Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,903

Sort By: Relevance

$106K - $122K *

Advance global immunization efforts by managing strategic partnerships and implementing evidence-based solutions to enhance vaccine demand and delivery in low and middle-income countries, focusing on...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $175K *

Drive new revenue by owning complex sales cycles, engaging with C-suite and technical leaders, and leveraging strategic relationships to penetrate enterprise accounts in a high-performance AI environm...

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$163K - $297K *

Champion the development and execution of innovative digital product strategies across EMEA, enhancing consumer experiences and driving key performance indicators in a high-growth e-commerce environme...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to enhancing patients' daily living skills through tailored occupational therapy. Collaborate with healthcare professionals to deliver skilled care and support patients in...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Manage US customer retention programs to enhance loyalty and value. Lead advocacy initiatives and migration communications, ensuring seamless customer journeys. Collaborate cross-functionally to optim...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to optimizing business applications and enhancing tenant experiences. Collaborate with stakeholders, manage system integrations, and lead projects to ensure seamless opera...

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $145K *

Champion operational excellence at our facility by leveraging engineering expertise to enhance infrastructure systems, ensuring peak efficiency and safety while driving sustainability initiatives thro...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $170K *

Join a team that's driving strategic sales in TMS, WMS, and SaaS solutions. Lead initiatives to achieve sales targets, develop customer relationships, and promote innovative technology offerings while...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Transportation

$91K - $109K *

Lead the charge in maintaining financial integrity by overseeing accounting operations, ensuring compliance with nonprofit standards, and managing audits. Collaborate with finance leadership to produc...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$148K - $164K *

Optimize cloud security operations by monitoring and securing Azure and AWS environments. Collaborate with teams to integrate security into deployment pipelines and ensure compliance with industry sta...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$176K - $229K *

Join us to lead innovative cloud architecture for digital healthcare solutions, integrating Generative AI throughout the software development lifecycle while collaborating with cross-functional teams...

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $200K *

Transform customer engagement by leveraging your engineering expertise to drive sales success. Collaborate with a dynamic team to understand client needs and deliver innovative solutions in the electr...

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Manage and maintain advanced telecommunications systems, ensuring secure and efficient voice and data communications. Collaborate with teams to provide technical support and training while overseeing...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$162K - $243K *

Lead a dynamic team in managing complex clinical research trials, ensuring strategic execution and client satisfaction. Drive project success through effective communication, budget oversight, and qua...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $140K *

Deliver quality assurance excellence by leading factory-specific initiatives, ensuring compliance with standards, and empowering operators to uphold quality at the source while driving continuous impr...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform customer experiences by leveraging advanced observability and AI technologies. Collaborate with sales and engineering teams to drive technical solutions, optimize value, and enhance enterpri...

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Champion the testing of industrial automation systems by developing and executing comprehensive test plans and procedures. Collaborate on software validation and defect resolution while ensuring compl...

6 days ago

  •   Less than 5 years exp.  •   Staffing

$120K - $135K *

Shape the future of project management in global health by leading teams, ensuring timely delivery, and driving operational excellence across multiple projects while aligning with client and business...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$88K - $105K *

Unlock potential by joining our dynamic team to drive drug product development, focusing on formulation and process studies for clinical biologics. Collaborate effectively while executing experiments...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $145K *

Unlock potential by leading insights development and storytelling, managing data analysis, and fostering client relationships. Drive project success through collaboration and high-quality deliverables...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$180K - $220K *

Empower our cloud infrastructure by reimagining deployment processes, enhancing security, and driving AI-first development. Collaborate across teams to build robust systems that support our venues and...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$95K - $115K *

Transform laboratory operations by overseeing all testing departments, ensuring efficient workflow and adherence to quality standards while supervising staff and driving continuous improvement in clin...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Shape the launch of a rare disease GI/Hepatology team by exceeding sales goals, building customer relationships, and implementing effective territory strategies in a compliant manner. Drive success in...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $130K *

Join us in leading on-site installation activities for complex projects. As a key liaison, you'll ensure safety, quality, and schedule adherence while coordinating with diverse stakeholders to drive s...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$158K - $185K *

Unlock your potential by leading the design and delivery of a transformative Medicaid data platform. Collaborate with stakeholders and guide teams to modernize healthcare systems through innovative cl...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.