *

Develop and enhance a data-driven decisioning platform, collaborating with cross-functional teams to optimize personalized member experiences while balancing immediate needs with long-term strategic g...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$138K - $191K *

Shape the future of legal operations by managing complex investigations and litigation. Provide expert legal counsel, mitigate risk, and partner with stakeholders to communicate complex issues effecti...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$138K - $190K *

Transform enterprise Test Data Management by leading product vision, strategy, and delivery. Collaborate with stakeholders to ensure secure, compliant, and innovative test data solutions that enhance...

Today

  •   8 - 10 years exp.  •   Healthcare

$104K - $143K *

Empower healthcare transformation by developing strategic initiatives that enhance operational efficiency and clinician productivity. Collaborate cross-functionally to drive impactful solutions and im...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$126K - $173K *

Shape the future of enterprise decisioning by leading cross-functional product initiatives that enhance customer experiences and drive operational readiness across multiple business channels...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$71K - $97K *

Unlock your potential as a Senior Workforce Management Professional, blending strategic analysis with operational execution to enhance staffing and service delivery in a dynamic environment. Drive imp...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$223K - $313K *

Lead the charge in evaluating complex clinical scenarios and authorizing services based on national guidelines and regulatory compliance. Collaborate with healthcare professionals to ensure quality ca...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in developing and executing business strategies to acquire new clients, expand market reach, and drive sustainable revenue growth through consultative selling and strategic relationshi...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$115K - $182K *

Join a team that's shaping the future of ultrasound imaging by integrating hardware and software to create innovative, safe, and scalable solutions that enhance clinical performance and patient care a...

Today

  •   5 - 7 years exp.  •   Healthcare

$87K - $151K *

Unlock potential by providing expert remote clinical applications support for advanced molecular imaging. Leverage your clinical knowledge and customer service skills to enhance productivity and deliv...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$115K - $182K *

Elevate the future of ultrasound imaging by leading system architecture, aligning technology strategy with clinical and business objectives, and mentoring engineering talent to drive innovation and ex...

Today

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Join us to drive strategic customer relationships and sales growth across chemicals markets. You'll influence stakeholders, develop sales strategies, and expand opportunities, ensuring campaigns meet...

Reposted today

  •   8 - 10 years exp.  •   Energy & Utilities

$100K - $120K *

Reimagine your career by joining a dynamic team focused on optimizing Artificial Lift systems. You'll lead technical installations, enhance well productivity, and ensure adherence to safety standards...

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Reposted today

  •   5 - 7 years exp.  •   Energy & Utilities

$81K - $165K *

Unlock potential by managing the financial integrity of a high-impact loyalty program. Ensure compliance, accuracy, and timely reporting while collaborating with cross-functional teams to drive growth...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$337K - $437K *

Join a team that's dedicated to providing comprehensive hematology and oncology care. Collaborate with a multidisciplinary team, engage in patient-centered practices, and contribute to medical educati...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$225K - $240K *

Transform business growth by leading a high-performing sales team, driving strategic initiatives, and enhancing client relationships to accelerate revenue across digital solutions in North America...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Business Services

$90K - $100K *

Champion influencer marketing strategies that drive brand growth, manage client relationships, and execute impactful campaigns. Collaborate cross-functionally to analyze performance and innovate appro...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Media

$72K - $120K *

Transform healthcare performance by utilizing data analysis and insights, leading a collaborative team to enhance client outcomes through effective recommendations and implementations across various p...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$150K - $160K *

Drive financial excellence by leading analysis and insights for sales, margin, and inventory performance. Collaborate with cross-functional teams to enhance decision-making and optimize business strat...

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.