Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,901

Sort By: Relevance

$230K - $245K *

Empower your career by leading cross-functional teams in drug development. Drive execution, foster collaboration, and ensure alignment on strategic objectives while navigating a fast-paced environment...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$78K - $128K *

Manage day-to-day operations of a collaborative research lab, ensuring efficient workflows, resource coordination, and team support while contributing to scientific projects and enhancing operational...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$185K - $312K *

Engineer the future of home shopping by developing a foundational AI model that integrates market dynamics, consumer behavior, and economic factors to enhance user experience and decision-making in re...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Shape the future of secure software development by integrating security practices into engineering workflows, building automation tools, and conducting penetration tests to identify vulnerabilities an...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $275K *

Drive strategic customer partnerships and complex transactions in the data center sector, collaborating with cross-functional teams to deliver innovative solutions that align with customer needs and c...

6 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$95K - $105K *

Transform creative visions into tangible assets by managing the entire production lifecycle. Oversee timelines, quality control, and vendor relationships to ensure projects are delivered on-brand, on...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Media

$250K - $325K *

Champion the development of our Middle Market Contract Surety strategy, leading a dedicated team to foster relationships and drive growth while ensuring alignment with existing frameworks and maintain...

Reposted 6 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$80K - $85K *

Optimize kitchen operations by supporting the Executive Chef, managing staff, and ensuring high culinary standards. Play a vital role in menu execution, training, and maintaining food safety in a dyna...

6 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$72K - $116K *

Engage in financial analysis and reporting, developing forecasts and insights. Collaborate across departments to enhance business outcomes and present findings to management, driving strategic decisio...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$127K - $137K *

Unlock potential by leading train operations and ensuring compliance with safety regulations. Oversee T&E crews, manage performance, and implement safety initiatives to optimize service delivery and o...

6 days ago

  •   Less than 5 years exp.  •   Transportation

$170K - $200K *

Unlock potential by leading product strategy for organic discovery and AI visibility across a vast platform. Drive client success through innovative solutions, collaborating with engineering and desig...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $150K *

Unlock the potential of strategic accounts as you build lasting relationships, drive retention, and identify growth opportunities. Be the primary advocate for our major enterprise clients, ensuring sa...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $220K *

Pioneer your career as a Medical Director, leading a new veterinary practice with full ownership opportunities. Enjoy medical autonomy, state-of-the-art facilities, and the chance to shape your clinic...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $115K *

Shape innovative software solutions by designing, developing, and maintaining robust applications. Collaborate with cross-functional teams to enhance user experience and optimize application performan...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $214K *

Drive innovation in network engineering by leading complex automation initiatives. Shape architecture and standards while collaborating across teams to enhance security, reliability, and scalability o...

6 days ago

  •   11 - 15 years exp.  •   Consumer Technology

$157K - $256K *

Transform clinical data management by leading strategic initiatives across programs, ensuring quality and efficiency while collaborating with diverse teams and stakeholders to drive impactful results...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$112K - $257K *

Shape the future of technology for the US Federal Government by designing, deploying, and maintaining Cross Domain Solutions. Leverage your expertise to enhance infrastructure, ensure security, and me...

6 days ago

  •   11 - 15 years exp.  •   Business Services

$135K - $160K *

Transform OEM partnerships by driving strategic growth and innovative solutions. Leverage market insights and relationship-building skills to negotiate impactful deals and collaborate with senior lead...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$300K - $373K *

Unlock your potential as a psychiatrist, focusing on patient care while enjoying flexible scheduling, collaboration with a dedicated team, and access to ongoing learning opportunities in a supportive...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in designing scalable, cloud-based SaaS solutions for Higher Education. Collaborate with cross-functional teams to translate institutional needs into actionable solutions, ensuring ali...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $180K *

Champion innovative marketing strategies and lead a dynamic team to enhance brand identity, drive business growth, and foster a collaborative culture. Oversee budget management, content development, a...

6 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$109K - $197K *

Lead the design and implementation of MuleSoft integration solutions, focusing on API development and cloud deployments. Collaborate with teams to translate business needs into technical specification...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Business Services

$101K - $203K *

Transform product strategy by leading digital product development and enhancements. Collaborate with cross-functional teams to gather insights, prioritize initiatives, and drive innovation that meets...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $215K *

Lead the charge in developing a cutting-edge compliance program for consumer financial products. You'll oversee a team, drive strategy, and ensure adherence to regulations in a fast-paced, innovative...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$145K - $189K *

Lead and inspire a pharmacy team to deliver exceptional patient care, ensuring compliance and operational excellence while fostering a culture of safety and empowerment. Drive performance through coac...

West Chop, MAIn-Person

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.