Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.
Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.
Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.
Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.
Average Salary: $125,903
Software/ Systems Engineer III
$82K - $156K *
Contribute to R&D efforts in developing secure, high-performance software solutions for medical devices, ensuring quality and compliance throughout the product lifecycle in a collaborative, hybrid wor...
Reposted yesterday
Regional Product Manager (Protein Diagnostics)
$103K - $154K *
Lead the commercial success of a diverse product portfolio across North America. Drive growth, customer adoption, and lifecycle management while collaborating with cross-functional teams to align stra...
Yesterday
Senior Director, Counsel - Litigation, Legal Policy and Strategy (USA Remote role)
$199K - $321K *
Explore a dynamic role shaping litigation and policy strategy in the pharmaceutical sector. Collaborate with senior leaders and external stakeholders to navigate complex legal landscapes, ensuring pat...
Yesterday
Regulatory Affairs Consultant, CMC - Biologics
$110K - $130K *
Drive your career with a pivotal role in CMC regulatory affairs, ensuring compliance for biologics and small molecules. Collaborate across teams to prepare high-quality submissions and strategies, imp...
Yesterday
Director, Strategic Technology & ISV Partnerships
$150K - $178K *
Champion the growth of strategic technology partnerships, leading initiatives across hyperscalers and cloud marketplaces. Drive revenue, adoption, and integration strategies while managing a high-perf...
Yesterday
3D Computer Vision Researcher - Remote (US)
$135K - $200K *
Unlock potential by advancing 3D vision research through innovative algorithms and open source applications. Collaborate with experts to tackle challenges in photogrammetry and computer vision, contri...
Yesterday
Data Scientist and/or Systems Analyst
$145K - $220K *
Join a dynamic team to drive AI/ML solutions leveraging biological datasets. Contribute technical leadership, develop innovative software architectures, and collaborate across disciplines to enhance n...
Yesterday
Manager, Software Engineering - AI and Data Platform
$133K - $173K *
Lead teams to innovate and enhance robust Data & AI platforms, ensuring scalability and security. Own platform capabilities, drive strategic decisions, and mentor engineers to unlock impactful outcome...
Reposted yesterday
$100K - $150K *
Champion innovative software solutions to enhance bioanalytics and AI/ML applications, driving impactful projects in health data harmonization, web development, and data streaming. Collaborate with a...
Yesterday
Product Manager Water & Wastewater
$125K - $155K *
Lead the development and lifecycle management of membrane products for water and wastewater markets. Collaborate across teams to drive innovation, capture market opportunities, and enhance customer sa...
Yesterday
$89K - $122K *
Unlock potential by providing technical support for complex litigation matters, transforming large data volumes into organized, usable work products. Collaborate with project managers throughout the m...
Yesterday
$120K - $130K *
Elevate your career by leading the design and implementation of complex software solutions. Collaborate with cross-functional teams to drive technical decisions and mentor engineers, ensuring scalable...
Yesterday
Senior Associate, Manufacturing Engineering
$73K - $136K *
Drive innovation in manufacturing engineering to enhance production processes. Collaborate with cross-functional teams to optimize workflows and implement strategies that ensure quality and efficiency...
Yesterday
Manager, Ecosystem Partnerships
$104K - $174K *
Champion ecosystem growth by collaborating across teams to enhance partner operations, drive strategic initiatives, and optimize performance metrics, ensuring value delivery to customers and stakehold...
Reposted yesterday
$95K - $115K *
Join a team that's driving integration data migration strategies and analysis. Collaborate with project teams to execute and support data governance initiatives, ensuring quality and efficiency across...
Yesterday
Director, Clinical Supply Chain (or Senior)
$210K - $230K *
Accelerate progress at the forefront of clinical supply chain management, leading strategic initiatives to ensure seamless delivery of investigational products for global trials while collaborating ac...
Yesterday
VP, Data Strategy & Governance
$180K - $220K *
Drive the enterprise data strategy and governance, ensuring data quality, compliance, and accessibility. Lead cross-functional teams to foster a data-rich culture, enabling advanced analytics and AI r...
Reposted yesterday
$122K - $163K *
Lead the charge in clinical data management, ensuring high-quality deliverables and effective execution across trials. Collaborate with stakeholders, oversee vendor performance, and drive process impr...
Yesterday
$73K - $102K *
Champion ERP solutions by collaborating with stakeholders to customize and integrate systems, ensuring alignment with business goals. Drive enhancements and maintain compliance while delivering effect...
Yesterday
Senior Open Innovation Program Manager
$134K - $205K *
Take ownership of complex federal award programs, driving contract negotiations and ensuring flawless execution across multi-partner initiatives. Collaborate with cross-functional teams to manage sche...
Yesterday
$81K - $137K *
Unlock financial insights by leading complex accounting operations, ensuring accuracy in reporting, and collaborating with cross-functional teams to enhance processes and drive business decisions in a...
Yesterday
$160K - $190K *
Unlock your potential as you lead end-to-end design for complex AI-driven systems. Collaborate with cross-functional teams to create intuitive, secure user experiences that prioritize trust and precis...
Yesterday
$184K - $356K *
Innovate at the forefront of AI infrastructure validation by designing and implementing robust tooling for cluster readiness and certification, ensuring optimal performance for GPU deployments in prod...
Yesterday
Business Development Associate
$70K - $96K *
Empower your career by joining our dynamic team to drive client engagement, identify opportunities, and develop innovative sales strategies. Collaborate with stakeholders and enhance your skills in a...
Yesterday
Healthcare Program & Project Manager (Remote)
$80K - $95K *
Transform healthcare initiatives by leading projects from inception to completion. Coordinate teams, manage timelines, and ensure clear communication to drive organizational priorities and deliver mea...
Yesterday
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.
Where can I find professional jobs in Massachusetts?
Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.
Are the Massachusetts jobs on Ladders vetted?
Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.
How can I find a Massachusetts job that matches my experience?
Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.