Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,150

Sort By: Relevance

$150K - $500K *

Shape the future of mortgage lending by leveraging innovative technology and dedicated support to drive growth and streamline operations for maximum productivity and success in closing deals...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$116K - $146K *

Manage quality assurance for PV EPC projects, ensuring compliance with standards and regulations. Oversee inspections, audits, and training while collaborating with teams to enhance project quality an...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Lead the charge in shaping market strategies and messaging for innovative traffic management solutions, collaborating across teams to drive customer engagement and adoption through compelling content...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Transportation

$100K - $120K *

Elevate traffic management solutions by driving revenue through strategic partnerships with government agencies. Cultivate relationships, identify opportunities, and execute sales strategies to achiev...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Transportation

$100K - $120K *

Unlock potential by creating exceptional customer experiences while leading a pharmacy team. Ensure compliance with regulations, manage inventory, and achieve sales goals, all while fostering a safe a...

3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$135K - $165K *

Elevate user experiences by leading content design strategies across diverse product areas. Collaborate with cross-functional teams to create meaningful conversational AI interfaces, focusing on healt...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing project efficiency and effectiveness. Support PMO processes and tools while collaborating across departments to ensure successful project delivery aligned wit...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$97K - $144K *

Champion transformative corporate partnerships that drive funding and engagement, managing a portfolio generating $5-$10 million annually. Collaborate with Fortune 500 companies to align business obje...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $105K *

Drive innovative video content creation by leading a talented team, ensuring high standards in storytelling and technical quality while embracing new trends and technologies to engage audiences effect...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Media

$82K - $123K *

Shape the future of integrated resource planning by managing transmission domain projects. Collaborate with cross-functional teams to ensure accurate planning assumptions and deliver impactful insight...

3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$75K - $100K *

Join a team that's dedicated to enhancing information security and compliance operations. This mid-level role focuses on supporting security workflows, documentation, and IT service desk escalations...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$185K - $344K *

Champion the evolution of field intelligence capabilities, driving strategic governance and analytics integration to enhance decision-making and execution support across the organization, ensuring ali...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Elevate your career by managing client relationships and retirement plan administration. Drive client satisfaction and retention through proactive service, issue resolution, and expert consultation in...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Transform your career by mastering sales techniques and leading a dynamic team. This role focuses on personal sales excellence and training others to achieve high performance, ensuring growth and succ...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$57K - $178K *

Champion the administration of estates and trusts, ensuring compliance and accuracy in tax filings while managing client relationships and case documentation. Leverage your expertise to deliver except...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$90K - $110K *

Pioneer a unified marketing infrastructure by managing automation platforms, lead intelligence, and analytics. Collaborate with cross-functional teams to enhance data governance and optimize marketing...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Advance global drug safety initiatives by leading pharmacovigilance activities, ensuring compliance with regulations, and collaborating with cross-functional teams to enhance product safety and operat...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $157K *

Optimize compliance processes by leveraging your expertise in Medicare regulations. Collaborate with leadership to ensure adherence to CMS requirements, conduct risk assessments, and support audit rea...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$143K - $194K *

Join a team that drives the execution of integrated media plans, ensuring compliance and operational excellence. Collaborate with cross-functional teams while enhancing brand strategies in healthcare...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$68K - $105K *

Transform your career by configuring and supporting Epic applications. Engage in systems analysis, design, and problem resolution while collaborating with end-users to enhance their experience and str...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a team that shapes global regulatory strategy in a fast-paced environment. You will lead comprehensive regulatory plans, ensuring alignment and execution from development to post-marketing, impac...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's focused on driving partner growth in the travel industry. Leverage your expertise to build relationships, implement strategic plans, and engage clients, all while thriving in a coll...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$88K - $105K *

Drive operational excellence by owning the Professional Services intake and workflow governance processes, ensuring efficient request management and seamless team collaboration to enhance service deli...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Shape the future of talent acquisition by managing end-to-end recruitment processes, collaborating with cross-functional teams, and optimizing hiring strategies to attract top talent in a fast-paced e...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Transportation

$80K - $95K *

Analyze product support for HSA and FSRA offerings, managing deployment, education, and communication. Collaborate with diverse teams to enhance customer experience and drive product effectiveness in...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.