Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,896

Sort By: Relevance

$71K - $120K *

Unlock your potential as a Cybersecurity Control Analyst, driving compliance and control assessments while collaborating with diverse stakeholders to enhance our GRC program and strengthen cybersecuri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$139K - $208K *

Join a team that's transforming Global Supply Chain and ERP processes. As a Staff Business Process Leader, you'll drive process standardization, support ERP transformations, and engage with stakeholde...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$110K - $130K *

Optimize and support database platforms, focusing on MySQL and SQL Server migrations to AWS. Lead performance tuning, replication, and maintenance while collaborating with developers to enhance databa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K *

Take ownership of complex mortgage loan evaluations, ensuring compliance with guidelines while assessing borrower risk. Collaborate with internal teams and vendors to facilitate loan approvals and mai...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$83K - $140K *

Join a dynamic team to drive insurance product design and implementation. Collaborate cross-functionally to manage projects, ensuring alignment with strategic goals while facilitating effective busine...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Transform operations within the Documentary Unit by enhancing processes, managing projects, and coordinating across teams to drive strategic initiatives and support fundraising efforts for impactful d...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Media

$100K - $112K *

Lead the charge in clinical trial monitoring, ensuring compliance and data integrity while managing site operations and training staff. Collaborate with teams to deliver high-quality patient care and...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $112K *

Join a team that's dedicated to advancing clinical research by ensuring high standards of care and compliance in monitoring clinical trials. Leverage your expertise in oncology and clinical monitoring...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Empower your marketing expertise to drive strategy, revenue, and brand positioning across multiple segments. Lead a dynamic team, collaborate with executives, and shape customer advocacy initiatives t...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$136K - $204K *

Transform enterprise marketing by owning ABM strategy, driving pipeline growth, and executing tailored campaigns. Collaborate cross-functionally to engage key accounts and achieve revenue targets thro...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $100K *

Drive integrated marketing strategies that enhance visibility and enrollment for academic programs. Collaborate with leadership to optimize advertising across channels, ensuring alignment with institu...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$70K - $105K *

Collaborate with cross-functional teams to enhance EHR workflows, improve operations, and optimize patient care through effective configuration and analysis of Professional Billing Claims applications...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$175K - $225K *

Join our dynamic Real Estate Tax practice to manage complex tax engagements, advise clients on acquisitions and dispositions, and mentor a talented team. Leverage your expertise in partnership taxatio...

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$99K - $129K *

Join a team that's transforming nonprofit organizations through expert financial management. As an Accounting Manager/Controller, you'll lead financial planning, reporting, and compliance, ensuring ou...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$280K - $481K *

Join a team that's driving growth in advanced therapeutics through strategic leadership, P&L accountability, and innovative business development. Shape the future of RNA oligonucleotide manufacturing...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$163K - $306K *

Champion the future of laboratory innovation by leading global product strategy, connecting emerging technologies and customer insights to drive impactful business initiatives across diverse markets...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $180K *

Join a pioneering team to lead strategic operations in a dynamic healthcare division, driving innovation and excellence in therapeutic development and evaluation while managing a diverse workforce and...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$124K - $180K *

Develop and execute strategic initiatives for a leading healthcare division, overseeing operations, research, and education. Collaborate with executive leadership to enhance performance and drive inno...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$76K - $144K *

Deliver high-quality diagnostic imaging services, ensuring compliance with protocols and regulations. Collaborate with healthcare teams to meet patient needs, maintain equipment, and participate in pe...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$118K - $172K *

Transform patient care by leading nursing teams in a dynamic cardiac surgery ICU. Drive operational excellence, enhance staff development, and ensure high-quality patient outcomes through effective co...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$124K - $180K *

Advance your career by leading administrative direction and research coordination. Collaborate with physicians and scientists to enhance operational efficiency and strategic initiatives within a dynam...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$118K - $172K *

Join a team that's dedicated to delivering exceptional patient care by directing and coordinating nursing services, ensuring staff development, and fostering a safe, positive environment for both pati...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$86K - $110K *

Elevate patient care as a Registered Nurse, advocating for complex needs through assessment, planning, and implementation of care strategies, while collaborating with healthcare teams to ensure optima...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$63K - $102K *

Lead the charge in managing clinical research projects, overseeing staff, and ensuring compliance with protocols. Collaborate with stakeholders to enhance mental health interventions and streamline st...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$106K - $155K *

Partner with us to deliver innovative radiation therapy solutions! Join a dynamic team of medical dosimetrists, collaborating with top oncology specialists to create personalized treatment plans and e...

Northampton, MARemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.