Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,150

Sort By: Relevance

$148K - $201K *

Drive category strategy and supplier relationships to enhance Market Access, Pricing, and Health Economics. Collaborate with cross-functional teams to optimize procurement processes and improve operat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$78K - $126K *

Grow your career with a leading professional services firm, providing expert support in Sage Intacct. Engage with clients, troubleshoot issues, and enhance your technical skills in a collaborative, re...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$116K *

Drive impactful site activation strategies, collaborating with cross-functional teams to ensure timely delivery of clinical projects while enhancing communication and mitigating risks throughout the p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$116K *

Lead site activation efforts by coordinating with cross-functional teams to ensure timely and quality delivery of clinical projects. Drive strategic initiatives and mitigate risks while enhancing comm...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$234K - $322K *

Transform global revenue accounting and order-to-cash processes in a dynamic healthcare environment. Lead a high-performing team, ensuring compliance with U.S. GAAP and driving systems improvements fo...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $140K *

Join a dynamic team to enhance cybersecurity programs, engage with clients, and deliver strategic advisory services. Contribute to thought leadership while developing tailored initiatives to protect o...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $140K *

Empower organizations by leading incident response efforts, utilizing advanced forensic techniques to combat sophisticated cyber threats. Collaborate with a dynamic team to deliver impactful security...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $120K *

Shape the future of cybersecurity by analyzing North Korean threats and providing actionable intelligence. Collaborate with experts to uncover insights that drive strategic decisions and enhance secur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$111K - $161K *

Transform the future of energy efficiency by leading a $200M facility upgrade project. Oversee construction, engage stakeholders, and ensure compliance with safety standards while managing resources a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$92K - $134K *

Join us to lead the charge in managing a $32M facility upgrade project, ensuring effective collaboration with teams and stakeholders while maintaining safety and quality standards throughout the const...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Transform your career by leveraging your underwriting expertise to mentor others, handle complex inquiries, and drive process improvements in personal lines insurance. Join a dynamic team dedicated to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Drive regulatory intelligence initiatives to ensure compliance and support clinical research. Collaborate with experts to assess regulatory changes, track global guidelines, and enhance impact assessm...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead global clinical studies across diverse therapeutic areas, ensuring operational excellence and client satisfaction through effective project management and team leadership...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$202K - $289K *

Champion growth in environmental services by leading business development, managing complex projects, and fostering client relationships in the power industry. Leverage your expertise to navigate regu...

United StatesRemote

1 week ago

  •   15+ years exp.  •   Technical Services

$84K - $129K *

Drive the design and development of high-voltage transmission lines, overseeing project teams and ensuring compliance with engineering standards while collaborating with clients and vendors to deliver...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$118K - $180K *

Join a dynamic team to design high-voltage transmission lines, mentor peers, and ensure compliance with engineering standards. Leverage your expertise to deliver innovative solutions and enhance clien...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$81K - $121K *

Join a dynamic team to support brand strategy and visitor engagement initiatives, driving growth and innovation across multiple locations. Collaborate with cross-functional partners to enhance consume...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$73K - $110K *

Join our HR Technology team to optimize HCM, Payroll, and Time & Attendance systems. Collaborate with HR and IT to enhance processes, troubleshoot issues, and ensure data integrity, making a significa...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$50K - $500K *

Grow your career with a dynamic team as you coordinate aircraft scheduling, ensuring seamless communication and logistics for clients and flight crews while adhering to safety regulations and operatio...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$132K - $193K *

Shape the future of customer service by leading ServiceNow transformations, designing scalable processes, and collaborating with stakeholders to enhance client onboarding and service delivery across m...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$93K - $150K *

Support and optimize cloud-based contact center platforms, ensuring service availability and excellent customer experience. Collaborate with teams to troubleshoot complex issues and enhance operationa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$168K - $240K *

Champion AI strategy and governance by leading advisory consulting services, guiding clients from interest to practical adoption. Collaborate with technical teams to deliver integrated solutions and e...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$138K - $183K *

Lead the development and execution of patient support strategies to enhance access and engagement for oncology therapies, collaborating cross-functionally to optimize promotional initiatives and drive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive revenue performance by leading pricing strategy and analytics across brands and properties. Collaborate with cross-functional teams to modernize forecasting and reporting capabilities, leveragin...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$75K - $88K *

Analyze financial compliance and revenue accuracy across franchise operations, ensuring adherence to standards through audits and validations. Serve as a key subject matter expert, guiding franchisees...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.