Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,903

Sort By: Relevance

$110K - $130K *

Transform biologics drug discovery by leading antibody engineering campaigns, optimizing therapeutic formats, and collaborating across teams to advance innovative solutions from concept to candidate n...

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive revenue growth by managing key customer relationships and delivering accurate forecasts. Collaborate with teams to support product development and ensure compliance with industry standards while...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Pioneer engineering excellence by overseeing construction projects, ensuring compliance with standards, and managing documentation. Collaborate with teams to deliver high-quality infrastructure soluti...

5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Shape the future of advanced RF systems integration and testing. Collaborate with experts to ensure seamless hardware and software functionality, leveraging cutting-edge tools and methodologies in a d...

5 days ago

  •   5 - 7 years exp.  •   Staffing

$160K - $200K *

Innovate operational excellence in Clinical Operations by leading strategic initiatives, workforce planning, and cross-functional alignment to drive organizational effectiveness and support clinical d...

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$93K - $114K *

Engage with clients to unlock their potential through diverse therapeutic approaches. Enjoy flexible scheduling and competitive compensation while making a meaningful impact in the lives of individual...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $140K *

Reimagine financial strategy as you drive analytical rigor and strategic clarity in a high-impact role. Collaborate with cross-functional teams to support growth initiatives and shape the future of a...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$62K - $112K *

Join a team of enthusiastic mental health professionals dedicated to transforming the sector by enhancing access and care quality, ensuring both client and clinician satisfaction in a supportive, grow...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$164K - $262K *

Take ownership of software architecture and development to create scalable, user-centric applications. Lead comprehensive development initiatives while optimizing performance and mentoring engineers i...

RemoteRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$200K - $257K *

Join our dynamic team to provide exceptional mental health care through a hybrid model, combining telehealth and in-office support. Collaborate with dedicated professionals while enjoying flexible sch...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$224K - $431K *

Innovate cutting-edge software for data center power management, spanning architecture, firmware, and AI workloads. Drive product lifecycle from design to deployment, enhancing performance and energy...

RemoteRemote

5 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$86K - $99K *

Champion aggressive sales growth by building strategic relationships and generating leads in the insurance housing sector. Drive market share expansion through effective communication and innovative s...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$97K - $121K *

Join a team that's driving digital engagement through innovative content creation and strategic social media campaigns. This role demands agility and creativity to enhance brand presence across multip...

5 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$70K - $118K *

Unlock potential by managing inventory processes across multiple locations, leading a team of 15-25, and ensuring accurate counts and audits. Drive operational excellence while coordinating with third...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$73K - $109K *

Lead daily transportation operations for our Medical Waste Division, focusing on efficiency, compliance, and customer satisfaction. Manage drivers, dispatch, and route planning while promoting safety...

5 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$70K - $118K *

Elevate inventory management by leading a team to ensure accurate counts and audits across multiple supply chain locations, while optimizing processes and maintaining operational excellence through ef...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Empower your career by driving strategic sales initiatives within large healthcare organizations. Own the full sales cycle, build executive relationships, and position a leading clinical collaboration...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$87K - $157K *

Transform the Naval Enterprise Network through Model-Based Systems Engineering, utilizing SysML and CSM tools to develop and manage system models, requirements, and designs while collaborating with st...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Technical Services

$75K - $104K *

Elevate your career by managing comprehensive employee benefits programs. Ensure compliance, provide exceptional service, and collaborate with vendors while analyzing data to enhance offerings. Join a...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Transportation

$100K - $155K *

Lead the charge in building and operating a cutting-edge makerspace, transforming ideas into hardware. Collaborate with scientists and engineers to design, fabricate, and integrate neurotechnologies i...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K *

Champion patient-centered care by joining our telemedicine team, where you'll manage diverse clinical cases through virtual consultations, ensuring flexibility and work-life balance while delivering h...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$144K - $288K *

Engage in a pivotal leadership role overseeing core network infrastructure operations. Drive stability, performance, and security across WAN and LAN environments while mentoring a skilled team and man...

RemoteRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K *

Transform virtual healthcare by delivering compassionate, patient-centered care. Join a dynamic telemedicine team, managing diverse clinical cases while enjoying a flexible schedule that promotes work...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$66K - $145K *

Reimagine rebate reconciliation by managing complex accounts, mentoring analysts, and leading process improvements. Collaborate with internal and external partners to enhance operational efficiency an...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $155K *

Lead the charge in developing a high-performing Solutions Engineering team, delivering innovative customer projects while fostering growth and collaboration. Engage closely with clients to ensure qual...

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.