Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,893

Sort By: Relevance

$100K - $140K *

Transform your career by managing complex environmental projects across New England. Lead diverse teams, mentor junior staff, and cultivate client relationships while ensuring compliance and deliverin...

Today

  •   8 - 10 years exp.  •   Technical Services

$110K *

Join a team that's dedicated to delivering exceptional laser hair removal treatments while traveling nationwide. You'll ensure client satisfaction and continuity of care, blending medical expertise wi...

Today

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Empower legal firms by leading the development of innovative IT solutions, driving market strategies, and enhancing service offerings. Collaborate with cross-functional teams to establish credibility...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$85K - $90K *

Manage board relations and special projects, ensuring effective communication and support for the Executive Director. Collaborate across teams to execute organizational priorities and enhance governan...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$145K - $166K *

Join our team as a Field Construction Manager, overseeing substation and underground transmission projects. Leverage your expertise in civil and electrical construction to ensure safe, efficient proje...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$130K - $155K *

Shape innovative Salesforce solutions by leading design and delivery across multiple clouds. Engage with clients to gather requirements, document solutions, and guide implementation teams in a fully r...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $166K *

Empower project success by overseeing field construction for substation and underground transmission projects. Collaborate with diverse teams to ensure safety, quality, and compliance while driving ti...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$89K - $169K *

Elevate your career by leading content governance in a dynamic environment. Drive compliance, enhance review processes, and collaborate with cross-functional teams to ensure high-quality content deliv...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Unlock your potential as a Solution Architect, leading CRM design and integration for pharma and biotech. Drive innovation with Veeva CRM and Salesforce, ensuring seamless operations and client engage...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$216K - $243K *

Pioneer advancements in vaccine research and development, driving global immunization efforts. Collaborate across teams to ensure compliance and effective delivery of safe vaccines, enhancing public h...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $93K *

Grow your career with a dynamic Finance team as a Staff Accountant, supporting financial operations for R&D programs and USG contracts. Collaborate across departments to ensure accurate financial reco...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the execution of clinical trials by monitoring site activities, ensuring compliance with regulations, and collaborating with teams to achieve study objectives. Play a key role in training site st...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by leading Infor M3 ERP implementations. Drive project success through strategic planning, client management, and cross-functional collaboration while ensuring timely delivery and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Optimize your career by providing critical analytical support for hardware and software installations across various platforms, ensuring compliance with regulations and enhancing operational efficienc...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Shape the future of configuration management by overseeing hardware inventory, documentation, and product releases. Collaborate with teams to implement effective change management processes throughout...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Lead the charge in optimizing top-of-funnel marketing operations, driving measurable pipeline growth through strategic planning, data governance, and team leadership. Collaborate with cross-functional...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$90K - $175K *

Empower mission success by managing COMSEC lifecycle functions, ensuring the security and integrity of communication systems through expert oversight and compliance with national standards...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$135K - $160K *

Innovate and manage large-scale commercial programs, driving cross-functional alignment and revenue growth. Lead end-to-end program development, ensuring operational excellence and strategic execution...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $95K *

Lead the charge in developing and executing a comprehensive talent development strategy, enhancing employee engagement and organizational effectiveness while providing HR partnership support across va...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$128K - $185K *

Lead product strategy and management for enterprise lab solutions, aligning investments with market needs and customer insights. Drive team development and cross-functional collaboration to deliver sc...

Today

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Transform your career by owning the pipeline and driving strategic outreach. Leverage your grit and analytical skills to excel in a fast-paced environment, conducting deep research and executing high...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$129K - $147K *

Champion innovative digital video strategies, focusing on CTV, while leading cross-functional teams to optimize campaign performance and drive growth in a dynamic advertising environment...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Media

$170K - $325K *

Elevate your career by securing and managing the transition to a hybrid-cloud infrastructure. Own identity management, cloud security, and developer tooling while leading incident response and threat...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Optimize energy solutions by leading technical projects, conducting site surveys, and collaborating with teams to deliver innovative, cost-effective strategies that enhance facility performance and su...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$75K - $100K *

Unlock potential by joining a dynamic team of licensed therapists to provide integrated behavioral health care in a pediatric setting, utilizing evidence-based therapies for diverse patient needs in a...

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.