Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,901

Sort By: Relevance

$70K - $110K *

Elevate your career as a CyberArk SME/DevOps Engineer, implementing secure solutions for federal modernization. Leverage your expertise in privileged access management to drive best practices and enha...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $230K *

Transform your career by driving oncology product success and building impactful relationships with healthcare professionals. Leverage your expertise to enhance patient access and deliver innovative s...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Unlock potential by driving oncology product success through strategic relationships and innovative solutions. Lead market engagement, exceed performance goals, and ensure patient access while embodyi...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Drive impactful oncology product promotion by building strong relationships with key stakeholders, exceeding performance goals, and ensuring patient access to innovative therapies within your territor...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Champion the promotion of oncology products, building strong relationships with healthcare professionals to enhance patient access and drive brand success in a competitive market. Leverage clinical ex...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Unlock potential by driving oncology product success through strategic relationships and innovative solutions. Collaborate with healthcare professionals to enhance patient access and exceed performanc...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion immersive experiences by leading creative teams to craft compelling narratives in healthcare and aerospace exhibitions, ensuring impactful audience engagement and innovative design solutions...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$108K - $148K *

Join a team that's redefining process engineering through innovative data analysis, troubleshooting, and technology implementation. Collaborate with customers and lead projects while mentoring junior...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Deliver innovative Appian solutions by developing, enhancing, and maintaining applications while supporting modernization initiatives in a collaborative Agile environment. Troubleshoot issues and ensu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$82K - $229K *

Lead the charge in managing creative projects from inception to delivery, ensuring alignment with brand standards. Collaborate across teams to optimize workflows and maintain quality control for all a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$124K - $149K *

Reimagine player engagement by designing innovative reward systems that enhance gameplay experiences. Collaborate with a dynamic team to create compelling content that captivates and retains players i...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$81K - $94K *

Champion operational excellence across inpatient oncology services, ensuring seamless coordination and support for clinical teams. Drive process improvements and regulatory readiness while managing st...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$86K - $113K *

Empower our team by implementing third-party risk frameworks and conducting assessments. Collaborate globally to enhance operational efficiency and drive risk management practices across our organizat...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$63K - $153K *

Innovate software solutions to enhance business performance while driving digital transformation. Collaborate with diverse teams to deliver exceptional user experiences, adapt to varied client needs...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$150K - $180K *

Champion the security strategy for a cutting-edge platform, focusing on supply chain security, code scanning, and threat modeling. Collaborate with teams to enhance security practices and drive innova...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$86K - $113K *

Empower third-party risk management by executing assessments and collaborating globally. Drive operational efficiency and enhance governance practices across diverse teams while identifying and mitiga...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $160K *

Lead the charge in shaping innovative Network Observability products, driving strategy from concept to launch. Collaborate with cross-functional teams to deliver solutions that empower operators to op...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$169K - $266K *

Lead the development of impactful medical communications in neuroscience, ensuring scientific data is effectively translated for healthcare professionals. Collaborate across functions to enhance engag...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$300K - $350K *

Transform your career by leading a national body imaging service line, optimizing workflows, and enhancing clinical quality standards while mentoring a dedicated team of radiologists across multiple l...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$137K - $215K *

Champion global compliance and audit readiness in Regulatory Affairs. Lead cross-functional collaboration, manage GCP audits, and drive continuous improvement initiatives to enhance processes and ensu...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$166K - $238K *

Lead a dynamic team of Cloud Engineers and DevOps professionals, fostering a culture of reliability and continuous improvement while overseeing cloud operations and infrastructure management for missi...

1 week ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$100K - $120K *

Transform utility project estimating through advanced analysis, mentoring, and collaborative support. Provide best-in-class service, ensuring accuracy and efficiency in project estimations while guidi...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$115K - $140K *

Unlock potential by leading product development for Salesforce Health Cloud solutions. Collaborate with cross-functional teams to prioritize and deliver impactful software that enhances patient servic...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$93K - $141K *

Innovate data solutions by building and maintaining robust pipelines that enhance healthcare data products. Collaborate with cross-functional teams to ensure quality and reliability in data delivery...

Framingham, MARemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$68K - $93K *

Lead the charge in delivering exceptional nursing care by collaborating with a multidisciplinary team to enhance patient outcomes and ensure quality of life, while actively participating in culture ch...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.