Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$84K - $140K *

Unlock potential by driving procurement strategies for advanced manufacturing. Collaborate with teams to manage supplier relationships, oversee bidding processes, and ensure compliance with purchasing...

4 days ago

  •   5 - 7 years exp.  •   Business Services

$170K - $210K *

Lead the design and implementation of cross-platform solutions in AWS GovCloud, focusing on Informatica architecture, security, and CI/CD practices. Collaborate with multidisciplinary teams to ensure...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Lead operational excellence and strategic initiatives to enhance growth, efficiency, and compliance across all facilities. Foster a culture of continuous improvement while overseeing program developme...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$104K - $166K *

Join a team that's dedicated to enhancing cybersecurity operations. As a Senior SOC Analyst, you'll monitor threats, analyze network traffic, and lead incident response efforts while mentoring junior...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$115K - $145K *

Lead security initiatives by collaborating with cross-functional teams to embed security in the software development lifecycle, ensuring robust protection for high-risk product areas while driving ado...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Empower the enterprise by scaling AI governance initiatives across business units. You will lead transformative efforts to ensure responsible AI adoption, influence executive decision-making, and driv...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Transportation

$95K - $115K *

Transform traffic management by optimizing signal systems for efficient movement of people and goods. Collaborate with cross-functional teams to enhance product deployment and support, ensuring safety...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Transportation

$100K - $120K *

Engineer exceptional customer experiences while leading a pharmacy team. Oversee operations, ensure compliance with regulations, and maintain high standards of service and safety. Drive sales and fost...

4 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $120K *

Lead the charge in enhancing internal controls and risk management through independent audits, collaborating with teams to drive innovative solutions and improve business performance in the financial...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Optimize release orchestration and readiness across interdependent solution areas. Drive sequencing, prioritization, and risk management while ensuring delivery health and readiness criteria are met...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$228K - $380K *

Lead the charge in developing a high-performing sales team to drive growth in the Enterprise segment, ensuring consistent achievement of sales targets and fostering collaboration across departments fo...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Business Services

$46K - $122K *

Empower business success through data analysis and reporting. You'll write SQL queries, conduct root cause analyses, and enhance systems to support strategic goals, impacting multiple projects across...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$171K - $214K *

Join us to lead the design and oversight of complex models driving customer lifetime value. Collaborate with engineers and business teams to enhance decision-making across marketing, finance, and prod...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$67K - $111K *

Elevate your career by providing critical analysis and programming support for application software, ensuring a comprehensive and integrated information network that meets diverse customer needs and e...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$103K - $192K *

Shape the future of healthcare reimbursement by leading analytics for payor contracting and out-of-network strategies. Collaborate with cross-functional teams to optimize financial outcomes and drive...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing employee engagement and performance through strategic HR initiatives. Collaborate with leaders to drive talent development and foster a positive workplace cul...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$158K - $199K *

Join a dynamic team to lead, coach, and develop sales associates, driving revenue growth through strategic execution and talent retention. Foster C-level relationships and enhance team success in a co...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Business Services

$85K - $90K *

Join a team that's driving revenue growth and building client relationships in the Southeast. As a key brand ambassador, you'll promote exclusive products and deliver exceptional customer experiences...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$90K - $110K *

Drive your career forward by mastering sales and mentoring others. In this dynamic role, you'll learn our systems, sell our products, and lead a team of sales agents to achieve high performance and gr...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Accelerate progress at a dynamic organization by leading all aspects of accounting operations, ensuring compliance, and driving efficiency. Mentor global teams while collaborating on strategic initiat...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$96K - $181K *

Lead cross-functional teams to optimize application capabilities and enhance business processes. Provide strategic business analysis and project support to ensure quality and alignment with organizati...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Drive impactful projects by collaborating across teams to enhance operational efficiency and deliver innovative solutions. Leverage your expertise to influence strategic decisions and contribute to a...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $99K *

Engage with cross-functional teams to deliver enterprise APIs, ensuring seamless integration and support for mission-critical applications. Collaborate with partners to translate business needs into t...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $150K *

Empower construction teams by optimizing financial workflows and technology solutions. Serve as a subject matter expert in cost management, collaborating with stakeholders to enhance project cost cont...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$170K - $213K *

Transform customer engagement by leading omnichannel marketing strategies, collaborating with cross-functional teams, and leveraging data insights to enhance HCP and patient experiences in the pharmac...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.