Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,183

Sort By: Relevance

$163K - $245K *

Optimize enterprise application delivery and security solutions by partnering with key stakeholders to design and implement modern architectures across multi-cloud environments, driving innovation and...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$71K - $98K *

Join a team that's dedicated to providing exceptional customer support and maintaining the performance of advanced Proton Therapy Systems. This role involves hands-on technical expertise and collabora...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in client engagement by driving business growth through innovative solutions, fostering relationships, and collaborating with stakeholders to create value and consensus for transformat...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$130K - $150K *

Join a team that's dedicated to operational excellence by developing training programs and mentoring technicians in Power Systems. Drive improvements and standardization across regions while enhancing...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$140K - $215K *

Join a team that's at the forefront of cyber investigations, leading a skilled pod to combat AI misuse. Drive complex attribution, mentor investigators, and enhance automated detection models while en...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$82K - $172K *

Innovate your career as you design and maintain mission-critical software for defense financial systems. Lead a growing team, integrate AI capabilities, and ensure compliance in both classified and un...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$139K - $232K *

Unlock potential by providing enterprise architecture leadership for Corporate Functions, focusing on Finance and supporting areas. Shape technology strategies and roadmaps to enhance financial manage...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $110K *

Optimize the quality assurance process by leading data analytics and specification development. Drive actionable insights from complaints and non-conformance data while ensuring compliance across manu...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$125K - $165K *

Join a team that's redefining insurance technology delivery by leading SaaS implementation programs. This hands-on role combines project management with team leadership to ensure successful client out...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$81K - $142K *

Lead the design and development of enterprise data management solutions, collaborating with stakeholders to analyze requirements and enhance data processing capabilities using advanced technologies in...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$240K - $300K *

Drive revenue growth by engaging top-tier law firms, cultivating relationships, and executing strategic sales initiatives. Collaborate with leadership to exceed sales targets and enhance market presen...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$240K - $300K *

Partner with us to drive revenue growth by engaging top-tier law firms, cultivating client relationships, and executing strategic sales initiatives that exceed targets in a dynamic, remote environment...

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $120K *

Champion construction project success by providing technical support, ensuring compliance, and conducting quality assurance inspections. Collaborate with contractors and stakeholders to drive project...

6 days ago

  •   Less than 5 years exp.  •   Technical Services

$144K - $170K *

Shape the future of crypto infrastructure by leading the Flexible Custody roadmap, collaborating with cross-functional teams to deliver innovative custody and DeFi solutions for fintechs and corporate...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$136K - $182K *

Redefine commercial pricing strategies by leveraging advanced actuarial analysis, supporting portfolio-level assessments, and mentoring junior colleagues within a dynamic, remote team of professionals...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$200K - $225K *

Lead the charge in optimizing property tax strategies across North America, ensuring compliance and minimizing liabilities. Collaborate cross-functionally to drive impactful decisions and enhance tax...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's shaping the future of aftermarket solutions by driving growth through strategic customer engagement and innovative lifecycle management. Collaborate cross-functionally to enhance pr...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$117K - $161K *

Drive proactive capacity planning and optimization strategies to ensure efficient resource utilization across diverse IT infrastructures, collaborating with technical teams to meet business needs and...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Healthcare

$71K - $97K *

Transform healthcare delivery by conducting assessments, coordinating discharge plans, and collaborating with providers to ensure optimal patient outcomes and continuity of care in acute settings...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $100K *

Elevate workforce planning by transforming data into impactful insights. Partner with leaders to build strategic forecasting tools and measure performance metrics, contributing to operational efficien...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$117K - $161K *

Unlock potential by leading data-driven initiatives to enhance operational performance and strategic outcomes in the VA Contact Center. Collaborate with cross-functional teams to transform complex dat...

Kentucky, USRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$78K - $107K *

Lead the charge in enhancing interoperability and medical documentation processes. As a Senior Process Improvement Professional, you'll design workflows, define operating models, and collaborate with...

Kentucky, USRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$168K - $231K *

Elevate state advocacy and government engagement efforts across Kentucky and West Virginia. Drive strategic initiatives, build key relationships, and align advocacy with business goals to enhance Huma...

Kentucky, USRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$126K - $173K *

Transform provider onboarding and medical documentation processes to enhance compliance and operational efficiency. Lead teams in executing strategies that ensure timely, accurate documentation while...

Kentucky, USRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $143K *

Contribute to strategic clinical operations initiatives that enhance efficiency and standardize workflows. Collaborate across teams to support enterprise readiness and successful program implementatio...

Kentucky, USRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.