Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,903

Sort By: Relevance

$90K - $110K *

Unlock your potential by designing advanced PCB layouts and collaborating on innovative RF designs. This remote role requires expertise in Altium and a strong understanding of PCB standards to drive q...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$142K - $190K *

Lead the charge in advancing drug development projects by ensuring high-quality planning, execution, and cross-functional collaboration. Drive strategic initiatives and manage project timelines while...

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $185K *

Lead the charge in designing Azure platforms for healthcare data products, ensuring resilience, security, and cost management while mentoring engineers and shaping architectural standards in a fully r...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$103K - $131K *

Elevate your career by driving member engagement and profitability through innovative strategies for loyalty programs and digital acquisition across multiple channels, ensuring optimal performance and...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$150K - $175K *

Lead the charge in transforming financial operations while ensuring compliance and accuracy. Collaborate with cross-functional teams to enhance processes, manage audits, and drive strategic initiative...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$138K - $189K *

Join a team that's redefining revenue systems by optimizing Salesforce CPQ architecture. Leverage your expertise to design and implement advanced pricing solutions, ensuring seamless Quote-to-Cash pro...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$183K - $220K *

Elevate technical storytelling by creating impactful demos and workshops that bridge the gap between product capabilities and customer understanding, empowering sales teams and enhancing buyer engagem...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $100K *

Lead the clinical team to deliver exceptional care, fostering relationships with residents, families, and healthcare providers while mentoring staff and enhancing satisfaction in a dynamic healthcare...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by managing HubSpot for impactful digital marketing campaigns. Collaborate with cross-functional teams to optimize lead flow, reporting, and website support, ensuring data integrity a...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$106K - $284K *

Reimagine healthcare technology by leading the development of secure, scalable microservices. Collaborate with cross-functional teams to enhance digital solutions that transform patient experiences an...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in optimizing digital enrollment campaigns across multiple channels. Drive strategy, manage vendor relationships, and analyze performance to enhance recruitment efforts and achieve enr...

5 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$124K - $158K *

Join a dedicated team as you lead pharmacy operations, ensuring safe dispensing and patient care. Support your colleagues while enhancing patient experiences through compassionate service and effectiv...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$119K - $150K *

Shape the future of enterprise application integrations by leading technical design and implementation for Finance, Accounting, and Supply Chain projects, collaborating with cross-functional teams to...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Champion client success by managing complex insurance placements, negotiating optimal coverage, and fostering key relationships in the insurance marketplace. Stay informed on industry trends to delive...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$185K - $344K *

Join a team that's redefining market access through innovative data partnerships. Lead strategic collaborations, ensure data compliance, and drive insights that enhance decision-making and patient ser...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$154K - $242K *

Lead the charge in developing and executing global category strategies for Marketing & Sales Support, partnering with stakeholders to drive value, optimize supplier relationships, and enhance business...

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion the clinical supply chain for late-stage oncology trials, ensuring seamless operations and communication between sites, suppliers, and stakeholders. Drive continuous improvement and complianc...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Analyze financial performance and drive insights to enhance profitability. Collaborate with cross-functional teams to develop budgets, forecasts, and reports, ensuring consistent financial processes a...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$177K - $278K *

Lead the charge in enhancing compliance and ethical practices within Global Medical. Collaborate with senior leaders to mitigate risks, develop policies, and drive a culture of integrity while ensurin...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform production planning by leading a dynamic team to optimize non-sterile compounded production. Drive strategic planning, manage capacity, and ensure alignment with demand forecasts while foste...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$175K - $185K *

Transform facilities operations by leading maintenance strategies, enhancing efficiency, and fostering collaboration across teams. Drive best practices and ensure compliance while mentoring leaders to...

5 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$82K - $220K *

Join a team that's dedicated to integrating and testing advanced systems. Lead I&T activities from concept to certification, collaborating across disciplines to ensure robust, reliable solutions while...

5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$155K - $165K *

Unlock your potential as you support the Air Force's modernization efforts through software engineering, collaborating across teams to enhance system performance and mission effectiveness in a dynamic...

5 days ago

  •   11 - 15 years exp.  •   Technical Services

$95K - $115K *

Transform small commercial sales by driving new business, fostering relationships, and collaborating with underwriting teams to achieve growth and profitability while exceeding organizational goals an...

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$60K - $110K *

Lead the charge in executing store remodels and new projects nationwide. Collaborate with teams to ensure timely delivery, budget adherence, and quality standards while developing associates and manag...

5 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.