Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,183

Sort By: Relevance

$80K - $95K *

Champion procurement excellence by managing vendor relationships, overseeing material purchases, and ensuring compliance across multiple properties while supporting operational needs and budget adhere...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Media

$80K - $95K *

Join a dynamic team as a Quality Engineer, enhancing product quality and driving continuous improvement. Collaborate with cross-functional teams to solve complex challenges and embed quality in operat...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$85K - $100K *

Deliver advanced field service support for Promega instrumentation, ensuring installation, training, and repairs meet customer service standards. Collaborate with teams to enhance service documentatio...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$317K - $443K *

Engage with cross-functional teams to shape the design vision for search and feeds, leading a talented design group to enhance user discovery and community connections while driving growth and retenti...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$80K - $95K *

Join a team that's dedicated to enhancing automation solutions through troubleshooting, programming, and customer collaboration. Leverage your skills to improve machinery performance and ensure seamle...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$245K - $290K *

Champion strategic relationships in community oncology to enhance market access for innovative therapies. Drive account strategies, negotiate contracts, and collaborate cross-functionally to ensure op...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $208K *

Accelerate compliance excellence by leading risk-based monitoring, auditing, and investigations. Drive strategic initiatives, enhance governance processes, and collaborate with stakeholders to ensure...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$167K - $191K *

Oversee the strategic development and execution of HEOR/RWE initiatives, collaborating with cross-functional teams to drive impactful asset strategies and communicate insights effectively for informed...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape the future of client solutions by leading technical discovery and crafting innovative data-driven strategies. Collaborate with sales teams to drive success and ensure seamless implementation of...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Technical Services

$88K - $105K *

Join a dynamic team to drive technical support for lubricants and fluids, collaborating with R&D, Sales, and customers. Leverage your engineering expertise to enhance product development and resolve a...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Champion the deployment of cutting-edge AI systems in diverse environments. Collaborate with teams to ensure seamless installation and operation of hardware and software, while providing exceptional c...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $225K *

Shape the future of a leading security solutions provider by driving growth, operational excellence, and strategic direction. Lead diverse teams and foster innovation to ensure long-term success and c...

6 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$136K - $208K *

Lead the charge in managing complex projects within a matrixed team. Provide expert direction, ensuring safe, efficient operations while maximizing customer satisfaction through effective communicatio...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$242K - $290K *

Empower strategic partnerships by managing alliances, driving collaboration, and ensuring alignment with organizational goals. Leverage your expertise to foster trust and deliver impactful outcomes in...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Drive project success by managing budgets, schedules, and subcontractors while ensuring quality and profitability across multiple large-scale construction sites. Foster strong relationships with stake...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $160K *

Optimize customer networks while delivering integrated networking and cybersecurity solutions. Collaborate globally, enhance performance, and ensure satisfaction as you tackle complex challenges in an...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$100K - $120K *

Lead the monthly close and day-to-day accounting operations, ensuring accuracy and efficiency as the business scales. Collaborate with cross-functional teams to enhance processes and implement automat...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $106K *

Empower clients by leading innovative paid search strategies across diverse categories. Collaborate with cross-functional teams to drive performance, optimize campaigns, and connect search tactics to...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Lead the implementation of safety programs across multiple wind and solar project sites, ensuring compliance and promoting a safe work environment for all team members and contractors. Collaborate wit...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$68K - $105K *

Join a team that's committed to equipment reliability and safety. Lead maintenance operations, manage a unionized team, and drive process improvements within a fast-paced manufacturing environment...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$75K - $135K *

Unlock your potential in a dynamic role where you’ll receive comprehensive training and support to thrive in life insurance sales, with uncapped earning potential and opportunities for advancement...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $140K *

Unlock potential by driving growth and adoption of innovative surgical glaucoma technology. Collaborate with surgeons and staff to deliver exceptional support and education, while building sustainable...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $220K *

Drive impactful healthcare advertising by leading creative teams, overseeing brand strategies, and ensuring high-quality copy and art execution. Collaborate across departments to foster innovation and...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $147K *

Transform complex claims management by supervising 1st and 3rd party auto and commercial injury claims. Lead a remote team, ensuring compliance and operational excellence while fostering strong relati...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $200K *

Empower your career by leading a high-performing sales team to drive profitable growth in the healthcare sector. Develop and execute strategic sales initiatives, foster client relationships, and ensur...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.