Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,901

Sort By: Relevance

$124K - $211K *

Innovate clinical product strategies by analyzing market data and collaborating across departments. Drive product development and regulatory compliance while enhancing clinical initiatives to ensure c...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$92K - $138K *

Lead the strategic management of accounts receivable functions, optimizing cash flow and ensuring compliance. Collaborate with teams to enhance efficiency, resolve escalations, and drive performance a...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$101K - $152K *

Champion innovative solutions by leveraging Epic expertise to enhance operational efficiency and drive strategic initiatives across healthcare environments, ensuring high-performance standards and cli...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$68K - $103K *

Shape the future of revenue cycle management by driving process improvements and reducing denials. Collaborate with teams to analyze trends, implement best practices, and enhance client satisfaction t...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Drive successful public-sector construction projects by managing scope, schedule, and budget while fostering strong client relationships and ensuring quality delivery from inception to closeout...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$70K - $143K *

Advance precision time and frequency technologies by designing and supporting hardware systems for diverse applications, collaborating across teams to ensure high-quality product development and lifec...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$161K - $212K *

Join a team that's driving supply chain excellence for cutting-edge infrared optics. As a Senior Commodity Manager, you'll manage supplier relationships, negotiate agreements, and ensure capacity alig...

6 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$108K - $178K *

Champion client relationships by acquiring and managing high net worth accounts. Provide tailored wealth management solutions while collaborating across teams to meet diverse financial needs and ensur...

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$173K - $290K *

Champion innovation in product development platforms, driving strategy and execution for AI-first tools that enhance collaboration and efficiency across teams. Lead the evolution of platforms, ensurin...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$195K - $312K *

Advance user modeling by driving complex AI projects end-to-end, collaborating with cross-functional teams to translate cutting-edge research into impactful solutions for home shopping experiences...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$255K - $300K *

Join a team that's redefining enterprise sales by owning the full sales cycle, engaging C-suite executives, and driving impactful solutions in a fast-paced environment. Your consultative approach will...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $225K *

Lead the charge in shaping the future of Technology audit and compliance. This leadership role requires strategic collaboration with stakeholders while enhancing global risk frameworks for robust orga...

Reposted 6 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$177K - $338K *

Help us advance women's health through innovative clinical trial strategies, where you will conduct, support, and report on global studies for cutting-edge compounds, ensuring adherence to regulatory...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $190K *

Champion engineering excellence as you lead Agile teams in delivering Duck Creek solutions. Guide talent development and foster collaboration while ensuring scalable, secure, and compliant insurance a...

Reposted 6 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$177K - $338K *

Shape the future of women's health by leading global clinical trials, collaborating with cross-functional teams, and ensuring safety and regulatory compliance in innovative drug development...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $175K *

Join our dynamic team to underwrite and develop profitable middle market business, fostering vital broker relationships and refining our underwriting strategies to drive success in an evolving environ...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$86K - $103K *

Accelerate progress at a dynamic organization by leading specification programs that engage architects and engineers. Drive marketing initiatives, analyze performance, and collaborate with cross-funct...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$210K - $235K *

Advance territory sales performance by building relationships with healthcare providers, executing brand strategy, and ensuring patient-centric support for varegacestat in desmoid tumors. Collaborate...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$86K - $103K *

Join a team that's driving innovation in specification marketing programs. This role focuses on enhancing engagement with architects and engineers, ensuring alignment with business objectives while fo...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$190K - $267K *

Join a team that's redefining web performance and developer experience. You'll tackle complex platform challenges, optimize Shreddit’s architecture, and enhance tooling for a high-traffic site, empowe...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Media

$120K - $208K *

Advance the success of our life insurance sales team by leading strategic support initiatives, enhancing operational efficiency, and fostering collaboration across departments to achieve sales targets...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$69K - $101K *

Empower our Micro-Fulfillment Operations team by ensuring optimal performance and reliability of automated systems. Engage with customers to troubleshoot and resolve complex technical issues, enhancin...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$82K - $144K *

Transform the future of industrial automation by leading large-scale project deployments across North America. Collaborate with cross-functional teams to ensure successful installation and integration...

6 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Transform compensation practices through expert analysis, strategic planning, and market alignment. Join a dynamic team that enhances operational support and governance of compensation programs, ensur...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$82K - $144K *

Drive the deployment of cutting-edge industrial robotics across North America, overseeing project planning, installation, and launch. Collaborate with cross-functional teams to ensure successful integ...

6 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.