Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$104K - $143K *

Champion the alignment of business requirements with implementation teams, ensuring documentation is clear and actionable. Drive the evolution of NBA standards and practices while managing configurati...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$138K - $191K *

Join a team that's redefining healthcare innovation by translating ideas into impactful solutions. Collaborate with senior executives to drive strategic initiatives and enhance population health throu...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$129K - $177K *

Drive the future of AI integration by designing and delivering agentic workflows that enhance user experiences. Lead a team while actively contributing to production code, ensuring reliable AI systems...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $143K *

Shape the future of enterprise data capabilities by leading product strategy and agile teams to enhance personalized decision-making across channels. Collaborate with stakeholders to translate busines...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$155K - $213K *

Elevate your career by leading the design of enterprise Test Data Management solutions. Drive innovation in data privacy and compliance while collaborating across diverse technology domains to deliver...

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $158K *

Shape the future of healthcare by leading the Organic Risk Adjustment program. Drive strategic initiatives, foster collaboration across teams, and implement innovative solutions to enhance performance...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$129K - $177K *

Champion the development of intelligent decision systems using machine learning and reinforcement learning to enhance personalized healthcare recommendations, driving impactful outcomes for millions o...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Join us to shape the future of member experiences in healthcare by leading innovative design projects, collaborating with cross-functional teams, and enhancing service delivery through user-centered d...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$126K - $173K *

Develop and enhance a data-driven decisioning platform, collaborating with cross-functional teams to optimize personalized member experiences while balancing immediate needs with long-term strategic g...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$138K - $190K *

Join us to define and drive the vision for enterprise Test Data Management products, ensuring secure, compliant, and innovative capabilities while collaborating with stakeholders and engineering teams...

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$104K - $143K *

Empower healthcare transformation by developing strategic initiatives that enhance operational efficiency and clinician productivity. Collaborate cross-functionally to drive impactful solutions and im...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $173K *

Shape the future of enterprise decisioning by leading cross-functional product initiatives that enhance customer experiences and drive operational readiness across multiple business channels...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in developing and executing business strategies to acquire new clients, expand market reach, and drive sustainable revenue growth through consultative selling and strategic relationshi...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Business Services

$87K - $151K *

Unlock potential by providing expert remote clinical applications support for advanced molecular imaging. Leverage your clinical knowledge and customer service skills to enhance productivity and deliv...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Reimagine your career by joining a dynamic team focused on optimizing Artificial Lift systems. You'll lead technical installations, enhance well productivity, and ensure adherence to safety standards...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$81K - $165K *

Unlock potential by managing the financial integrity of a high-impact loyalty program. Ensure compliance, accuracy, and timely reporting while collaborating with cross-functional teams to drive growth...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$90K - $100K *

Champion influencer marketing strategies that drive brand growth, manage client relationships, and execute impactful campaigns. Collaborate cross-functionally to analyze performance and innovate appro...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Media

$120K - $145K *

Drive compliance excellence by leading insurance operations, optimizing processes, and mitigating risks across a commercial loan servicing portfolio while ensuring adherence to regulatory and investor...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $100K *

Unlock potential by joining a dynamic team as a Workday Benefits Consultant, where you'll drive client success through innovative solutions, manage multiple projects, and provide expert guidance in th...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $100K *

Join a team that's dedicated to providing exceptional technical support for enterprise software applications. Collaborate with customers and development teams to troubleshoot issues, enhance software...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$135K - $165K *

Optimize commissioning processes by collaborating with teams to ensure quality and adherence to standards. Drive issue resolution and continuous improvement in mission-critical environments, enhancing...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $165K *

Elevate your career by leading commissioning efforts in mission-critical environments. Collaborate with diverse teams to ensure quality assurance, risk mitigation, and successful project delivery whil...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $165K *

Join us to drive excellence in commissioning processes, ensuring quality and reliability in mission-critical facilities. Collaborate with diverse teams to enhance operational readiness and implement b...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$180K *

Transform technical solutions for Federal proposals by leading innovative strategies, collaborating with stakeholders, and ensuring compliance. Drive success through expert writing and systems enginee...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Technical Services

$105K - $211K *

Elevate your sales career by driving full-cycle sales for innovative solutions. Build strong pipelines, engage with clients, and collaborate cross-functionally to enhance customer experiences and achi...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.