Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$180K - $260K *

Transform large microscopy volumes into actionable data by designing, training, and evaluating deep learning models. Collaborate across teams to enhance performance and tackle complex problems in a mu...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Advance quality performance initiatives by collaborating across departments to enhance healthcare outcomes, manage data analytics, and ensure compliance with regulatory standards, driving continuous i...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $119K *

Transform the landscape of clinical documentation by educating and mentoring teams, ensuring compliance, and enhancing documentation accuracy to optimize patient care and coding outcomes...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$122K - $423K *

Champion ethical decision-making by leading internal investigations, guiding teams through complex issues, and enhancing policies to uphold integrity and compliance across the organization...

3 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$106K - $260K *

Transform healthcare solutions by leading the design and deployment of AI-powered, cloud-native architectures. Collaborate across teams to deliver scalable, innovative products that meet business need...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive new business generation in captive management solutions, focusing on multifamily risk and large P&C alternatives. Build relationships with brokers and multifamily owners while managing the full...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$99K - $232K *

Join us to lead Oracle Cloud EPM projects, optimizing client operations through innovative solutions and effective team management. Drive success by mentoring staff, coordinating resources, and ensuri...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$155K - $185K *

Join a dynamic team to oversee security operations, incident response, and automation initiatives. Collaborate with cross-functional teams to enhance security practices and develop tools that streamli...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$130K - $155K *

Join a team that's building and optimizing cloud infrastructure to ensure high availability and security for a rapidly scaling platform in the pharma sector. Drive reliability, automation, and collabo...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$219K - $232K *

Join a team that's advancing early discovery programs through IND approval. Lead program management efforts, refine methodologies, and drive execution while fostering cross-functional collaboration an...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $105K *

Unlock potential by managing litigation dockets with precision and accuracy. Collaborate with legal teams to ensure timely processing of docketed events while adhering to compliance guidelines in a dy...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$82K - $132K *

Unlock potential in revenue cycle management by leading innovative solutions, optimizing processes, and collaborating across departments to enhance operational efficiency and maximize revenue impact...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's shaping the future of academic technology by leading strategic initiatives, enhancing collaboration, and implementing innovative solutions to support educational excellence across a...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$186K - $218K *

Innovate with a collaborative team as you build scalable blockchain infrastructure, design APIs, and streamline complex data processes. Your contributions will enhance system reliability and performan...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$106K - $167K *

Pioneer growth as a Senior Field Sales Executive, driving success in the Eastern US. Manage key accounts, develop strategies, and build relationships to enhance customer satisfaction and achieve sales...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$118K - $147K *

Support clinical pharmacy operations by reviewing formulary exceptions and prior authorizations, ensuring compliance and efficiency in medication management across various programs and teams...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $105K *

Play a key role in executing strategic marketing campaigns and event communications within a professional services environment. Collaborate with stakeholders to manage the full lifecycle of marketing...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$115K - $200K *

Optimize 3D printing performance by solving complex engineering challenges. Collaborate with a diverse team to enhance SLA & SLS technologies, focusing on customer needs and innovative solutions for i...

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$118K - $171K *

Transform customer relationships by driving strategic growth in cloud solutions. Engage with enterprise accounts, manage the full sales cycle, and leverage consultative selling to align technology wit...

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $130K *

Elevate security standards by leading risk assessments and policy development. Collaborate with stakeholders to identify vulnerabilities and enhance security posture in demanding environments, ensurin...

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$90K - $100K *

Unlock potential by teaching and coordinating undergraduate statistics programs. Engage students through innovative curriculum development and academic advising while fostering industry partnerships t...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Unlock potential by designing and deploying Power BI solutions that transform data into actionable insights. Collaborate with stakeholders to create scalable models and enhance reporting capabilities...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$64K - $97K *

Transform lives by providing trauma-informed care coordination for seniors facing abuse. Collaborate with community partners to enhance outreach and support services, ensuring a safe environment for v...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$158K - $237K *

Empower product innovation by leading the Lithography Product Management team. Oversee product strategies, development, and customer engagement to ensure seamless execution and alignment with market n...

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$105K - $115K *

Transform branch operations by leading quality assurance, customer satisfaction, and personnel management. Drive growth through effective team development and strategic goal execution while ensuring c...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.