Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$110K - $130K *

Drive customer success by consulting on delivery pipelines and platform engineering. Collaborate with sales and engineering teams to enhance technical solutions and increase win rates in complex deals...

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$160K *

Drive the design and evolution of a modern enterprise data platform, establishing architecture standards and best practices while collaborating with cross-functional teams to deliver scalable, cloud-b...

Boston, MARemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Staffing

$110K - $131K *

Transform complex data into actionable insights, partnering with leaders to enhance strategic decision-making and drive organizational performance through advanced analytics and reporting frameworks...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Technical Services

$80K - $95K *

Empower your career by providing high-quality virtual therapy services. Collaborate with healthcare professionals to deliver effective behavioral health interventions and support clients in their jour...

Boston, MARemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in delivering high-quality virtual therapy services, conducting assessments, and collaborating with healthcare professionals to enhance client care. Join a supportive team dedicated to...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $115K *

Elevate your career by leading transformative projects that enhance business practices and systems. Collaborate with senior leaders to drive initiatives, manage complex projects, and ensure effective...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$200K - $240K *

Lead the charge in enterprise sales by acquiring new logos and building strategic relationships. Drive growth in a competitive market, leveraging your expertise to navigate complex sales cycles and de...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$124K - $169K *

Drive strategic insights and analytics to enhance payer access and pricing strategies for biopharmaceutical products, ensuring optimal patient access in a complex healthcare landscape. Collaborate acr...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $129K *

Champion innovative manufacturing solutions by leading design feedback, quoting, and DFM initiatives. Collaborate cross-functionally to enhance product manufacturability and mentor engineers, driving...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Advance community welfare by leading a local office, managing programs, and fostering partnerships to enhance client self-sufficiency and service delivery in a dynamic environment...

4 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$92K - $139K *

Empower your career by joining a dynamic team focused on tracking and analyzing emerging cyber threats. Engage in proactive research and collaboration to produce actionable intelligence that protects...

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Lead the charge in driving sales for hazardous products across Oregon and Western Washington. Cultivate strong relationships with distributors and contractors to achieve sales targets and enhance prod...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Drive website optimization and search strategy initiatives, enhancing digital visibility and engagement. Collaborate with cross-functional teams to implement SEO, GEO, and technical strategies that el...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$170K - $185K *

Drive impactful IT program initiatives for Federal and SLED Governments, overseeing planning, execution, and financial management while fostering client relationships and identifying growth opportunit...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Join a team that's dedicated to effective project coordination, ensuring seamless communication and management of project activities. Drive efficiency by overseeing material handling, logistics, and a...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$220K - $275K *

Partner with us to drive AI transformation in customer experience. As a Principal Solutions Engineer, you'll guide clients through the design and implementation of innovative AI solutions, ensuring al...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$89K - $139K *

Drive the transformation of employee experiences by leading a multi-year Digital Employee Experience (DEX) program. Oversee analytics, enhance productivity, and implement AI-driven solutions to optimi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $220K *

Join a team that's shaping the future of AI by leading enterprise sales for innovative AI solutions. Engage with top security and AI leaders to drive impactful evaluations and foster long-term partner...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$108K - $130K *

Empower cross-functional teams to execute strategic publication plans, ensuring high-quality scientific communications. Lead and manage resources effectively while fostering collaboration and addressi...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive strategic planning and execution across teams, leveraging data to inform decisions and enhance operational efficiency. Collaborate with leadership to define objectives, manage reporting processe...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$117K - $147K *

Empower multi-site data center and AI infrastructure programs valued at $25M+, leading diverse teams to ensure successful delivery, budget management, and customer satisfaction while driving executive...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$74K - $90K *

Optimize your marketing expertise by managing global campaigns, driving AI adoption, and collaborating cross-functionally to enhance project efficiency and impact in a fast-paced environment...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$107K - $216K *

Transform complex data into actionable insights as you lead end-to-end BI solutions. Collaborate with stakeholders to drive measurable outcomes and ensure data quality while leveraging advanced analyt...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$170K - $220K *

Explore innovative human-systems integration solutions by leading a team of researchers and engineers to enhance user interaction with technology in complex environments, driving impactful research an...

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $100K *

Join a team that's dedicated to providing flexible outpatient therapy services. Enjoy schedule autonomy with hybrid telehealth options while receiving competitive compensation and comprehensive suppor...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.